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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Microsporidia in roundworm 3

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Many disease-causing microbes manipulate their host’s metabolism and cells for their own ends. Keir Balla and Emily Troemel, University of California San Diego View Media

Heart muscle with reprogrammed skin cells

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Skins cells were reprogrammed into heart muscle cells. The cells highlighted in green are remaining skin cells. Red indicates a protein that is unique to heart muscle. Deepak Srivastava, Gladstone Institute of Cardiovascular Disease, via CIRM View Media

Lily mitosis 09

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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media

Ubiquitin-fold modifier 1 from C. elegans

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Solution NMR structure of protein target WR41 (left) from C. elegans. Northeast Structural Genomics Consortium View Media

Misfolded proteins in mitochondria, 3-D video

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Three-dimensional image of misfolded proteins (green) within mitochondria (red). Related to image 5878. Rong Li, Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University View Media

Abnormal, spiky fibroblast

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This is a fibroblast, a connective tissue cell that plays an important role in wound healing. Normal fibroblasts have smooth edges. Praveen Suraneni, Stowers Institute for Medical Research, Kansas City, Mo. View Media

Lily mitosis 02

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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media

Regenerating lizard tail

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The interior of a regenerating lizard tail 14 days after the original tail was amputated. Thomas Lozito, University of Southern California. View Media

Hydra 03

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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View Media

Serum albumin structure 3

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Serum albumin (SA) is the most abundant protein in the blood plasma of mammals. SA has a characteristic heart-shape structure and is a highly versatile protein. Wladek Minor, University of Virginia View Media

Mouse embryo showing Smad4 protein

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This eerily glowing blob isn't an alien or a creature from the deep sea--it's a mouse embryo just eight and a half days old. The green shell and core show a protein called Smad4. Kenneth Zaret, Fox Chase Cancer Center View Media

Finding one bug

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A nanometer-sized biosensor can detect a single deadly bacterium in tainted ground beef. How? Weihong Tan, University of Florida in Gainesville View Media

Activated mast cell surface

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A scanning electron microscope image of an activated mast cell. This image illustrates the interesting topography of the cell membrane, which is populated with receptors. Bridget Wilson, University of New Mexico View Media

Highlighted cells

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The cytoskeleton (green) and DNA (purple) are highlighed in these cells by immunofluorescence. Torsten Wittmann, Scripps Research Institute View Media

Pathways: The Fascinating Cells of Research Organisms

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Learn how research organisms, such as fruit flies and mice, can help us understand and treat human diseases. National Institute of General Medical Sciences View Media

Microsporidia in roundworm 1

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Many disease-causing microbes manipulate their host’s metabolism and cells for their own ends. Keir Balla and Emily Troemel, University of California San Diego View Media

Planarian stem cell colony

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Planarians are freshwater flatworms that have powerful abilities to regenerate their bodies, which would seem to make them natural model organisms in which to study stem cells. Peter Reddien, Whitehead Institute View Media

Jellyfish, viewed with ZEISS Lightsheet Z.1 microscope

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Jellyfish are especially good models for studying the evolution of embryonic tissue layers. Despite being primitive, jellyfish have a nervous system (stained green here) and musculature (red). Helena Parra, Pompeu Fabra University, Spain View Media

NCMIR kidney-1

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Stained kidney tissue. The kidney is an essential organ responsible for disposing wastes from the body and for maintaining healthy ion levels in the blood. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Scanning electron microscopy of the ECM on the surface of a calf muscle

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This image shows the extracellular matrix (ECM) on the surface of a soleus (lower calf) muscle in light brown and blood vessels in pink. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Early development in Arabidopsis

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Early on, this Arabidopsis plant embryo picks sides: While one end will form the shoot, the other will take root underground. Zachery R. Smith, Jeff Long lab at the Salk Institute for Biological Studies View Media

CCP enzyme

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The enzyme CCP is found in the mitochondria of baker’s yeast. Scientists study the chemical reactions that CCP triggers, which involve a water molecule, iron, and oxygen. Protein Data Bank. View Media

Dividing yeast cells with spindle pole bodies and contractile rings

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During cell division, spindle pole bodies (glowing dots) move toward the ends of yeast cells to separate copied genetic information. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media

Shiga toxin

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E. coli bacteria normally live harmlessly in our intestines, but some cause disease by making toxins. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Sea urchin embryo 05

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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View Media

Vesicle traffic

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This illustration shows vesicle traffic inside a cell. Judith Stoffer View Media

Transcription factor Sox17 controls embryonic development of certain internal organs

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During embryonic development, transcription factors (proteins that regulate gene expression) govern the differentiation of cells into separate tissues and organs. James M. Wells, Cincinnati Children's Hospital Medical Center View Media

HIV-1 virus in the colon

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A tomographic reconstruction of the colon shows the location of large pools of HIV-1 virus particles (in blue) located in the spaces between adjacent cells. Mark Ladinsky, California Institute of Technology View Media

Z rings in bacterial division

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Lab-made liposomes contract where Z rings have gathered together and the constriction forces are greatest (arrows). Masaki Osawa, Duke University View Media

Cytonemes in developing fruit fly cells

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Scientists have long known that multicellular organisms use biological molecules produced by one cell and sensed by another to transmit messages that, for instance, guide proper development of organs Sougata Roy, University of California, San Francisco View Media

Circadian rhythm (with labels)

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The human body keeps time with a master clock called the suprachiasmatic nucleus or SCN. Crabtree + Company View Media

Protein purification facility

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The Center for Eukaryotic Structural Genomics protein purification facility is responsible for purifying all recombinant proteins produced by the center. Center for Eukaryotic Structural Genomics View Media

Mouse cerebellum in pink and blue

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The cerebellum is the brain's locomotion control center. Found at the base of your brain, the cerebellum is a single layer of tissue with deep folds like an accordion. National Center for Microscopy and Imaging Research (NCMIR) View Media

Plasma membrane

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The plasma membrane is a cell's protective barrier. See image 2524 for a labeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

HeLa cells

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Scanning electron micrograph of an apoptotic HeLa cell. Zeiss Merlin HR-SEM. National Center for Microscopy and Imaging Research View Media

Induced pluripotent stem cells from skin 02

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These induced pluripotent stem cells (iPS cells) were derived from a woman's skin. Blue show nuclei. Green show a protein found in iPS cells but not in skin cells (NANOG). Kathrin Plath lab, University of California, Los Angeles, via CIRM View Media

NCMIR human spinal nerve

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Spinal nerves are part of the peripheral nervous system. They run within the spinal column to carry nerve signals to and from all parts of the body. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Honeybee brain

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Insect brains, like the honeybee brain shown here, are very different in shape from human brains. Gene Robinson, University of Illinois at Urbana-Champaign. View Media

Color-coded chromosomes

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By mixing fluorescent dyes like an artist mixes paints, scientists are able to color code individual chromosomes. Anna Jauch, Institute of Human Genetics, Heidelberg, Germany View Media

Neurons from human ES cells 02

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These neurons were derived from human embryonic stem cells. The neural cell bodies with axonal projections are visible in red, and the nuclei in blue. Xianmin Zeng lab, Buck Institute for Age Research, via CIRM View Media

Cytoscape network diagram 1

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Molecular biologists are increasingly relying on bioinformatics software to visualize molecular interaction networks and to integrate these networks with data such as gene expression profiles. Keiichiro Ono, Trey Ideker lab, University of California, San Diego View Media

Panorama view of golden mitochondria

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Mitochondria are the powerhouses of the cells, generating the energy the cells need to do their tasks and to stay alive. Torsten Wittmann, University of California, San Francisco View Media

Biofilm blocking fluid flow

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This time-lapse movie shows that bacterial communities called biofilms can create blockages that prevent fluid flow in devices such as stents and catheters over a period of about 56 hours. Bonnie Bassler, Princeton University View Media

Brain cells in the hippocampus

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Hippocampal cells in culture with a neuron in green, showing hundreds of the small protrusions known as dendritic spines. Shelley Halpain, UC San Diego View Media

VDAC video 03

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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media

Coronavirus spike protein structure

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Coronaviruses are enveloped viruses responsible for 30 percent of mild respiratory infections and atypical deadly pneumonia in humans worldwide. Melody Campbell, UCSF View Media

Yeast cells with Fimbrin Fim1

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Yeast cells with the protein Fimbrin Fim1 shown in magenta. This protein plays a role in cell division. This image was captured using wide-field microscopy with deconvolution.
Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media

Peripheral nerve cells derived from ES cells

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Peripheral nerve cells made from human embryonic stem cell-derived neural crest stem cells. Stephen Dalton, University of Georgia View Media

Small blood vessels in a mouse retina

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Blood vessels at the back of the eye (retina) are used to diagnose glaucoma and diabetic eye disease. They also display characteristic changes in people with high blood pressure. National Center for Microscopy and Imaging Research View Media

Chromatin in human tenocyte

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The nucleus of a degenerating human tendon cell, also known as a tenocyte. It has been color-coded based on the density of chromatin—a substance made up of DNA and proteins. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media