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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Student overseeing protein cloning robot

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Student Christina Hueneke of the Midwest Center for Structural Genomics is overseeing a protein cloning robot. Midwest Center for Structural Genomics View Media

HIV-1 virus in the colon

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A tomographic reconstruction of the colon shows the location of large pools of HIV-1 virus particles (in blue) located in the spaces between adjacent cells. Mark Ladinsky, California Institute of Technology View Media

Xenopus laevis embryos

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Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. The frog embryo on the left lacks the developmental factor Sizzled. Michael Klymkowsky, University of Colorado, Boulder View Media

Math from the heart

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Watch a cell ripple toward a beam of light that turns on a movement-related protein. View Media

Antitoxin GhoS (Illustration 2)

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Structure of the bacterial antitoxin protein GhoS. GhoS inhibits the production of a bacterial toxin, GhoT, which can contribute to antibiotic resistance. Rebecca Page and Wolfgang Peti, Brown University and Thomas K. Wood, Pennsylvania State University View Media

NCMIR mouse tail

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Stained cross section of a mouse tail. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

HeLa cells

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Multiphoton fluorescence image of cultured HeLa cells with a fluorescent protein targeted to the Golgi apparatus (orange), microtubules (green) and counterstained for DNA (cyan). National Center for Microscopy and Imaging Research (NCMIR) View Media

Cell division phases in Xenopus frog cells

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These images show three stages of cell division in Xenopus XL177 cells, which are derived from tadpole epithelial cells. They are (from top): metaphase, anaphase and telophase. Claire Walczak, who took them while working as a postdoc in the laboratory of Timothy Mitchison View Media

G switch (with labels and stages)

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The G switch allows our bodies to respond rapidly to hormones. G proteins act like relay batons to pass messages from circulating hormones into cells. Crabtree + Company View Media

Dense tubular matrices in the peripheral endoplasmic reticulum (ER) 2

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Three-dimensional reconstruction of a tubular matrix in a thin section of the peripheral endoplasmic reticulum between the plasma membranes of the cell. Jennifer Lippincott-Schwartz, Howard Hughes Medical Institute Janelia Research Campus, Virginia View Media

Body toxins

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Body organs such as the liver and kidneys process chemicals and toxins. These "target" organs are susceptible to damage caused by these substances. Crabtree + Company View Media

Microsporidia in roundworm 2

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Many disease-causing microbes manipulate their host’s metabolism and cells for their own ends. Keir Balla and Emily Troemel, University of California San Diego View Media

Bacterial ribosome assembly

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3D reconstructions of two stages in the assembly of the bacterial ribosome created from time-resolved cryo-electron microscopy images. Ribosomes translate genetic instructions into proteins. Joachim Frank, Columbia University. View Media

NCMIR Tongue 2

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Microscopy image of a tongue. One in a series of two, see image 5810 National Center for Microscopy and Imaging Research (NCMIR) View Media

Confocal microscopy of perineuronal nets in the brain 1

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The photo shows a confocal microscopy image of perineuronal nets (PNNs), which are specialized extracellular matrix (ECM) structures in the brain. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Neuron with labeled synapses

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In this image, recombinant probes known as FingRs (Fibronectin Intrabodies Generated by mRNA display) were expressed in a cortical neuron, where they attached fluorescent proteins to either PSD95 (gre Don Arnold and Richard Roberts, University of Southern California. View Media

ARTS triggers apoptosis

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Cell showing overproduction of the ARTS protein (red). ARTS triggers apoptosis, as shown by the activation of caspase-3 (green) a key tool in the cell's destruction. The nucleus is shown in blue. Hermann Steller, Rockefeller University View Media

Insulin production and fat sensing in fruit flies

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Fourteen neurons (magenta) in the adult Drosophila brain produce insulin, and fat tissue sends packets of lipids to the brain via the lipoprotein carriers (green). Akhila Rajan, Fred Hutchinson Cancer Center View Media

Pig trypsin (1)

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A crystal of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Lysosome clusters around amyloid plaques

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It's probably most people's least favorite activity, but we still need to do it--take out our trash. Otherwise our homes will get cluttered and smelly, and eventually, we'll get sick. Swetha Gowrishankar and Shawn Ferguson, Yale School of Medicine View Media

Neutrophil-like cells migrating in a microfluidic chip

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Neutrophil-like cells (blue) in a microfluidic chip preferentially migrating toward LTB4 over fMLP. Caroline Jones, University of Texas at Dallas. View Media

Automated crystal screening system

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Automated crystal screening systems such as the one shown here are becoming a common feature at synchrotron and other facilities where high-throughput crystal structure determination is being carried Southeast Collaboratory for Structural Genomics View Media

Suicidal Stem Cells

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Embryonic stem cells store pre-activated Bax (red) in the Golgi, near the nucleus (blue). Featured in the June 21, 2012, issue of Biomedical Beat. Mohanish Deshmukh View Media

Endoplasmic reticulum abnormalities

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Human cells with the gene that codes for the protein FIT2 deleted. Green indicates an endoplasmic reticulum (ER) resident protein. Michel Becuwe, Harvard University. View Media

HeLa cells

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Scanning electron micrograph of an apoptotic HeLa cell. Zeiss Merlin HR-SEM. National Center for Microscopy and Imaging Research View Media

Flu virus proteins during self-replication

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Influenza (flu) virus proteins in the act of self-replication. Viral nucleoprotein (blue) encapsidates [encapsulates] the RNA genome (green). Scripps Research Institute in La Jolla, CA View Media

Skin cancer cells (squamous cell carcinoma)

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This image shows the uncontrolled growth of cells in squamous cell carcinoma, the second most common form of skin cancer. If caught early, squamous cell carcinoma is usually not life-threatening. Markus Schober and Elaine Fuchs, The Rockefeller University View Media

Sleep and the fly brain

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In the top snapshots, the brain of a sleep-deprived fruit fly glows orange, marking high concentrations of a synaptic protein called Bruchpilot (BRP) involved in communication between neurons. Chiara Cirelli, University of Wisconsin-Madison View Media

Tex protein

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Model of a member from the Tex protein family, which is implicated in transcriptional regulation and highly conserved in eukaryotes and prokaryotes. New York Structural GenomiX Research Consortium, PSI View Media

Cytochrome structure with anticancer drug

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This image shows the structure of the CYP17A1 enzyme (ribbons colored from blue N-terminus to red C-terminus), with the associated heme colored black. Emily Scott, University of Kansas View Media

Human retinal organoid

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A replica of a human retina grown from stem cells. Kevin Eliceiri, University of Wisconsin-Madison. View Media

Measles virus proteins

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A cross section of the measles virus in which six proteins (enlarged on the outside of the virus) work together to infect cells. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Yeast cells responding to a glucose shortage

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These yeast cells were exposed to a glucose (sugar) shortage. Mike Henne, University of Texas Southwestern Medical Center. View Media

Bacterial cells migrating through the tissues of the squid light organ

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Vibrio fischeri cells (~ 2 mm), labeled with green fluorescent protein (GFP), passing through a very narrow bottleneck in the tissues (red) of the Hawaiian bobtail squid, Euprymna scolope Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

Mitochondria

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Bean-shaped mitochondria are cells' power plants. These organelles have their own DNA and replicate independently. The highly folded inner membranes are the site of energy generation. Judith Stoffer View Media

NCMIR Kidney Glomeruli

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Stained glomeruli in the kidney. The kidney is an essential organ responsible for disposing wastes from the body and for maintaining healthy ion levels in the blood. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Cultured cells

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This image of laboratory-grown cells was taken with the help of a scanning electron microscope, which yields detailed images of cell surfaces. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

PanC from M. tuberculosis

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Model of an enzyme, PanC, that is involved in the last step of vitamin B5 biosynthesis in Mycobacterium tuberculosis. PanC is essential for the growth of M. Mycobacterium Tuberculosis Center, PSI View Media

Mapping human genetic variation

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This map paints a colorful portrait of human genetic variation around the world. Noah Rosenberg and Martin Soave, University of Michigan View Media

Fruitful dyes

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These colorful, computer-generated ribbons show the backbone of a molecule that glows a fluorescent red. Roger Y. Tsien, University of California, San Diego View Media

Mapping metabolic activity

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Like a map showing heavily traveled roads, this mathematical model of metabolic activity inside an E. coli cell shows the busiest pathway in white. Albert-László Barabási, University of Notre Dame View Media

Introduction to Genome Editing Using CRISPR/Cas9

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Genome editing using CRISPR/Cas9 is a rapidly expanding field of scientific research with emerging applications in disease treatment, medical therapeutics and bioenergy, just to name a few. Janet Iwasa View Media

Snowflake yeast 3

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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View Media

DNA replication illustration (with labels)

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During DNA replication, each strand of the original molecule acts as a template for the synthesis of a new, complementary DNA strand. Crabtree + Company View Media

Color coding of the Drosophila brain - image

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This image results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View Media

Cluster analysis of mysterious protein

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Researchers use cluster analysis to study protein shape and function. Each green circle represents one potential shape of the protein mitoNEET. Patricia Jennings and Elizabeth Baxter, University of California, San Diego View Media

Activated mast cell surface

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A scanning electron microscope image of an activated mast cell. This image illustrates the interesting topography of the cell membrane, which is populated with receptors. Bridget Wilson, University of New Mexico View Media

Neural development

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Using techniques that took 4 years to design, a team of developmental biologists showed that certain proteins can direct the subdivision of fruit fly and chicken nervous system tissue into the regions Mieko Mizutani and Ethan Bier, University of California, San Diego, and Henk Roelink, University of Washington View Media

Fruit fly ovary

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In this image of a stained fruit fly ovary, the ovary is packed with immature eggs (with DNA stained blue). The cytoskeleton (in pink) is a collection of fibers that gives a cell shape and support. Crystal D. Rogers, Ph.D., University of California, Davis, School of Veterinary Medicine; and Mariano A. Loza-Coll, Ph.D., California State University, Northridge. View Media

Yeast art depicting the New York City skyline

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This skyline of New York City was created by “printing” nanodroplets containing yeast (Saccharomyces cerevisiae) onto a large plate. Each dot is a separate yeast colony. Michael Shen, Ph.D., Jasmine Temple, Leslie Mitchell, Ph.D., and Jef Boeke, Ph.D., New York University School of Medicine; and Nick Phillips, James Chuang, Ph.D., and Jiarui Wang, Johns Hopkins University. View Media