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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
RNA interference (with labels)
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RNA interference or RNAi is a gene-silencing process in which double-stranded RNAs trigger the destruction of specific RNAs. Crabtree + Company View MediaEpithelial cell migration
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High-resolution time lapse of epithelial (skin) cell migration and wound healing. It shows an image taken every 13 seconds over the course of almost 14 minutes. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaFluorescent C. elegans showing muscle and ribosomal protein
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C. elegans, a tiny roundworm, with a ribosomal protein glowing red and muscle fibers glowing green. Researchers used these worms to study a molecular pathway that affects aging. Jarod Rollins, Mount Desert Island Biological Laboratory. View MediaSpinal nerve cells
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Neurons (green) and glial cells from isolated dorsal root ganglia express COX-2 (red) after exposure to an inflammatory stimulus (cell nuclei are blue). Lawrence Marnett, Vanderbilt University View MediaBlood clots show their flex
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Blood clots stop bleeding, but they also can cause heart attacks and strokes. Eric Lee, University of Illinois at Urbana-Champaign View MediaAntibodies in silica honeycomb
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Antibodies are among the most promising therapies for certain forms of cancer, but patients must take them intravenously, exposing healthy tissues to the drug and increasing the risk of side effects. Chenghong Lei, Pacific Northwest National Laboratory & Karl Erik Hellstrom, University of Washington View MediaCell-like compartments from frog eggs 2
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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View MediaHydra 04
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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View MediaSponge
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Many of today's medicines come from products found in nature, such as this sponge found off the coast of Palau in the Pacific Ocean. Phil Baran, Scripps Research Institute View MediaLily mitosis 06
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaProteasome
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This fruit fly spermatid recycles various molecules, including malformed or damaged proteins. Sigi Benjamin-Hong, Rockefeller University View MediaQ fever bacteria in an infected cell
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This image shows Q fever bacteria (yellow), which infect cows, sheep, and goats around the world and can infect humans, as well. When caught early, Q fever can be cured with antibiotics. Robert Heinzen, Elizabeth Fischer, and Anita Mora, National Institute of Allergy and Infectious Diseases, National Institutes of Health View MediaBiopixels
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Bioengineers were able to coax bacteria to blink in unison on microfluidic chips. This image shows a small chip with about 500 blinking bacterial colonies or biopixels. Jeff Hasty Lab, UC San Diego View MediaProtein from Arabidopsis thaliana
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NMR solution structure of a plant protein that may function in host defense. This protein was expressed in a convenient and efficient wheat germ cell-free system. Center for Eukaryotic Structural Genomics View MediaEpithelial cells
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This image mostly shows normal cultured epithelial cells expressing green fluorescent protein targeted to the Golgi apparatus (yellow-green) and stained for actin (magenta) and DNA (cyan). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaMyelinated axons 2
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Top view of myelinated axons in a rat spinal root. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaMicroscopy image of bird-and-flower DNA origami
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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. Hao Yan, Arizona State University View MediaPrecise development in the fruit fly embryo
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This 2-hour-old fly embryo already has a blueprint for its formation, and the process for following it is so precise that the difference of just a few key molecules can change the plans. Thomas Gregor, Princeton University View MediaSpreading Cells 01
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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View MediaMitotic cell awaits chromosome alignment
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During mitosis, spindle microtubules (red) attach to chromosome pairs (blue), directing them to the spindle equator. View MediaBrains of sleep-deprived and well-rested fruit flies
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On top, the brain of a sleep-deprived fly glows orange because of Bruchpilot, a communication protein between brain cells. These bright orange brain areas are associated with learning. Chiara Cirelli, University of Wisconsin-Madison View MediaWhite Poppy (cropped)
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A cropped image of a white poppy. View poppy uncropped here 3424. Judy Coyle, Donald Danforth Plant Science Center View MediadUTP pyrophosphatase from M. tuberculosis
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Model of an enzyme, dUTP pyrophosphatase, from Mycobacterium tuberculosis. Drugs targeted to this enzyme might inhibit the replication of the bacterium that causes most cases of tuberculosis. Mycobacterium Tuberculosis Center, PSI View MediaYeast cells responding to a glucose shortage
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These yeast cells were exposed to a glucose (sugar) shortage. Mike Henne, University of Texas Southwestern Medical Center. View MediaHuman retinal organoid
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A replica of a human retina grown from stem cells. Kevin Eliceiri, University of Wisconsin-Madison. View MediaRecombinant DNA (with labels)
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To splice a human gene (in this case, the one for insulin) into a plasmid, scientists take the plasmid out of an E. Crabtree + Company View MediaAntibiotic-surviving bacteria
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Colonies of bacteria growing despite high concentrations of antibiotics. These colonies are visible both by eye, as seen on the left, and by bioluminescence imaging, as seen on the right. Paul Stoodley, The Ohio State University. View MediaTime-lapse video of floral pattern in a mixture of two bacterial species, Acinetobacter baylyi and Escherichia coli, grown on a semi-solid agar for 24 hours
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This time-lapse video shows the emergence of a flower-like pattern in a mixture of two bacterial species, motile Acinetobacter baylyi and non-motile Escherichia coli (green), that are gr L. Xiong et al, eLife 2020;9: e48885 View MediaSea urchin embryo 04
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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View MediaEarly life of a protein
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This illustration represents the early life of a protein—specifically, apomyoglobin—as it is synthesized by a ribosome and emerges from the ribosomal tunnel, which contains the newly formed protein's Silvia Cavagnero, University of Wisconsin, Madison View MediaCRISPR Illustration Frame 2
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaPlanarian stem cell colony
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Planarians are freshwater flatworms that have powerful abilities to regenerate their bodies, which would seem to make them natural model organisms in which to study stem cells. Peter Reddien, Whitehead Institute View MediaLarvae from the parasitic worm that causes schistosomiasis
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The parasitic worm that causes schistosomiasis hatches in water and grows up in a freshwater snail, as shown here. Bo Wang and Phillip A. Newmark, University of Illinois at Urbana-Champaign, 2013 FASEB BioArt winner View MediaThermotoga maritima and its metabolic network
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A combination of protein structures determined experimentally and computationally shows us the complete metabolic network of a heat-loving bacterium. View MediaHow cilia do the wave
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Thin, hair-like biological structures called cilia are tiny but mighty. Zvonimir Dogic, Brandeis University View MediaMulticolor STORM
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In 2006, scientists developed an optical microscopy technique enabling them to clearly see individual molecules within cells. In 2007, they took the technique, abbreviated STORM, a step further. Xiaowei Zhuang, Harvard University View MediaSuperconducting magnet
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Superconducting magnet for NMR research, from the February 2003 profile of Dorothee Kern in Findings. Mike Lovett View MediaPlant resistosome
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The research organism Arabidopsis thaliana forms a large molecular machine called a resistosome to fight off infections. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaQuorum-sensing inhibitor limits bacterial growth
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To simulate the consequences of disrupting bacterial cell-to-cell communication, called quorum sensing, in the crypts (small chambers within the colon), the researchers experimented with an inhibitor Minyoung Kevin Kim and Bonnie Bassler, Princeton University View MediaAlternative splicing
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Arranging exons in different patterns, called alternative splicing, enables cells to make different proteins from a single gene. Crabtree + Company View MediaFused, dicentric chromosomes
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This fused chromosome has two functional centromeres, shown as two sets of red and green dots. Beth A. Sullivan, Duke University View MediaHighlighted cells
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The cytoskeleton (green) and DNA (purple) are highlighed in these cells by immunofluorescence. Torsten Wittmann, Scripps Research Institute View MediaPlasma-Derived Membrane Vesicles
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This fiery image doesn’t come from inside a bubbling volcano. Instead, it shows animal cells caught in the act of making bubbles, or blebbing. Jeanne Stachowiak, University of Texas at Austin View MediaColorful cells
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Actin (purple), microtubules (yellow), and nuclei (green) are labeled in these cells by immunofluorescence. This image won first place in the Nikon 2003 Small World photo competition. Torsten Wittmann, Scripps Research Institute View MediaProtein folding video
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Proteins are long chains of amino acids. Each protein has a unique amino acid sequence. It is still a mystery how a protein folds into the proper shape based on its sequence. Theoretical and Computational Biophysics Group View MediaMitosis - metaphase
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A cell in metaphase during mitosis: The copied chromosomes align in the middle of the spindle. Judith Stoffer View MediaSeeing signaling protein activation in cells 01
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Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins, regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View MediaSnowflake yeast 2
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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View MediaIntracellular forces
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Force vectors computed from actin cytoskeleton flow. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View MediaDNA replication illustration (with labels)
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During DNA replication, each strand of the original molecule acts as a template for the synthesis of a new, complementary DNA strand. Crabtree + Company View Media