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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
H1N1 Influenza Virus
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CellPack image of the H1N1 influenza virus, with hemagglutinin and neuraminidase glycoproteins in green and red, respectively, on the outer envelope (white); matrix protein in gray, and ribonucleoprot Dr. Rommie Amaro, University of California, San Diego View MediaSnowflake DNA origami
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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. The image is featured on Biomedical Beat blog post Cool Images: A Holiday-Themed Collection. Hao Yan, Arizona State University View MediaAnti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 02
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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View MediaFruit fly retina 01
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Image showing rhabdomeres (red), the light-sensitive structures in the fruit fly retina, and rhodopsin-4 (blue), a light-sensing molecule. Hermann Steller, Rockefeller University View MediaHydra 04
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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View MediaFrom DNA to Protein
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Nucleotides in DNA are copied into RNA, where they are read three at a time to encode the amino acids in a protein. Many parts of a protein fold as the amino acids are strung together.Crabtree + Company View Media
Meiosis illustration (with labels)
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Meiosis is the process whereby a cell reduces its chromosomes from diploid to haploid in creating eggs or sperm. Crabtree + Company View MediaYeast cells entering mitosis
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Yeast cells entering mitosis, also known as cell division. The green and magenta dots are two proteins that play important roles in mitosis. They show where the cells will split. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View MediaBorrelia burgdorferi
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Borrelia burgdorferi is a spirochete, a class of long, slender bacteria that typically take on a coiled shape. Infection with this bacterium causes Lyme disease. Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaHawaiian bobtail squid
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An adult Hawaiian bobtail squid, Euprymna scolopes, swimming next to a submerged hand. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaChromosome fiber 01
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This microscopic image shows a chromatin fiber--a DNA molecule bound to naturally occurring proteins. Marc Green and Susan Forsburg, University of Southern California View MediaMicrotubule dynamics in real time
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Cytoplasmic linker protein (CLIP)-170 is a microtubule plus-end-tracking protein that regulates microtubule dynamics and links microtubule ends to different intracellular structures. Gary Borisy, Marine Biology Laboratory View MediaFruitful dyes
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These colorful, computer-generated ribbons show the backbone of a molecule that glows a fluorescent red. Roger Y. Tsien, University of California, San Diego View MediaPlasma-Derived Membrane Vesicles
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This fiery image doesn’t come from inside a bubbling volcano. Instead, it shows animal cells caught in the act of making bubbles, or blebbing. Jeanne Stachowiak, University of Texas at Austin View MediaBacteria in the mouse colon
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Image of the colon of a mouse mono-colonized with Bacteroides fragilis (red) residing within the crypt channel. The red staining is due to an antibody to B. Sarkis K. Mazmanian, California Institute of Technology View MediaMicroarray 01
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Microarrays, also called gene chips, are tools that let scientists track the activity of hundreds or thousands of genes simultaneously. Maggie Werner-Washburne, University of New Mexico, Albuquerque View MediaLab mice
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Many researchers use the mouse (Mus musculus) as a model organism to study mammalian biology. Bill Branson, National Institutes of Health View MediaCone cell
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The cone cell of the eye allows you to see in color. Appears in the NIGMS booklet Inside the Cell. Judith Stoffer View MediaHistones in chromatin
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Histone proteins loop together with double-stranded DNA to form a structure that resembles beads on a string. Crabtree + Company View MediaG switch (with labels and stages)
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The G switch allows our bodies to respond rapidly to hormones. G proteins act like relay batons to pass messages from circulating hormones into cells. Crabtree + Company View MediaEpigenetic code
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The "epigenetic code" controls gene activity with chemical tags that mark DNA (purple diamonds) and the "tails" of histone proteins (purple triangles). Crabtree + Company View MediaDicty fruit
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Dictyostelium discoideum is a microscopic amoeba. A group of 100,000 form a mound as big as a grain of sand. Featured in The New Genetics. View MediaDose response curves
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Dose-response curves determine how much of a drug (X-axis) causes a particular effect, or a side effect, in the body (Y-axis). Crabtree + Company View MediaCulex quinquefasciatus mosquito larvae
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Mosquito larvae with genes edited by CRISPR swimming in water. Valentino Gantz, University of California, San Diego. View MediaAspirin (with labels)
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Acetylsalicylate (bottom) is the aspirin of today. Crabtree + Company View MediaTrajectories of labeled cell receptors
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Trajectories of single molecule labeled cell surface receptors. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View MediaBacterial symbionts colonizing the crypts of a juvenile Hawaiian bobtail squid light organ
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A light organ (~0.5 mm across) of a Hawaiian bobtail squid, Euprymna scolopes, stained blue. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaHimastatin, 360-degree view
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A 360-degree view of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View MediaGolgi theories
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Two models for how material passes through the Golgi apparatus: the vesicular shuttle model and the cisternae maturation model. Judith Stoffer View MediaAntibodies in silica honeycomb
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Antibodies are among the most promising therapies for certain forms of cancer, but patients must take them intravenously, exposing healthy tissues to the drug and increasing the risk of side effects. Chenghong Lei, Pacific Northwest National Laboratory & Karl Erik Hellstrom, University of Washington View MediaCryo-ET cell cross-section visualizing insulin vesicles
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On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a color-coded, 3D version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View MediaMeasles virus proteins
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A cross section of the measles virus in which six proteins (enlarged on the outside of the virus) work together to infect cells. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaEarly life of a protein
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This illustration represents the early life of a protein—specifically, apomyoglobin—as it is synthesized by a ribosome and emerges from the ribosomal tunnel, which contains the newly formed protein's Silvia Cavagnero, University of Wisconsin, Madison View MediaSea urchin embryo 06
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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View MediaPathways: What is Basic Science?
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Learn about basic science, sometimes called “pure” or “fundamental” science, and how it contributes to the development of medical treatments. National Institute of General Medical Sciences View MediaBeta2-adrenergic receptor protein
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Crystal structure of the beta2-adrenergic receptor protein. The Stevens Laboratory, The Scripps Research Institute View MediaX-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View MediaFluorescence in situ hybridization (FISH) in mouse ES cells shows DNA interactions
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Researchers used fluorescence in situ hybridization (FISH) to confirm the presence of long range DNA-DNA interactions in mouse embryonic stem cells. Kathrin Plath, University of California, Los Angeles View MediaSpreading Cells- 02
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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View MediaAutomated crystal screening system
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Automated crystal screening systems such as the one shown here are becoming a common feature at synchrotron and other facilities where high-throughput crystal structure determination is being carried Southeast Collaboratory for Structural Genomics View MediaBacillus anthracis being killed
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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. Kenneth Keiler, Penn State University View MediaEpigenetic code (with labels)
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The "epigenetic code" controls gene activity with chemical tags that mark DNA (purple diamonds) and the "tails" of histone proteins (purple triangles). Crabtree + Company View MediaLily mitosis 05
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaVDAC-1 (1)
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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaQuorum-sensing inhibitor limits bacterial growth
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To simulate the consequences of disrupting bacterial cell-to-cell communication, called quorum sensing, in the crypts (small chambers within the colon), the researchers experimented with an inhibitor Minyoung Kevin Kim and Bonnie Bassler, Princeton University View MediaLeptospira bacteria
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Leptospira, shown here in green, is a type (genus) of elongated, spiral-shaped bacteria. Infection can cause Weil's disease, a kind of jaundice, in humans. Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaCells use bubble-like structures called vesicles to transport cargo
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Cells use bubble-like structures called vesicles (yellow) to import, transport, and export cargo and in cellular communication. A single cell may be filled with thousands of moving vesicles.Tatyana Svitkina, University of Pennsylvania View Media
Staphylococcus aureus aggregates on microstructured titanium surface
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Groups of Staphylococcus aureus bacteria (blue) attached to a microstructured titanium surface (green) that mimics an orthopedic implant used in joint replacement. Paul Stoodley, The Ohio State University. View MediaAutofluorescent xanthophores in zebrafish skin
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Pigment cells are cells that give skin its color. David Parichy, University of Washington View MediaBence Jones protein MLE
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A crystal of Bence Jones protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media