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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Vibrio bacteria

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Vibrio, a type (genus) of rod-shaped bacteria. Some Vibrio species cause cholera in humans. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

RNase A (1)

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A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Advanced Photon Source (APS) at Argonne National Lab

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The intense X-rays produced by synchrotrons such as the Advanced Photon Source are ideally suited for protein structure determination. Southeast Collaboratory for Structural Genomics View Media

Fruit fly ovary

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In this image of a stained fruit fly ovary, the ovary is packed with immature eggs (with DNA stained blue). The cytoskeleton (in pink) is a collection of fibers that gives a cell shape and support. Crystal D. Rogers, Ph.D., University of California, Davis, School of Veterinary Medicine; and Mariano A. Loza-Coll, Ph.D., California State University, Northridge. View Media

Mitochondria from rat heart muscle cell

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These mitochondria (red) are from the heart muscle cell of a rat. Mitochondria have an inner membrane that folds in many places (and that appears here as striations). National Center for Microscopy and Imaging Research View Media

Draper, shown in the fatbody of a Drosophila melanogaster larva

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The fly fatbody is a nutrient storage and mobilization organ akin to the mammalian liver. The engulfment receptor Draper (green) is located at the cell surface of fatbody cells. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View Media

Enzymes convert subtrates into products (with labels)

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Enzymes convert substrates into products very quickly. See image 2521 for an unlabeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Nociceptin/orphanin FQ peptide opioid receptor

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The receptor is shown bound to an antagonist, compound-24 Raymond Stevens, The Scripps Research Institute View Media

ATP Synthase

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Atomic model of the membrane region of the mitochondrial ATP synthase built into a cryo-EM map at 3.6 Å resolution. ATP synthase is the primary producer of ATP in aerobic cells. Bridget Carragher, <a href="http://nramm.nysbc.org/">NRAMM National Resource for Automated Molecular Microscopy</a> View Media

C. elegans trapped by carnivorous fungus

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Real-time footage of Caenorhabditis elegans, a tiny roundworm, trapped by a carnivorous fungus, Arthrobotrys dactyloides. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Aspirin (with labels)

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Acetylsalicylate (bottom) is the aspirin of today. Crabtree + Company View Media

G switch (with labels and stages)

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The G switch allows our bodies to respond rapidly to hormones. G proteins act like relay batons to pass messages from circulating hormones into cells. Crabtree + Company View Media

Human ES cells turn into insulin-producing cells

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Human embryonic stem cells were differentiated into cells like those found in the pancreas (blue), which give rise to insulin-producing cells (red). Eugene Brandon, ViaCyte, via CIRM View Media

Axolotl showing nervous system

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The head of an axolotl—a type of salamander—that has been genetically modified so that its developing nervous system glows purple and its Schwann cell nuclei appear light blue. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media

CRISPR Illustration Frame 3

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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media

Yeast cells responding to a glucose shortage

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These yeast cells were exposed to a glucose (sugar) shortage. Mike Henne, University of Texas Southwestern Medical Center. View Media

Cells keep their shape with actin filaments and microtubules

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This image shows a normal fibroblast, a type of cell that is common in connective tissue and frequently studied in research labs. James J. Faust and David G. Capco, Arizona State University View Media

Rhodopsin bound to visual arrestin

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Rhodopsin is a pigment in the rod cells of the retina (back of the eye). It is extremely light-sensitive, supporting vision in low-light conditions. Protein Data Bank. View Media

Mitochondria from rat heart muscle cell_2

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These mitochondria (brown) are from the heart muscle cell of a rat. Mitochondria have an inner membrane that folds in many places (and that appears here as striations). National Center for Microscopy and Imaging Research View Media

Bottles of warfarin

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In 2007, the FDA modified warfarin's label to indicate that genetic makeup may affect patient response to the drug. The widely used blood thinner is sold under the brand name Coumadin®. Alisa Machalek, NIGMS/NIH View Media

Insulin production and fat sensing in fruit flies

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Fourteen neurons (magenta) in the adult Drosophila brain produce insulin, and fat tissue sends packets of lipids to the brain via the lipoprotein carriers (green). Akhila Rajan, Fred Hutchinson Cancer Center View Media

Fruit fly retina 01

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Image showing rhabdomeres (red), the light-sensitive structures in the fruit fly retina, and rhodopsin-4 (blue), a light-sensing molecule. Hermann Steller, Rockefeller University View Media

Hair cells: the sound-sensing cells in the ear

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These cells get their name from the hairlike structures that extend from them into the fluid-filled tube of the inner ear. Henning Horn, Brian Burke, and Colin Stewart, Institute of Medical Biology, Agency for Science, Technology, and Research, Singapore View Media

Purkinje cells are one of the main cell types in the brain

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This image captures Purkinje cells (red), one of the main types of nerve cell found in the brain. Yinghua Ma and Timothy Vartanian, Cornell University, Ithaca, N.Y. View Media

Housekeeping cell illustration

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Cell mopping up. Judith Stoffer View Media

Bacteria shapes

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A colorized scanning electron micrograph of bacteria. Scanning electron microscopes allow scientists to see the three-dimensional surface of their samples. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

The 26S proteasome engages with a protein substrate

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The proteasome is a critical multiprotein complex in the cell that breaks down and recycles proteins that have become damaged or are no longer needed. Andreas Martin, HHMI View Media

PanC from M. tuberculosis

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Model of an enzyme, PanC, that is involved in the last step of vitamin B5 biosynthesis in Mycobacterium tuberculosis. PanC is essential for the growth of M. Mycobacterium Tuberculosis Center, PSI View Media

Interphase in Xenopus frog cells

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These images show frog cells in interphase. The cells are Xenopus XL177 cells, which are derived from tadpole epithelial cells. The microtubules are green and the chromosomes are blue. Claire Walczak, who took them while working as a postdoc in the laboratory of Timothy Mitchison. View Media

Math from the heart

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Watch a cell ripple toward a beam of light that turns on a movement-related protein. View Media

Motor neuron progenitors derived from human ES cells

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Motor neuron progenitors (green) were derived from human embryonic stem cells. Image and caption information courtesy of the California Institute for Regenerative Medicine. Hans Keirstead lab, University of California, Irvine, via CIRM View Media

dUTP pyrophosphatase from M. tuberculosis

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Model of an enzyme, dUTP pyrophosphatase, from Mycobacterium tuberculosis. Drugs targeted to this enzyme might inhibit the replication of the bacterium that causes most cases of tuberculosis. Mycobacterium Tuberculosis Center, PSI View Media

Cell eyes clock

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Cells keep time to know when to retire. Judith Stoffer View Media

Snowflake yeast 3

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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View Media

3D reconstruction of the Golgi apparatus in a pancreas cell

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Researchers used cryo-electron tomography (cryo-ET) to capture images of a rat pancreas cell that were then compiled and color-coded to produce a 3D reconstruction. Xianjun Zhang, University of Southern California. View Media

Developing fruit fly nerve cord

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The glial cells (black dots) and nerve cells (brown bands) in this developing fruit fly nerve cord formed normally despite the absence of the SPITZ protein, which blocks their impending suicide. Hermann Steller, Rockefeller University View Media

Cisternae maturation model

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Animation for the cisternae maturation model of Golgi transport. Judith Stoffer View Media

Hippocampal neuron in culture

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Hippocampal neuron in culture. Dendrites are green, dendritic spines are red and DNA in cell's nucleus is blue. Shelley Halpain, UC San Diego View Media

White Poppy (cropped)

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A cropped image of a white poppy. View poppy uncropped here 3424. Judy Coyle, Donald Danforth Plant Science Center View Media

Ion channels

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The body uses a variety of ion channels to transport small molecules across cell membranes. Judith Stoffer View Media

Xenopus laevis egg

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Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View Media

ATP synthase (with labels)

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The world's smallest motor, ATP synthase, generates energy for the cell. See image 2517 for an unlabeled version of this illustration. Crabtree + Company View Media

Mouse colon with gut bacteria

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A section of mouse colon with gut bacteria (center, in green) residing within a protective pocket. Sarkis K. Mazmanian, California Institute of Technology View Media

A molecular interaction network in yeast 1

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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View Media

Repairing DNA

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Like a watch wrapped around a wrist, a special enzyme encircles the double helix to repair a broken strand of DNA. Tom Ellenberger, Washington University School of Medicine View Media

ARTS triggers apoptosis

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Cell showing overproduction of the ARTS protein (red). ARTS triggers apoptosis, as shown by the activation of caspase-3 (green) a key tool in the cell's destruction. The nucleus is shown in blue. Hermann Steller, Rockefeller University View Media

Pathways: The Fascinating Cells of Research Organisms

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Learn how research organisms, such as fruit flies and mice, can help us understand and treat human diseases. National Institute of General Medical Sciences View Media

Neutrophil-like cells migrating in a microfluidic chip

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Neutrophil-like cells (blue) in a microfluidic chip preferentially migrating toward LTB4 over fMLP. Caroline Jones, University of Texas at Dallas. View Media

Neuron with labeled synapses

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In this image, recombinant probes known as FingRs (Fibronectin Intrabodies Generated by mRNA display) were expressed in a cortical neuron, where they attached fluorescent proteins to either PSD95 (gre Don Arnold and Richard Roberts, University of Southern California. View Media

Natcher Building 08

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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View Media