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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Vesicular shuttle model
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Animation for the vesicular shuttle model of Golgi transport. Judith Stoffer View Media
Prion protein fibrils 1
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Recombinant proteins such as the prion protein shown here are often used to model how proteins misfold and sometimes polymerize in neurodegenerative disorders. This prion protein was expressed in E. Ken Pekoc (public affairs officer) and Julie Marquardt, NIAID/ Rocky Mountain Laboratories View Media
Dose response curves
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Dose-response curves determine how much of a drug (X-axis) causes a particular effect, or a side effect, in the body (Y-axis). Featured in Medicines By Design. Crabtree + Company View Media
Hydra 06
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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View Media
Pathways: What's the Connection? | Different Jobs in a Science Lab
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Learn about some of the different jobs in a scientific laboratory and how researchers work as a team to make discoveries. National Institute of General Medical Sciences View Media
Myelinated axons 2
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Top view of myelinated axons in a rat spinal root. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
mDia1 antibody staining-01
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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View Media
Pig trypsin (1)
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A crystal of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Cells use bubble-like structures called vesicles to transport cargo
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Cells use bubble-like structures called vesicles (yellow) to import, transport, and export cargo and in cellular communication. A single cell may be filled with thousands of moving vesicles.Tatyana Svitkina, University of Pennsylvania View Media
Induced stem cells from adult skin 03
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The human skin cells pictured contain genetic modifications that make them pluripotent, essentially equivalent to embryonic stem cells. James Thomson, University of Wisconsin-Madison View Media
Misfolded proteins in mitochondria, 3-D video
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Three-dimensional image of misfolded proteins (green) within mitochondria (red). Related to image 5878. Rong Li, Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University View Media
Synapses in culture
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Cultured hippocampal neurons grown on a substrate of glial cells (astrocytes). The glial cells form the pink/brown underlayment in this image. The tan threads are the neurons. National Center for Microscopy and Imaging Research View Media
Fruit fly ovary_2
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A fruit fly ovary, shown here, contains as many as 20 eggs. Fruit flies are not merely tiny insects that buzz around overripe fruit--they are a venerable scientific tool. Denise Montell, University of California, Santa Barbara View Media
Introns
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Genes are often interrupted by stretches of DNA (introns, blue) that do not contain instructions for making a protein. Crabtree + Company View Media
Stem cell differentiation
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Undifferentiated embryonic stem cells cease to exist a few days after conception. In this image, ES cells are shown to differentiate into sperm, muscle fiber, hair cells, nerve cells, and cone cells. Judith Stoffer View Media
Breast cancer cells change migration phenotypes
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Cancer cells can change their migration phenotype, which includes their shape and the way that they move to invade different tissues. Bo Sun, Oregon State University. View Media
Closeup of fluorescent C. elegans showing muscle and ribosomal protein
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Closeup of C. elegans, tiny roundworms, with a ribosomal protein glowing red and muscle fibers glowing green. Researchers used these worms to study a molecular pathway that affects aging. Jarod Rollins, Mount Desert Island Biological Laboratory. View Media
Lipid raft
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Researchers have learned much of what they know about membranes by constructing artificial membranes in the laboratory. Judith Stoffer View Media
H1N1 Influenza Virus
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CellPack image of the H1N1 influenza virus, with hemagglutinin and neuraminidase glycoproteins in green and red, respectively, on the outer envelope (white); matrix protein in gray, and ribonucleoprot Dr. Rommie Amaro, University of California, San Diego View Media
CRISPR Illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
RSV-Infected Cell
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Viral RNA (red) in an RSV-infected cell. Eric Alonas and Philip Santangelo, Georgia Institute of Technology and Emory University View Media
Fruit fly egg ooplasmic streaming
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Two fruit fly (Drosophila melanogaster) egg cells, one on each side of the central black line. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media
Glycan arrays
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The signal is obtained by allowing proteins in human serum to interact with glycan (polysaccharide) arrays. The arrays are shown in replicate so the pattern is clear. Ola Blixt, Scripps Research Institute View Media
Floral pattern in a mixture of two bacterial species, Acinetobacter baylyi and Escherichia coli, grown on a semi-solid agar for 48 hours (photo 2)
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Floral pattern emerging as two bacterial species, motile Acinetobacter baylyi (red) and non-motile Escherichia coli (green), are grown together for 48 hours on 1% agar surface from a sma L. Xiong et al, eLife 2020;9: e48885 View Media
RAC1 activation in motile fibroblast
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Novel biosensor system maps the timing and location of Rac protein activation in a living mouse embryo fibroblast. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View Media
Animal cell membrane
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The membrane that surrounds a cell is made up of proteins and lipids. Judith Stoffer View Media
Fruit fly spermatids
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Developing spermatids (precursors of mature sperm cells) begin as small, round cells and mature into long-tailed, tadpole-shaped ones. Lacramioara Fabian, The Hospital for Sick Children, Toronto, Canada View Media
3-D Architecture of a Synapse
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This image shows the structure of a synapse, or junction between two nerve cells in three dimensions. From the brain of a mouse. Anton Maximov, The Scripps Research Institute, La Jolla, CA View Media
Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 02
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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media
CRISPR Illustration Frame 2
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
Soft X-ray tomography of a pancreatic beta cell
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A color-coded, 3D model of a rat pancreatic β cell. This type of cell produces insulin, a hormone that helps regulate blood sugar. Carolyn Larabell, University of California, San Francisco. View Media
Zebrafish head vasculature
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A zebrafish head with blood vessels shown in purple. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media
Map of protein structures 01
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A global "map of the protein structure universe." The Berkeley Structural Genomics Center has developed a method to visualize the vast universe of protein structures in which proteins of similar struc Berkeley Structural Genomics Center, PSI View Media
Planting roots
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At the root tips of the mustard plant Arabidopsis thaliana (red), two proteins work together to control the uptake of water and nutrients. Philip Benfey, Duke University View Media
Hippocampal neuron from rodent brain
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Hippocampal neuron from rodent brain with dendrites shown in blue. The hundreds of tiny magenta, green and white dots are the dendritic spines of excitatory synapses. Shelley Halpain, UC San Diego View Media
Mapping disease spread
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How far and fast an infectious disease spreads across a community depends on many factors, including transportation. These U.S. David Chrest, RTI International View Media
Serum albumin structure 1
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Serum albumin (SA) is the most abundant protein in the blood plasma of mammals. SA has a characteristic heart-shape structure and is a highly versatile protein. Wladek Minor, University of Virginia View Media
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 3
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media
In vitro assembly of a cell-signaling pathway
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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View Media
Mouse Brain Cross Section
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The brain sections are treated with fluorescent antibodies specific to a particular protein and visualized using serial electron microscopy (SEM). Anton Maximov, The Scripps Research Institute, La Jolla, CA View Media
Pollen grains: male germ cells in plants and a cause of seasonal allergies
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Those of us who get sneezy and itchy-eyed every spring or fall may have pollen grains, like those shown here, to blame. Edna, Gil, and Amit Cukierman, Fox Chase Cancer Center, Philadelphia, Pa. View Media
HIV Infected Cell
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The human immunodeficiency virus (HIV), shown here as tiny purple spheres, causes the disease known as AIDS (for acquired immunodeficiency syndrome). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Cells frozen in time
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The fledgling field of X-ray microscopy lets researchers look inside whole cells rapidly frozen to capture their actions at that very moment. Here, a yeast cell buds before dividing into two. Carolyn Larabell, University of California, San Francisco, and the Lawrence Berkeley National Laboratory View Media
Arabidopsis leaf injected with a pathogen
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This is a magnified view of an Arabidopsis thaliana leaf eight days after being infected with the pathogen Hyaloperonospora arabidopsidis, which is closely related to crop pathogens that Jeff Dangl, University of North Carolina, Chapel Hill View Media
Lily mitosis 12
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media
RNA folding in action
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An RNA molecule dynamically refolds itself as it is being synthesized. When the RNA is short, it ties itself into a “knot” (dark purple). Julius Lucks, Northwestern University View Media
Sea urchin embryo 05
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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View Media
Fruit fly sperm cells
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Developing fruit fly spermatids require caspase activity (green) for the elimination of unwanted organelles and cytoplasm via apoptosis. Hermann Steller, Rockefeller University View Media
Two mouse fibroblast cells
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Two mouse fibroblasts, one of the most common types of cells in mammalian connective tissue. They play a key role in wound healing and tissue repair. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media
