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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Movie of the 19S proteasome subunit processing a protein substrate
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The proteasome is a critical multiprotein complex in the cell that breaks down and recycles proteins that have become damaged or are no longer needed. Andreas Martin, HHMI View Media
CRISPR Illustration Frame 4
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
Chromosomes before crossing over
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Duplicated pair of chromosomes lined up and ready to cross over. Judith Stoffer View Media
Pig trypsin (3)
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Crystals of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Yeast cells with Fimbrin Fim1
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Yeast cells with the protein Fimbrin Fim1 shown in magenta. This protein plays a role in cell division. This image was captured using wide-field microscopy with deconvolution.Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media
Bacteria working to eat
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Gram-negative bacteria perform molecular acrobatics just to eat. Because they're encased by two membranes, they must haul nutrients across both. Emad Tajkhorshid, University of Illinois at Urbana-Champaign View Media
Protein kinases as cancer chemotherapy targets
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Protein kinases—enzymes that add phosphate groups to molecules—are cancer chemotherapy targets because they play significant roles in almost all aspects of cell function, are tightly regulated, and co Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media
Mitosis - interphase
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A cell in interphase, at the start of mitosis: Chromosomes duplicate, and the copies remain attached to each other. Judith Stoffer View Media
Transmission electron microscopy of coronary artery wall with elastin-rich ECM pseudocolored in light brown
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Elastin is a fibrous protein in the extracellular matrix (ECM). It is abundant in artery walls like the one shown here. As its name indicates, elastin confers elasticity. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Fluorescent microscopy of kidney tissue--close-up
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This photograph of kidney tissue, taken using fluorescent light microscopy, shows a close-up view of part of image 3723. Tom Deerinck , National Center for Microscopy and Imaging Research View Media
Wound healing in process
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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View Media
Bacteriophage P22 capsid
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Cryo-electron microscopy (cryo-EM) has the power to capture details of proteins and other small biological structures at the molecular level. This image shows proteins in the capsid, or outer co Dr. Wah Chiu, Baylor College of Medicine View Media
Life of an AIDS virus (with labels)
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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View Media
Human endoplasmic reticulum membrane protein complex
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A 3D model of the human endoplasmic reticulum membrane protein complex (EMC) that identifies its nine essential subunits. Rebecca Voorhees, California Institute of Technology. View Media
Cellular traffic
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Like tractor-trailers on a highway, small sacs called vesicles transport substances within cells. This image tracks the motion of vesicles in a living cell. Alexey Sharonov and Robin Hochstrasser, University of Pennsylvania View Media
Research mentor and student
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A research mentor (Lori Eidson) and student (Nina Waldron, on the microscope) were 2009 members of the BRAIN (Behavioral Research Advancements In Neuroscience) program at Georgia State University in A Elizabeth Weaver, Georgia State University View Media
Cell division phases in Xenopus frog cells
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These images show three stages of cell division in Xenopus XL177 cells, which are derived from tadpole epithelial cells. They are (from top): metaphase, anaphase and telophase. Claire Walczak, who took them while working as a postdoc in the laboratory of Timothy Mitchison View Media
Nucleolus subcompartments spontaneously self-assemble 2
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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media
Protein map
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Network diagram showing a map of protein-protein interactions in a yeast (Saccharomyces cerevisiae) cell. This cluster includes 78 percent of the proteins in the yeast proteome. Hawoong Jeong, KAIST, Korea View Media
Oligoendopeptidase F from B. stearothermophilus
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Crystal structure of oligoendopeptidase F, a protein slicing enzyme from Bacillus stearothermophilus, a bacterium that can cause food products to spoil. Accelerated Technologies Center for Gene to 3D Structure/Midwest Center for Structural Genomics View Media
Telomerase illustration
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Reactivating telomerase in our cells does not appear to be a good way to extend the human lifespan. Cancer cells reactivate telomerase. Judith Stoffer View Media
Diversity oriented synthesis: generating skeletal diversity using folding processes
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This 1 1/2-minute video animation was produced for chemical biologist Stuart Schreiber's lab page. The animation shows how diverse chemical structures can be produced in the lab. Eric Keller View Media
Polarized cells- 02
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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View Media
Bond types
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Ionic and covalent bonds hold molecules, like sodium chloride and chlorine gas, together. Hydrogen bonds among molecules, notably involving water, also play an important role in biology. Crabtree + Company View Media
ATP Synthase
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Atomic model of the membrane region of the mitochondrial ATP synthase built into a cryo-EM map at 3.6 Å resolution. ATP synthase is the primary producer of ATP in aerobic cells. Bridget Carragher, <a href="http://nramm.nysbc.org/">NRAMM National Resource for Automated Molecular Microscopy</a> View Media
Trp_RS - tryptophanyl tRNA-synthetase family of enzymes
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This image represents the structure of TrpRS, a novel member of the tryptophanyl tRNA-synthetase family of enzymes. View Media
Dimeric association of receptor-type tyrosine-protein phosphatase
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Model of the catalytic portion of an enzyme, receptor-type tyrosine-protein phosphatase from humans. The enzyme consists of two identical protein subunits, shown in blue and green. New York Structural GenomiX Research Consortium, PSI View Media
Introns
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Genes are often interrupted by stretches of DNA (introns, blue) that do not contain instructions for making a protein. Crabtree + Company View Media
Induced stem cells from adult skin 02
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These cells are induced stem cells made from human adult skin cells that were genetically reprogrammed to mimic embryonic stem cells. James Thomson, University of Wisconsin-Madison View Media
Nucleosome
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Like a strand of white pearls, DNA wraps around an assembly of special proteins called histones (colored) to form the nucleosome, a structure responsible for regulating genes and condensing DNA strand Karolin Luger, Colorado State University View Media
Cell division with late aligning chromosomes
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This video shows an instance of abnormal mitosis where chromosomes are late to align. Gary Gorbsky, Oklahoma Medical Research Foundation View Media
Bacillus anthracis being killed
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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. Kenneth Keiler, Penn State University View Media
VDAC-1 (1)
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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media
Lily mitosis 13
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A light microscope image of cells from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media
Mouse cerebellum
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The cerebellum is the brain's locomotion control center. Found at the base of your brain, the cerebellum is a single layer of tissue with deep folds like an accordion. National Center for Microscopy and Imaging Research (NCMIR) View Media
Structure of amyloid-forming prion protein
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This structure from an amyloid-forming prion protein shows one way beta sheets can stack. Douglas Fowler, University of Washington View Media
Normal vascular development in frog embryos
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In vivo vascular development in kdr:GFP frogs. Related to images 3403 and 3405. Hye Ji Cha, University of Texas at Austin View Media
Network diagram of genes, cellular components and processes (labeled)
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This image shows the hierarchical ontology of genes, cellular components and processes derived from large genomic datasets. From Dutkowski et al. Janusz Dutkowski and Trey Ideker, University of California, San Diego View Media
Fungal lipase (2)
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Crystals of fungal lipase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Hydra 03
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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View Media
Himastatin
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A model of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media
Fluorescent C. elegans showing muscle and ribosomal protein
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C. elegans, a tiny roundworm, with a ribosomal protein glowing red and muscle fibers glowing green. Researchers used these worms to study a molecular pathway that affects aging. Jarod Rollins, Mount Desert Island Biological Laboratory. View Media
Dengue virus membrane protein structure
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Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View Media
Magnetic Janus particle activating a T cell
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A Janus particle being used to activate a T cell, a type of immune cell. Yan Yu, Indiana University, Bloomington. View Media
Three muscle fibers; the middle has a defect found in some neuromuscular diseases
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Of the three muscle fibers shown here, the one on the right and the one on the left are normal. The middle fiber is deficient a large protein called nebulin (blue). Christopher Pappas and Carol Gregorio, University of Arizona View Media
Central dogma, illustrated (with labels and numbers for stages)
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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View Media
DNase
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Crystals of DNase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Chromatin in human fibroblast
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The nucleus of a human fibroblast cell with chromatin—a substance made up of DNA and proteins—shown in various colors. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media
Adult Hawaiian bobtail squid burying in the sand
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Each morning, the nocturnal Hawaiian bobtail squid, Euprymna scolopes, hides from predators by digging into the sand. At dusk, it leaves the sand again to hunt. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
