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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 5

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Vimentin in a quail embryo

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Confocal image showing high levels of the protein vimentin (white) at the edge zone of a quail embryo. Cell nuclei are labeled green. Andrés Garcia, Georgia Tech View Media

Cell toxins

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A number of environmental factors cause DNA mutations that can lead to cancer: toxins in cigarette smoke, sunlight and other radiation, and some viruses. Judith Stoffer View Media

VDAC-1 (3)

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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media

Self-organizing proteins

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Under the microscope, an E. coli cell lights up like a fireball. Each bright dot marks a surface protein that tells the bacteria to move toward or away from nearby food and toxins. View Media

Cultured cells

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This image of laboratory-grown cells was taken with the help of a scanning electron microscope, which yields detailed images of cell surfaces. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

DDR2 Receptors Attach to Collagen in Breast Tumor

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On the left, the boundary of a breast tumor (yellow) attaches to collagen fibers that are closest to it (green) using DDR2. On the right, a tumor without DDR2 remains disconnected from the collagen. Callie Corsa and Suzanne Ponik, Washington University School of Medicine in St. Louis View Media

Vesicular shuttle model

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Animation for the vesicular shuttle model of Golgi transport. Judith Stoffer View Media

The 26S proteasome engages with a protein substrate

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The proteasome is a critical multiprotein complex in the cell that breaks down and recycles proteins that have become damaged or are no longer needed. Andreas Martin, HHMI View Media

Intracellular forces

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Force vectors computed from actin cytoskeleton flow. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View Media

Protein from Methanobacterium thermoautotrophicam

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A knotted protein from an archaebacterium called Methanobacterium thermoautotrophicam. This organism breaks down waste products and produces methane gas. Midwest Center For Structural Genomics, PSI View Media

Neuron with labeled synapses

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In this image, recombinant probes known as FingRs (Fibronectin Intrabodies Generated by mRNA display) were expressed in a cortical neuron, where they attached fluorescent proteins to either PSD95 (gre Don Arnold and Richard Roberts, University of Southern California. View Media

HIV-1 virus in the colon

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A tomographic reconstruction of the colon shows the location of large pools of HIV-1 virus particles (in blue) located in the spaces between adjacent cells. Mark Ladinsky, California Institute of Technology View Media

Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 03

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Nerve cell

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Nerve cells have long, invisibly thin fibers that carry electrical impulses throughout the body. Some of these fibers extend about 3 feet from the spinal cord to the toes. Judith Stoffer View Media

Bacterial glucose isomerase

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A crystal of bacterial glucose isomerase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

EM of yeast cell division

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Cell division is an incredibly coordinated process. Matthew West and Greg Odorizzi, University of Colorado View Media

Lily mitosis 01

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A light microscope image shows the chromosomes, stained dark blue, in a dividing cell of an African globe lily (Scadoxus katherinae). Andrew S. Bajer, University of Oregon, Eugene View Media

Cell division with late aligning chromosomes

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This video shows an instance of abnormal mitosis where chromosomes are late to align. Gary Gorbsky, Oklahoma Medical Research Foundation View Media

Fruit fly ovary

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In this image of a stained fruit fly ovary, the ovary is packed with immature eggs (with DNA stained blue). The cytoskeleton (in pink) is a collection of fibers that gives a cell shape and support. Crystal D. Rogers, Ph.D., University of California, Davis, School of Veterinary Medicine; and Mariano A. Loza-Coll, Ph.D., California State University, Northridge. View Media

Wound healing in process

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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View Media

Magnetic Janus particle activating a T cell

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A Janus particle being used to activate a T cell, a type of immune cell. Yan Yu, Indiana University, Bloomington. View Media

Egg comparison

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The largest human cell (by volume) is the egg. Human eggs are 150 micrometers in diameter and you can just barely see one with a naked eye. In comparison, consider the eggs of chickens...or ostriches! Judith Stoffer View Media

VDAC-1 (4)

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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media

Xenopus laevis egg

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Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View Media

Transmission electron microscopy showing cross-section of the node of Ranvier

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Nodes of Ranvier are short gaps in the myelin sheath surrounding myelinated nerve cells (axons). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Mitosis - telophase

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Telophase during mitosis: Nuclear membranes form around each of the two sets of chromosomes, the chromosomes begin to spread out, and the spindle begins to break down. Judith Stoffer View Media

Cas4 nuclease protein structure

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This wreath represents the molecular structure of a protein, Cas4, which is part of a system, known as CRISPR, that bacteria use to protect themselves against viral invaders. Fred Dyda, NIDDK View Media

Pigment cells in fish skin

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Pigment cells are cells that give skin its color. David Parichy, University of Washington View Media

Regeneration of Mouse Ears

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Normal mice, like the B6 breed pictured on the left, develop scars when their ears are pierced. Ellen Heber-Katz, The Wistar Institute View Media

Sheep hemoglobin crystal

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A crystal of sheep hemoglobin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

800 MHz NMR magnet

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Scientists use nuclear magnetic spectroscopy (NMR) to determine the detailed, 3D structures of molecules. Asokan Anbanandam, University of Kansas View Media

HIV Infected Cell

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The human immunodeficiency virus (HIV), shown here as tiny purple spheres, causes the disease known as AIDS (for acquired immunodeficiency syndrome). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Bence Jones protein MLE

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A crystal of Bence Jones protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Neural development

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Using techniques that took 4 years to design, a team of developmental biologists showed that certain proteins can direct the subdivision of fruit fly and chicken nervous system tissue into the regions Mieko Mizutani and Ethan Bier, University of California, San Diego, and Henk Roelink, University of Washington View Media

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