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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Human embryonic stem cells
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The center cluster of cells, colored blue, shows a colony of human embryonic stem cells. James Thomson, University of Wisconsin-Madison View MediaRNA interference (with labels)
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RNA interference or RNAi is a gene-silencing process in which double-stranded RNAs trigger the destruction of specific RNAs. Crabtree + Company View MediaInduced stem cells from adult skin 04
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The human skin cells pictured contain genetic modifications that make them pluripotent, essentially equivalent to embryonic stem cells. James Thomson, University of Wisconsin-Madison View MediaFat cells (red) and blood vessels (green)
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A mouse's fat cells (red) are shown surrounded by a network of blood vessels (green). Daniela Malide, National Heart, Lung, and Blood Institute, National Institutes of Health View MediaMyotonic dystrophy type 2 genetic defect
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Scientists revealed a detailed image of the genetic defect that causes myotonic dystrophy type 2 and used that information to design drug candidates to counteract the disease. Matthew Disney, Scripps Research Institute and Ilyas Yildirim, Northwestern University View MediaCatalase diversity
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Catalases are some of the most efficient enzymes found in cells. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaHen egg lysozyme (1)
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Crystals of hen egg lysozyme protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaCapillary protein crystallization robot
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This ACAPELLA robot for capillary protein crystallization grows protein crystals, freezes them, and centers them without manual intervention. Structural Genomics of Pathogenic Protozoa Consortium View MediaFruitful dyes
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These colorful, computer-generated ribbons show the backbone of a molecule that glows a fluorescent red. Roger Y. Tsien, University of California, San Diego View MediaDense tubular matrices in the peripheral endoplasmic reticulum (ER) 2
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Three-dimensional reconstruction of a tubular matrix in a thin section of the peripheral endoplasmic reticulum between the plasma membranes of the cell. Jennifer Lippincott-Schwartz, Howard Hughes Medical Institute Janelia Research Campus, Virginia View MediaPig trypsin (1)
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A crystal of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaAn insect tracheal cell delivers air to muscles
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Insects like the fruit fly use an elaborate network of branching tubes called trachea (green) to transport oxygen throughout their bodies. Jayan Nair and Maria Leptin, European Molecular Biology Laboratory, Heidelberg, Germany View MediaNatcher Building 08
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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View MediaVDAC-1 (3)
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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaLeading cells with light
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A blue laser beam turns on a protein that helps this human cancer cell move. Responding to the stimulus, the protein, called Rac1, first creates ruffles at the edge of the cell. Yi Wu, University of North Carolina View MediaFruit fly egg ooplasmic streaming
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Two fruit fly (Drosophila melanogaster) egg cells, one on each side of the central black line. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View MediaActivation energy (with labels)
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To become products, reactants must overcome an energy hill. See image 2525 for an unlabeled version of this illustration. Crabtree + Company View MediaQ fever bacteria in an infected cell
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This image shows Q fever bacteria (yellow), which infect cows, sheep, and goats around the world and can infect humans, as well. When caught early, Q fever can be cured with antibiotics. Robert Heinzen, Elizabeth Fischer, and Anita Mora, National Institute of Allergy and Infectious Diseases, National Institutes of Health View MediaMovements of myosin
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Inside the fertilized egg cell of a fruit fly, we see a type of myosin (related to the protein that helps muscles contract) made to glow by attaching a fluorescent protein. Victoria Foe, University of Washington View MediaPlanarian stem cell colony
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Planarians are freshwater flatworms that have powerful abilities to regenerate their bodies, which would seem to make them natural model organisms in which to study stem cells. Peter Reddien, Whitehead Institute View MediaCRISPR Illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaHuman skeletal muscle
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Cross section of human skeletal muscle. Image taken with a confocal fluorescent light microscope. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaCorrelative imaging by annotation with single molecules (CIASM) process
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These images illustrate a technique combining cryo-electron tomography and super-resolution fluorescence microscopy called correlative imaging by annotation with single molecules (CIASM). Peter Dahlberg, Stanford University. View MediaKupffer cell residing in the liver
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Kupffer cells appear in the liver during the early stages of mammalian development and stay put throughout life to protect liver cells, clean up old red blood cells, and regulate iron levels. Thomas Deerinck, National Center for Microscopy and Imaging Research, University of California, San Diego. View MediaMeasles virus proteins
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A cross section of the measles virus in which six proteins (enlarged on the outside of the virus) work together to infect cells. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaStudent overseeing protein cloning robot
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Student Christina Hueneke of the Midwest Center for Structural Genomics is overseeing a protein cloning robot. Midwest Center for Structural Genomics View MediaHIV, the AIDS virus, infecting a human cell
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This human T cell (blue) is under attack by HIV (yellow), the virus that causes AIDS. Seth Pincus, Elizabeth Fischer, and Austin Athman, National Institute of Allergy and Infectious Diseases, National Institutes of Health View MediaDNase
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Crystals of DNase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaWorm sperm
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To develop a system for studying cell motility in unnatrual conditions -- a microscope slide instead of the body -- Tom Roberts and Katsuya Shimabukuro at Florida State University disassembled and rec Tom Roberts, Florida State University View MediaVesicle traffic
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This illustration shows vesicle traffic inside a cell. Judith Stoffer View MediaHow a microtubule builds and deconstructs
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A microtubule, part of the cell's skeleton, builds and deconstructs. View MediaRibbon diagram of a cefotaxime-CCD-1 complex
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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View MediaA Bacillus subtilis biofilm grown in a Petri dish
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Bacterial biofilms are tightly knit communities of bacterial cells growing on, for example, solid surfaces, such as in water pipes or on teeth. Gürol Süel, UCSD View MediaActivated mast cell surface
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A scanning electron microscope image of an activated mast cell. This image illustrates the interesting topography of the cell membrane, which is populated with receptors. Bridget Wilson, University of New Mexico View MediaZebrafish embryo
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A zebrafish embryo showing its natural colors. Zebrafish have see-through eggs and embryos, making them ideal research organisms for studying the earliest stages of development. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaX-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 6
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View MediaFruit fly retina 02
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Section of a fruit fly retina showing the light-sensing molecules rhodopsin-5 (blue) and rhodopsin-6 (red). Hermann Steller, Rockefeller University View MediaLily mitosis 09
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaThe Proteasome: The Cell's Trash Processor in Action
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Our cells are constantly removing and recycling molecular waste. This video shows one way cells process their trash. View MediaKinases (with labels)
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Kinases are enzymes that add phosphate groups (red-yellow structures) to proteins (green), assigning the proteins a code. Crabtree + Company View MediaHen egg lysozyme (2)
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A crystal of hen egg lysozyme protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaMicrosporidia in roundworm 2
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Many disease-causing microbes manipulate their host’s metabolism and cells for their own ends. Keir Balla and Emily Troemel, University of California San Diego View MediaGolden gene chips
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A team of chemists and physicists used nanotechnology and DNA's ability to self-assemble with matching RNA to create a new kind of chip for measuring gene activity. Hao Yan and Yonggang Ke, Arizona State University View MediaO2 reacting with a flavin-dependent enzyme
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Department of Biological Chemistry, University of Michigan View MediaDeveloping zebrafish fin
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Originally from the waters of India, Nepal, and neighboring countries, zebrafish can now be found swimming in science labs (and home aquariums) throughout the world. Jessica Plavicki View MediaX-ray diffraction pattern from a crystallized cefotaxime-CCD-1 complex
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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View MediaKinesin moves cellular cargo
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A protein called kinesin (blue) is in charge of moving cargo around inside cells and helping them divide. Charles Sindelar, Yale University View MediaNucleolinus
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The nucleolinus is a cellular compartment that has been a lonely bystander in scientific endeavors. Mary Anne Alliegro, Marine Biological Laboratory View MediaStreptococcus bacteria
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Image of Streptococcus, a type (genus) of spherical bacteria that can colonize the throat and back of the mouth. Stroptococci often occur in pairs or in chains, as shown here. Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaHIV-1 virus in the colon
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A tomographic reconstruction of the colon shows the location of large pools of HIV-1 virus particles (in blue) located in the spaces between adjacent cells. Mark Ladinsky, California Institute of Technology View Media