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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Vimentin in a quail embryo

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Video of high-resolution confocal images depicting vimentin immunofluorescence (green) and nuclei (blue) at the edge of a quail embryo yolk. Andrés Garcia, Georgia Tech View Media

Cascade reaction promoted by water

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This illustration of an epoxide-opening cascade promoted by water emulates the proposed biosynthesis of some of the Red Tide toxins. Tim Jamison, Massachusetts Institute of Technology View Media

Flagellated bacterial cells

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Vibrio fischeri (2 mm in length) is the exclusive symbiotic partner of the Hawaiian bobtail squid, Euprymna scolopes. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

Dimeric ferredoxin-like protein from an unidentified marine microbe

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This is the first structure of a protein derived from the metagenomic sequences collected during the Sorcerer II Global Ocean Sampling project. Joint Center for Structural Genomics View Media

Plasma membrane (with labels)

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The plasma membrane is a cell's protective barrier. See image 2523 for an unlabeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Scanning electron microscopy of the ECM on the surface of a calf muscle

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This image shows the extracellular matrix (ECM) on the surface of a soleus (lower calf) muscle in light brown and blood vessels in pink. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

RNA interference

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RNA interference or RNAi is a gene-silencing process in which double-stranded RNAs trigger the destruction of specific RNAs. Crabtree + Company View Media

Podocytes from a chronically diseased kidney

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This scanning electron microscope (SEM) image shows podocytes--cells in the kidney that play a vital role in filtering waste from the bloodstream--from a patient with chronic kidney disease. Olga Troyanskaya, Princeton University and Matthias Kretzler, University of Michigan View Media

Protein crystals

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Structural biologists create crystals of proteins, shown here, as a first step in a process called X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Structure of amyloid-forming prion protein

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This structure from an amyloid-forming prion protein shows one way beta sheets can stack. Douglas Fowler, University of Washington View Media

C. elegans with blue and yellow lights in the background

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These microscopic roundworms, called Caenorhabditis elegans, lack eyes and the opsin proteins used by visual systems to detect colors. H. Robert Horvitz and Dipon Ghosh, Massachusetts Institute of Technology. View Media

Sepsis Infographic

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Sepsis is the body’s overactive and extreme response to an infection. More than 1.7 million people get sepsis each year in the United States. National Institute of General Medical Sciences View Media

Protective membrane and membrane proteins of the dengue virus visualized with cryo-EM

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Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View Media

Adult and juvenile Hawaiian bobtail squids

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An adult Hawaiian bobtail squid, Euprymna scolopes, (~4 cm) surrounded by newly hatched juveniles (~2 mm) in a bowl of seawater.
Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

Cell-like compartments emerging from scrambled frog eggs

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Cell-like compartments spontaneously emerge from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 4

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Smooth muscle from human ES cells

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These smooth muscle cells were derived from human embryonic stem cells. The nuclei are stained blue, and the proteins of the cytoskeleton are stained green. Alexey Terskikh lab, Burnham Institute for Medical Research, via CIRM View Media

HeLa cells

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Multiphoton fluorescence image of HeLa cells with cytoskeletal microtubules (magenta) and DNA (cyan). Nikon RTS2000MP custom laser scanning microscope. National Center for Microscopy and Imaging Research (NCMIR) View Media

Misfolded proteins within in the mitochondria

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Misfolded proteins (green) within mitochondria (red). Related to video 5877. Rong Li rong@jhu.edu Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA. View Media

Spreading Cells 01

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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View Media

A multicolored fish scale 2

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Each of the tiny colored specs in this image is a cell on the surface of a fish scale. Chen-Hui Chen and Kenneth Poss, Duke University View Media

Histones in chromatin

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Histone proteins loop together with double-stranded DNA to form a structure that resembles beads on a string. Crabtree + Company View Media

Building blocks and folding of proteins

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Proteins are made of amino acids hooked end-to-end like beads on a necklace. To become active, proteins must twist and fold into their final, or "native," conformation. Crabtree + Company View Media

Relapsing fever bacterium (gray) and red blood cells

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Relapsing fever is caused by a bacterium and transmitted by certain soft-bodied ticks or body lice. The disease is seldom fatal in humans, but it can be very serious and prolonged. NIAID View Media

Transient receptor potential channel TRPV5

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A 3D reconstruction of a transient receptor potential channel called TRPV5 that was created based on cryo-electron microscopy images. Vera Moiseenkova-Bell, University of Pennsylvania. View Media

Microsporidia in roundworm 2

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Many disease-causing microbes manipulate their host’s metabolism and cells for their own ends. Keir Balla and Emily Troemel, University of California San Diego View Media

Single-cell “radios” video

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Individual cells are color-coded based on their identity and signaling activity using a protein circuit technology developed by the Coyle Lab. Scott Coyle, University of Wisconsin-Madison. View Media

Fruit fly embryo

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Cells in an early-stage fruit fly embryo, showing the DIAP1 protein (pink), an inhibitor of apoptosis. Hermann Steller, Rockefeller University View Media

Fruit fly spermatids

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Developing spermatids (precursors of mature sperm cells) begin as small, round cells and mature into long-tailed, tadpole-shaped ones. Lacramioara Fabian, The Hospital for Sick Children, Toronto, Canada View Media

Human ES cells turn into insulin-producing cells

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Human embryonic stem cells were differentiated into cells like those found in the pancreas (blue), which give rise to insulin-producing cells (red). Eugene Brandon, ViaCyte, via CIRM View Media

Blood clots show their flex

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Blood clots stop bleeding, but they also can cause heart attacks and strokes. Eric Lee, University of Illinois at Urbana-Champaign View Media

Cryo-electron microscopy of the dengue virus showing protective membrane and membrane proteins

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Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View Media

Autofluorescent xanthophores in zebrafish skin

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Pigment cells are cells that give skin its color. David Parichy, University of Washington View Media

Network diagram of genes, cellular components and processes (labeled)

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This image shows the hierarchical ontology of genes, cellular components and processes derived from large genomic datasets. From Dutkowski et al. Janusz Dutkowski and Trey Ideker, University of California, San Diego View Media

Zebrafish pigment cell

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Pigment cells are cells that give skin its color. David Parichy, University of Washington View Media

NCMIR Intestine-1

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The small intestine is where most of our nutrients from the food we eat are absorbed into the bloodstream. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

A Bacillus subtilis biofilm grown in a Petri dish

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Bacterial biofilms are tightly knit communities of bacterial cells growing on, for example, solid surfaces, such as in water pipes or on teeth. Gürol Süel, UCSD View Media

Rotavirus structure

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This image shows a computer-generated, three-dimensional map of the rotavirus structure. This virus infects humans and other animals and causes severe diarrhea in infants and young children. Bridget Carragher, The Scripps Research Institute, La Jolla, CA View Media

Neural circuits in worms similar to those in humans

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Green and yellow fluorescence mark the processes and cell bodies of some C. elegans neurons. Shawn Xu, University of Michigan View Media

Electrostatic map of the adeno-associated virus with scale

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The new highly efficient parallelized DelPhi software was used to calculate the potential map distribution of an entire virus, the adeno-associated virus, which is made up of more than 484,000 atoms. Emil Alexov, Clemson University View Media

Nucleotides make up DNA (with labels)

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DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule, and the sugar molecule deoxyribose. Crabtree + Company View Media

Fruit fly brain responds to adipokines

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Drosophila adult brain showing that an adipokine (fat hormone) generates a response from neurons (aqua) and regulates insulin-producing neurons (red).
Akhila Rajan, Fred Hutchinson Cancer Center View Media

Zebrafish head vasculature

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A zebrafish head with blood vessels shown in purple. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media

Natcher Building 07

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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View Media

mDia1 antibody staining-01

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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View Media

Disease-susceptible Arabidopsis leaf

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This is a magnified view of an Arabidopsis thaliana leaf after several days of infection with the pathogen Hyaloperonospora arabidopsidis. Jeff Dangl, University of North Carolina, Chapel Hill View Media

CRISPR

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RNA incorporated into the CRISPR surveillance complex is positioned to scan across foreign DNA. Cryo-EM density from a 3Å reconstruction is shown as a yellow mesh. NRAMM National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media

Introns

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Genes are often interrupted by stretches of DNA (introns, blue) that do not contain instructions for making a protein. Crabtree + Company View Media

Yeast art depicting the New York City skyline

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This skyline of New York City was created by “printing” nanodroplets containing yeast (Saccharomyces cerevisiae) onto a large plate. Each dot is a separate yeast colony. Michael Shen, Ph.D., Jasmine Temple, Leslie Mitchell, Ph.D., and Jef Boeke, Ph.D., New York University School of Medicine; and Nick Phillips, James Chuang, Ph.D., and Jiarui Wang, Johns Hopkins University. View Media

Bond types (with labels)

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Ionic and covalent bonds hold molecules, like sodium chloride and chlorine gas, together. Hydrogen bonds among molecules, notably involving water, also play an important role in biology. Crabtree + Company View Media