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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Microtubule growth
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Map of microtubule growth rates. Rates are color coded. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View MediaAnti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 04
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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View MediaAntibiotic-surviving bacteria
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Colonies of bacteria growing despite high concentrations of antibiotics. These colonies are visible both by eye, as seen on the left, and by bioluminescence imaging, as seen on the right. Paul Stoodley, The Ohio State University. View MediaInduced stem cells from adult skin 02
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These cells are induced stem cells made from human adult skin cells that were genetically reprogrammed to mimic embryonic stem cells. James Thomson, University of Wisconsin-Madison View MediaVDAC-1 (1)
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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaMeasles virus
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A cross section of the measles virus in which six proteins work together to infect cells. The measles virus is extremely infectious; 9 out of 10 people exposed will contract the disease. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaMapping disease spread
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How far and fast an infectious disease spreads across a community depends on many factors, including transportation. These U.S. David Chrest, RTI International View MediaATP synthase (with labels)
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The world's smallest motor, ATP synthase, generates energy for the cell. See image 2517 for an unlabeled version of this illustration. Crabtree + Company View MediaFruit fly ovary_2
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A fruit fly ovary, shown here, contains as many as 20 eggs. Fruit flies are not merely tiny insects that buzz around overripe fruit--they are a venerable scientific tool. Denise Montell, University of California, Santa Barbara View MediaBeta-galactosidase montage showing cryo-EM improvement--transparent background
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Composite image of beta-galactosidase showing how cryo-EM’s resolution has improved dramatically in recent years. Older images to the left, more recent to the right. Veronica Falconieri, Sriram Subramaniam Lab, National Cancer Institute View MediaDeveloping zebrafish fin
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Originally from the waters of India, Nepal, and neighboring countries, zebrafish can now be found swimming in science labs (and home aquariums) throughout the world. Jessica Plavicki View MediaCells use bubble-like structures called vesicles to transport cargo
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Cells use bubble-like structures called vesicles (yellow) to import, transport, and export cargo and in cellular communication. A single cell may be filled with thousands of moving vesicles.Tatyana Svitkina, University of Pennsylvania View Media
Fruit fly ovarioles
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Three fruit fly (Drosophila melanogaster) ovarioles (yellow, blue, and magenta) with egg cells visible inside them. Ovarioles are tubes in the reproductive systems of female insects. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View MediaBioluminescent imaging in adult zebrafish - overhead view
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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View MediaO2 reacting with a flavin-dependent enzyme
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Department of Biological Chemistry, University of Michigan View MediaProtein involved in cell division from Mycoplasma pneumoniae
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Model of a protein involved in cell division from Mycoplasma pneumoniae. This model, based on X-ray crystallography, revealed a structural domain not seen before. Berkeley Structural Genomics Center, PSI View MediaHair cells: the sound-sensing cells in the ear
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These cells get their name from the hairlike structures that extend from them into the fluid-filled tube of the inner ear. Henning Horn, Brian Burke, and Colin Stewart, Institute of Medical Biology, Agency for Science, Technology, and Research, Singapore View MediaCell-like compartments from frog eggs 4
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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View MediaMyotonic dystrophy type 2 genetic defect
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Scientists revealed a detailed image of the genetic defect that causes myotonic dystrophy type 2 and used that information to design drug candidates to counteract the disease. Matthew Disney, Scripps Research Institute and Ilyas Yildirim, Northwestern University View MediaBone cancer cell
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This image shows an osteosarcoma cell with DNA in blue, energy factories (mitochondria) in yellow, and actin filaments—part of the cellular skeleton—in purple. Dylan Burnette and Jennifer Lippincott-Schwartz, NICHD View MediaConfocal microscopy of perineuronal nets in the brain 2
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The photo shows a confocal microscopy image of perineuronal nets (PNNs), which are specialized extracellular matrix (ECM) structures in the brain. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaCCP enzyme
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The enzyme CCP is found in the mitochondria of baker’s yeast. Scientists study the chemical reactions that CCP triggers, which involve a water molecule, iron, and oxygen. Protein Data Bank. View MediaBrains of sleep-deprived and well-rested fruit flies
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On top, the brain of a sleep-deprived fly glows orange because of Bruchpilot, a communication protein between brain cells. These bright orange brain areas are associated with learning. Chiara Cirelli, University of Wisconsin-Madison View MediaScientists display X-ray diffraction pattern obtained with split X-ray beamline
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Scientists from Argonne National Laboratory's Advanced Photon Source (APS) display the first X-ray diffraction pattern obtained from a protein crystal using a split X-ray beam, the first of its kind a GM/CA Collaborative Access Team View MediaSmooth ER
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The endoplasmic reticulum comes in two types: Rough ER is covered with ribosomes and prepares newly made proteins; smooth ER specializes in making lipids and breaking down toxic molecules. Judith Stoffer View MediaRetroviruses as fossils
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DNA doesn't leave a fossil record in stone, the way bones do. Instead, the DNA code itself holds the best evidence for organisms' genetic history. Emily Harrington, science illustrator View MediaC. elegans with blue and yellow lights in the background
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These microscopic roundworms, called Caenorhabditis elegans, lack eyes and the opsin proteins used by visual systems to detect colors. H. Robert Horvitz and Dipon Ghosh, Massachusetts Institute of Technology. View MediaDynamic cryo-EM model of the human transcription preinitiation complex
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Gene transcription is a process by which information encoded in DNA is transcribed into RNA. Eva Nogales, Berkeley Lab View MediaG switch
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The G switch allows our bodies to respond rapidly to hormones. See images 2537 and 2538 for labeled versions of this image. Crabtree + Company View MediaSnowflake DNA origami
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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. The image is featured on Biomedical Beat blog post Cool Images: A Holiday-Themed Collection. Hao Yan, Arizona State University View MediaCRISPR Illustration Frame 3
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaAutomated Worm Sorter - 4
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Georgia Tech associate professor Hang Lu holds a microfluidic chip that is part of a system that uses artificial intelligence and cutting-edge image processing to automatically examine large number of Georgia Tech/Gary Meek View MediaFruit fly spermatids
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Developing spermatids (precursors of mature sperm cells) begin as small, round cells and mature into long-tailed, tadpole-shaped ones. Lacramioara Fabian, The Hospital for Sick Children, Toronto, Canada View MediaTracking cells in a gastrulating zebrafish embryo
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During development, a zebrafish embryo is transformed from a ball of cells into a recognizable body plan by sweeping convergence and extension cell movements. This process is called gastrulation. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View MediaHydra 03
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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View MediaHuman Adenovirus
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The cryo-EM structure of human adenovirus D26 (HAdV-D26) at near atomic resolution (3.7 Å), determined in collaboration with the NRAMM facility*. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View MediaPig alpha amylase
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Crystals of porcine alpha amylase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaThree muscle fibers; the middle has a defect found in some neuromuscular diseases
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Of the three muscle fibers shown here, the one on the right and the one on the left are normal. The middle fiber is deficient a large protein called nebulin (blue). Christopher Pappas and Carol Gregorio, University of Arizona View MediaMouse sperm sections
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This transmission electron micrograph shows sections of mouse sperm tails, or flagella. Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaCulex quinquefasciatus mosquito larva
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A mosquito larva with genes edited by CRISPR. The red-orange glow is a fluorescent protein used to track the edits. Valentino Gantz, University of California, San Diego. View MediaMap of protein structures 02
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A global "map of the protein structure universe" indicating the positions of specific proteins. Berkeley Structural Genomics Center, PSI View MediaLeading cells with light
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A blue laser beam turns on a protein that helps this human cancer cell move. Responding to the stimulus, the protein, called Rac1, first creates ruffles at the edge of the cell. Yi Wu, University of North Carolina View MediaMolecular view of glutamatergic synapse
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This illustration highlights spherical pre-synaptic vesicles that carry the neurotransmitter glutamate. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaMapping brain differences
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This image of the human brain uses colors and shapes to show neurological differences between two people. Arthur Toga, University of California, Los Angeles View MediaInduced pluripotent stem cells from skin 02
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These induced pluripotent stem cells (iPS cells) were derived from a woman's skin. Blue show nuclei. Green show a protein found in iPS cells but not in skin cells (NANOG). Kathrin Plath lab, University of California, Los Angeles, via CIRM View MediaFruit fly ovary
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A fruit fly ovary, shown here, contains as many as 20 eggs. Fruit flies are not merely tiny insects that buzz around overripe fruit—they are a venerable scientific tool. Denise Montell, Johns Hopkins University and University of California, Santa Barbara View MediaCryo-ET cell cross-section visualizing insulin vesicles
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On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a color-coded, 3D version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View MediaHuman ES cells differentiating into neurons
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This image shows hundreds of human embryonic stem cells in various stages of differentiating into neurons. Guoping Fan lab, University of California, Los Angeles, via CIRM View MediaDopaminergic neurons derived from mouse embryonic stem cells
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These neurons are derived from mouse embryonic stem cells. Red shows cells making a protein called TH that is characteristic of the neurons that degenerate in Parkinson's disease. Yaping Sun, lab of Su Guo, University of California, San Francisco, via CIRM View MediaMolecular interactions
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This network map shows molecular interactions (yellow) associated with a congenital condition that causes heart arrhythmias and the targets for drugs that alter these interactions (red and blue). Ravi Iyengar, Mount Sinai School of Medicine View Media