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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

ATP synthase

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The world's smallest motor, ATP synthase, generates energy for the cell. See image 2518 for a labeled version of this illustration. Crabtree + Company View Media

RNase A (1)

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A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Multicolor STORM

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In 2006, scientists developed an optical microscopy technique enabling them to clearly see individual molecules within cells. In 2007, they took the technique, abbreviated STORM, a step further. Xiaowei Zhuang, Harvard University View Media

Hen egg lysozyme (2)

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A crystal of hen egg lysozyme protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

ATP synthase (with labels)

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The world's smallest motor, ATP synthase, generates energy for the cell. See image 2517 for an unlabeled version of this illustration. Crabtree + Company View Media

Natcher Building 08

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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View Media

The eye uses many layers of nerve cells to convert light into sight

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This image captures the many layers of nerve cells in the retina. The top layer (green) is made up of cells called photoreceptors that convert light into electrical signals to relay to the brain. Wei Li, National Eye Institute, National Institutes of Health View Media

Cas9 protein involved in the CRISPR gene-editing technology

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In the gene-editing tool CRISPR, a small strand of RNA identifies a specific chunk of DNA. Janet Iwasa View Media

Chromosomes after crossing over

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Duplicated pair of chromosomes have exchanged material. Judith Stoffer View Media

Chromosomes before crossing over

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Duplicated pair of chromosomes lined up and ready to cross over. Judith Stoffer View Media

Sphingolipid S1P1 receptor

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The receptor is shown bound to an antagonist, ML056. Raymond Stevens, The Scripps Research Institute View Media

Blinking bacteria

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Like a pulsing blue shower, E. coli cells flash in synchrony. Genes inserted into each cell turn a fluorescent protein on and off at regular intervals. Jeff Hasty, University of California, San Diego View Media

Correlative imaging by annotation with single molecules (CIASM) process

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These images illustrate a technique combining cryo-electron tomography and super-resolution fluorescence microscopy called correlative imaging by annotation with single molecules (CIASM). Peter Dahlberg, Stanford University. View Media

Cell cycle (with labels)

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Cells progress through a cycle that consists of phases for growth (G1, S, and G2) and division (M). Cells become quiescent when they exit this cycle (G0). Crabtree + Company View Media

Aspirin

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Acetylsalicylate (bottom) is the aspirin of today. Crabtree + Company View Media

RNA polymerase

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RNA polymerase (purple) is a complex enzyme at the heart of transcription. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Borrelia burgdorferi

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Borrelia burgdorferi is a spirochete, a class of long, slender bacteria that typically take on a coiled shape. Infection with this bacterium causes Lyme disease. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

Bacillus anthracis being killed

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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. John Alumasa, Keiler Laboratory, Pennsylvania State University View Media

Fruit fly ovaries

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Fruit fly (Drosophila melanogaster) ovaries with DNA shown in magenta and actin filaments shown in light blue. This image was captured using a confocal laser scanning microscope.
Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media

Natcher Building 07

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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View Media

Arachnoidiscus diatom

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An Arachnoidiscus diatom with a diameter of 190µm. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Bacterial cells aggregated above a light-organ pore of the Hawaiian bobtail squid

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The beating of cilia on the outside of the Hawaiian bobtail squid’s light organ concentrates Vibrio fischeri cells (green) present in the seawater into aggregates near the pore-containing tis Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

ARTS triggers apoptosis

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Cell showing overproduction of the ARTS protein (red). ARTS triggers apoptosis, as shown by the activation of caspase-3 (green) a key tool in the cell's destruction. The nucleus is shown in blue. Hermann Steller, Rockefeller University View Media

Tracking embryonic zebrafish cells

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To better understand cell movements in developing embryos, researchers isolated cells from early zebrafish embryos and grew them as clusters. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View Media

Lily mitosis 01

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A light microscope image shows the chromosomes, stained dark blue, in a dividing cell of an African globe lily (Scadoxus katherinae). Andrew S. Bajer, University of Oregon, Eugene View Media

Zinc levels in a plant leaf

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Zinc is required for the function of more than 300 enzymes, including those that help regulate gene expression, in various organisms including humans. Suzana Car, Dartmouth College View Media

Anthrax bacteria (green) being swallowed by an immune system cell

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Multiple anthrax bacteria (green) being enveloped by an immune system cell (purple). Anthrax bacteria live in soil and form dormant spores that can survive for decades. Camenzind G. Robinson, Sarah Guilman, and Arthur Friedlander, United States Army Medical Research Institute of Infectious Diseases View Media

Chang Shan

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For thousands of years, Chinese herbalists have treated malaria using Chang Shan, a root extract from a type of hydrangea that grows in Tibet and Nepal. Paul Schimmel Lab, Scripps Research Institute View Media

A molecular interaction network in yeast 2

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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View Media

Life in balance

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Mitosis creates cells, and apoptosis kills them. The processes often work together to keep us healthy. Judith Stoffer View Media

Circadian rhythms and the SCN

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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. NIGMS View Media

Bacterial cells aggregating above the light organ of the Hawaiian bobtail squid

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A light organ (~0.5 mm across) of a juvenile Hawaiian bobtail squid, Euprymna scolopes. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

Hen egg lysozyme (1)

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Crystals of hen egg lysozyme protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Neurons from human ES cells

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These neural precursor cells were derived from human embryonic stem cells. The neural cell bodies are stained red, and the nuclei are blue. Xianmin Zeng lab, Buck Institute for Age Research, via CIRM View Media

Immune cell attacks cell infected with a retrovirus

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T cells engulf and digest cells displaying markers (or antigens) for retroviruses, such as HIV. Kristy Whitehouse, science illustrator View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Dividing cell

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As this cell was undergoing cell division, it was imaged with two microscopy techniques: differential interference contrast (DIC) and confocal. The DIC view appears in blue and shows the entire cell. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media

Dynamin structure

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When a molecule arrives at a cell's outer membrane, the membrane creates a pouch around the molecule that protrudes inward. Josh Chappie, National Institute of Diabetes and Digestive and Kidney Diseases, NIH View Media

A molecular interaction network in yeast 1

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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View Media

Nociceptin/orphanin FQ peptide opioid receptor

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The receptor is shown bound to an antagonist, compound-24 Raymond Stevens, The Scripps Research Institute View Media

Scientists display X-ray diffraction pattern obtained with split X-ray beamline

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Scientists from Argonne National Laboratory's Advanced Photon Source (APS) display the first X-ray diffraction pattern obtained from a protein crystal using a split X-ray beam, the first of its kind a GM/CA Collaborative Access Team View Media

Cell division and cell death

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Two cells over a 2-hour period. The one on the bottom left goes through programmed cell death, also known as apoptosis. The one on the top right goes through cell division, also called mitosis. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media

Cell cycle wheel

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A typical animal cell cycle lasts roughly 24 hours, but depending on the type of cell, it can vary in length from less than 8 hours to more than a year. Most of the variability occurs in Gap1. Judith Stoffer View Media

Activation energy

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To become products, reactants must overcome an energy hill. See image 2526 for a labeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Wound healing in process

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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View Media

Mitosis and meiosis compared

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Meiosis is used to make sperm and egg cells. During meiosis, a cell's chromosomes are copied once, but the cell divides twice. Judith Stoffer View Media

Crab nerve cell

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Neuron from a crab showing the cell body (bottom), axon (rope-like extension), and growth cone (top right). Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

Nucleolus subcompartments spontaneously self-assemble 3

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What looks a little like distant planets with some mysterious surface features are actually assemblies of proteins normally found in the cell's nucleolus, a small but very important protein complex lo Nilesh Vaidya, Princeton University View Media

Nucleolus subcompartments spontaneously self-assemble 2

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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media

Sheep hemoglobin crystal

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A crystal of sheep hemoglobin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media