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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
TonB protein in gram-negative bacteria
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The green in this image highlights a protein called TonB, which is produced by many gram-negative bacteria, including those that cause typhoid fever, meningitis and dysentery. Phillip Klebba, Kansas State University View Media
Protein from E. faecalis
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X-ray structure of a DNA repair enzyme superfamily representative from the human gastrointestinal bacterium Enterococcus faecalis. Midwest Center for Structural Genomics View Media
Human retinal organoid
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A replica of a human retina grown from stem cells. Kevin Eliceiri, University of Wisconsin-Madison. View Media
Thymidylate synthase complementing protein from Thermotoga maritime
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A model of thymidylate synthase complementing protein from Thermotoga maritime. Joint Center for Structural Genomics, PSI View Media
Wreath-shaped protein from X. campestris
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Crystal structure of a protein with unknown function from Xanthomonas campestris, a plant pathogen. Eight copies of the protein crystallized to form a ring. Ken Schwinn and Sonia Espejon-Reynes, New York SGX Research Center for Structural Genomics View Media
From DNA to Protein (labeled)
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The genetic code in DNA is transcribed into RNA, which is translated into proteins with specific sequences. Crabtree + Company View Media
dUTP pyrophosphatase from M. tuberculosis
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Model of an enzyme, dUTP pyrophosphatase, from Mycobacterium tuberculosis. Drugs targeted to this enzyme might inhibit the replication of the bacterium that causes most cases of tuberculosis. Mycobacterium Tuberculosis Center, PSI View Media
PanB from M. tuberculosis (2)
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Model of an enzyme, PanB, from Mycobacterium tuberculosis, the bacterium that causes most cases of tuberculosis. This enzyme is an attractive drug target. Mycobacterium Tuberculosis Center, PSI-1 View Media
Mounting of protein crystals
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Automated methods using micromachined silicon are used at the Northeast Collaboratory for Structural Genomics to mount protein crystals for X-ray crystallography. The Northeast Collaboratory for Structural Genomics View Media
RNA interference (with labels)
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RNA interference or RNAi is a gene-silencing process in which double-stranded RNAs trigger the destruction of specific RNAs. Crabtree + Company View Media
Flu virus proteins during self-replication
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Influenza (flu) virus proteins in the act of self-replication. Viral nucleoprotein (blue) encapsidates [encapsulates] the RNA genome (green). Scripps Research Institute in La Jolla, CA View Media
The Proteasome: The Cell's Trash Processor in Action
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Our cells are constantly removing and recycling molecular waste. This video shows one way cells process their trash. View Media
Red blood cells
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This image of human red blood cells was obtained with the help of a scanning electron microscope, an instrument that uses a finely focused electron beam to yield detailed images of the surface of a sa Tina Weatherby Carvalho, University of Hawaii at Manoa View Media
Carbon building blocks (with examples)
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The arrangement of identical molecular components can make a dramatic difference. For example, carbon atoms can be arranged into dull graphite (left) or sparkly diamonds (right). Crabtree + Company View Media
Kappa opioid receptor
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The receptor is shown bound to an antagonist, JDTic. Raymond Stevens, The Scripps Research Institute View Media
Microscopy image of bird-and-flower DNA origami
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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. Hao Yan, Arizona State University View Media
PSI: from genes to structures
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The goal of the Protein Structure Initiative (PSI) is to determine the three-dimensional shapes of a wide range of proteins by solving the structures of representative members of each protein family f National Institute of General Medical Sciences View Media
Autofluorescent xanthophores in zebrafish skin
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Pigment cells are cells that give skin its color. David Parichy, University of Washington View Media
iPS cell facility at the Coriell Institute for Medical Research
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This lab space was designed for work on the induced pluripotent stem (iPS) cell collection, part of the NIGMS Human Genetic Cell Repository at the Coriell Institute for Medical Research. Courtney Sill, Coriell Institute for Medical Research View Media
Bond types (with labels)
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Ionic and covalent bonds hold molecules, like sodium chloride and chlorine gas, together. Hydrogen bonds among molecules, notably involving water, also play an important role in biology. Crabtree + Company View Media
A Bacillus subtilis biofilm grown in a Petri dish
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Bacterial biofilms are tightly knit communities of bacterial cells growing on, for example, solid surfaces, such as in water pipes or on teeth. Gürol Süel, UCSD View Media
Video of Calling Cards in a mouse brain
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The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. NIH Director's Blog View Media
Bacterial nanowire model
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A model of a Geobacter sulfurreducens nanowire created from cryo-electron microscopy images. Edward Egelman, University of Virginia. View Media
Zebrafish pigment cell
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Pigment cells are cells that give skin its color. David Parichy, University of Washington View Media
Petri dish
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The white circle in this image is a Petri dish, named for its inventor, Julius Richard Petri. H. Robert Horvitz and Dipon Ghosh, Massachusetts Institute of Technology. View Media
Pathways: The Fascinating Cells of Research Organisms
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Learn how research organisms, such as fruit flies and mice, can help us understand and treat human diseases. National Institute of General Medical Sciences View Media
Mandelate racemase from B. subtilis
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Model of the mandelate racemase enzyme from Bacillus subtilis, a bacterium commonly found in soil. New York Structural GenomiX Research Consortium, PSI View Media
Time-lapse video of floral pattern in a mixture of two bacterial species, Acinetobacter baylyi and Escherichia coli, grown on a semi-solid agar for 24 hours
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This time-lapse video shows the emergence of a flower-like pattern in a mixture of two bacterial species, motile Acinetobacter baylyi and non-motile Escherichia coli (green), that are gr L. Xiong et al, eLife 2020;9: e48885 View Media
Mouse retina close-up
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Keunyoung ("Christine") Kim National Center for Microscopy and Imaging Research (NCMIR) View Media
Skin cross-section
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Cross-section of skin anatomy shows layers and different tissue types. National Institutes of Health Medical Arts View Media
Natcher Building 06
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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View Media
CRISPR surveillance complex
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This image shows how the CRISPR surveillance complex is disabled by two copies of anti-CRISPR protein AcrF1 (red) and one AcrF2 (light green). NRAMM National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media
Xenopus laevis egg
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Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View Media
Stress Response in Cells
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Two highly stressed osteosarcoma cells are shown with a set of green droplet-like structures followed by a second set of magenta droplets. Julia F. Riley and Carlos A. Castañeda, Syracuse University View Media
Mitosis and meiosis compared
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Meiosis is used to make sperm and egg cells. During meiosis, a cell's chromosomes are copied once, but the cell divides twice. Judith Stoffer View Media
Developing zebrafish fin
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Originally from the waters of India, Nepal, and neighboring countries, zebrafish can now be found swimming in science labs (and home aquariums) throughout the world. Jessica Plavicki View Media
Cultured cells
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This image of laboratory-grown cells was taken with the help of a scanning electron microscope, which yields detailed images of cell surfaces. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media
Tracking cells in a gastrulating zebrafish embryo
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During development, a zebrafish embryo is transformed from a ball of cells into a recognizable body plan by sweeping convergence and extension cell movements. This process is called gastrulation. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View Media
Cryo-ET cross-section of a rat pancreas cell
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On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a 3D, color-coded version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View Media
Mouse colon with gut bacteria
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A section of mouse colon with gut bacteria (center, in green) residing within a protective pocket. Sarkis K. Mazmanian, California Institute of Technology View Media
V. Cholerae Biofilm
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Industrious V. cholerae bacteria (yellow) tend to thrive in denser biofilms (left) while moochers (red) thrive in weaker biofilms (right). View Media
Fruit fly retina 01
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Image showing rhabdomeres (red), the light-sensitive structures in the fruit fly retina, and rhodopsin-4 (blue), a light-sensing molecule. Hermann Steller, Rockefeller University View Media
Hen egg lysozyme (1)
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Crystals of hen egg lysozyme protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Bioluminescent imaging in adult zebrafish - lateral view
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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media
Colony of human ES cells
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A colony of human embryonic stem cells (light blue) grows on fibroblasts (dark blue). California Institute for Regenerative Medicine View Media
Z rings in bacterial division
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Lab-made liposomes contract where Z rings have gathered together and the constriction forces are greatest (arrows). Masaki Osawa, Duke University View Media
Mitosis - anaphase
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A cell in anaphase during mitosis: Chromosomes separate into two genetically identical groups and move to opposite ends of the spindle. Judith Stoffer View Media
Introduction to Genome Editing Using CRISPR/Cas9
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Genome editing using CRISPR/Cas9 is a rapidly expanding field of scientific research with emerging applications in disease treatment, medical therapeutics and bioenergy, just to name a few. Janet Iwasa View Media
Animal cell
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A typical animal cell, sliced open to reveal a cross-section of organelles. Judith Stoffer View Media
Streptococcus bacteria
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Image of Streptococcus, a type (genus) of spherical bacteria that can colonize the throat and back of the mouth. Stroptococci often occur in pairs or in chains, as shown here. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media
