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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Honeybee brain
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Insect brains, like the honeybee brain shown here, are very different in shape from human brains. Gene Robinson, University of Illinois at Urbana-Champaign. View MediaGenetically identical mycobacteria respond differently to antibiotic 2
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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View MediaBacterial symbionts colonizing the crypts of a juvenile Hawaiian bobtail squid light organ
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A light organ (~0.5 mm across) of a Hawaiian bobtail squid, Euprymna scolopes, stained blue. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaCrane fly spermatocyte undergoing meiosis
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A crane fly spermatocyte during metaphase of meiosis-I, a step in the production of sperm. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaBrain waves of a patient anesthetized with propofol
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A representation of a patient’s brain waves after receiving the anesthetic propofol. Emery N. Brown, M.D., Ph.D., Massachusetts General Hospital/Harvard Medical School, Picower Institute for Learning and Memory, and Massachusetts Institute of Technology. View MediaHIV Capsid
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This image is a computer-generated model of the approximately 4.2 million atoms of the HIV capsid, the shell that contains the virus' genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View MediaCas9 protein involved in the CRISPR gene-editing technology
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In the gene-editing tool CRISPR, a small strand of RNA identifies a specific chunk of DNA. Janet Iwasa View MediaNeurons from human ES cells
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These neural precursor cells were derived from human embryonic stem cells. The neural cell bodies are stained red, and the nuclei are blue. Xianmin Zeng lab, Buck Institute for Age Research, via CIRM View MediaCircadian rhythms and the SCN
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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. NIGMS View MediaSea urchin embryo 04
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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View MediaDNase
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Crystals of DNase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaMultivesicular bodies containing intralumenal vesicles assemble at the vacuole 1
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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View MediaProteins related to myotonic dystrophy
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Myotonic dystrophy is thought to be caused by the binding of a protein called Mbnl1 to abnormal RNA repeats. Manuel Ares, University of California, Santa Cruz View MediaModeling disease spread
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What looks like a Native American dream catcher is really a network of social interactions within a community. Stephen Eubank, University of Virginia Biocomplexity Institute (formerly Virginia Bioinformatics Institute) View MediaRNase A (2)
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A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaHydra 06
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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View MediaMapping human genetic variation
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This map paints a colorful portrait of human genetic variation around the world. Noah Rosenberg and Martin Soave, University of Michigan View MediaCentromeres on human chromosomes
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Human metaphase chromosomes are visible with fluorescence in vitro hybridization (FISH). Centromeric alpha satellite DNA (green) are found in the heterochromatin at each centromere. Peter Warburton, Mount Sinai School of Medicine View MediaSpreading Cells 01
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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View MediaDolly the sheep
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Scientists in Scotland were the first to clone an animal, this sheep named Dolly. She later gave birth to Bonnie, the lamb next to her. View MediaCascade reaction promoted by water
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This illustration of an epoxide-opening cascade promoted by water emulates the proposed biosynthesis of some of the Red Tide toxins. Tim Jamison, Massachusetts Institute of Technology View MediaProtein clumping in zinc-deficient yeast cells
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The green spots in this image are clumps of protein inside yeast cells that are deficient in both zinc and a protein called Tsa1 that prevents clumping. Colin MacDiarmid and David Eide, University of Wisconsin--Madison View MediaMolecular interactions at the astrocyte nuclear membrane
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These ripples of color represent the outer membrane of the nucleus inside an astrocyte, a star-shaped cell inside the brain. Katerina Akassoglou, Gladstone Institute for Neurological Disease & UCSF View MediaLysosomes and microtubules
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Lysosomes (yellow) and detyrosinated microtubules (light blue). Lysosomes are bubblelike organelles that take in molecules and use enzymes to break them down. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaScientists display X-ray diffraction pattern obtained with split X-ray beamline
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Scientists from Argonne National Laboratory's Advanced Photon Source (APS) display the first X-ray diffraction pattern obtained from a protein crystal using a split X-ray beam, the first of its kind a GM/CA Collaborative Access Team View MediaBeta-galactosidase montage showing cryo-EM improvement--transparent background
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Composite image of beta-galactosidase showing how cryo-EM’s resolution has improved dramatically in recent years. Older images to the left, more recent to the right. Veronica Falconieri, Sriram Subramaniam Lab, National Cancer Institute View MediaHeLa cells
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Multiphoton fluorescence image of HeLa cells stained with the actin binding toxin phalloidin (red), microtubules (cyan) and cell nuclei (blue). Nikon RTS2000MP custom laser scanning microscope. National Center for Microscopy and Imaging Research (NCMIR) View MediaMap of protein structures 01
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A global "map of the protein structure universe." The Berkeley Structural Genomics Center has developed a method to visualize the vast universe of protein structures in which proteins of similar struc Berkeley Structural Genomics Center, PSI View MediaPrion protein fibrils 1
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Recombinant proteins such as the prion protein shown here are often used to model how proteins misfold and sometimes polymerize in neurodegenerative disorders. This prion protein was expressed in E. Ken Pekoc (public affairs officer) and Julie Marquardt, NIAID/ Rocky Mountain Laboratories View MediaTracking cells in a gastrulating zebrafish embryo
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During development, a zebrafish embryo is transformed from a ball of cells into a recognizable body plan by sweeping convergence and extension cell movements. This process is called gastrulation. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View MediaXenopus laevis egg
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Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View MediaiPS cell facility at the Coriell Institute for Medical Research
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This lab space was designed for work on the induced pluripotent stem (iPS) cell collection, part of the NIGMS Human Genetic Cell Repository at the Coriell Institute for Medical Research. Courtney Sill, Coriell Institute for Medical Research View MediaRepairing DNA
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Like a watch wrapped around a wrist, a special enzyme encircles the double helix to repair a broken strand of DNA. Tom Ellenberger, Washington University School of Medicine View MediaSeeing signaling protein activation in cells 01
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Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins, regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View MediaBovine trypsin
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A crystal of bovine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaNatcher Building 09
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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View MediaNatcher Building 02
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NIGMS staff are located in the Natcher Building on the NIH campus. Alisa Machalek, National Institute of General Medical Sciences View MediaAxolotl showing nervous system
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The head of an axolotl—a type of salamander—that has been genetically modified so that its developing nervous system glows purple and its Schwann cell nuclei appear light blue. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View MediaLife of an AIDS virus (with labels and stages)
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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View MediaCellular polarity
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As an egg cell develops, a process called polarization controls what parts ultimately become the embryo's head and tail. This picture shows an egg of the fruit fly Drosophila. Wu-Min Deng, Florida State University View MediaPetri dish containing C. elegans
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This Petri dish contains microscopic roundworms called Caenorhabditis elegans. Researchers used these particular worms to study how C. H. Robert Horvitz and Dipon Ghosh, Massachusetts Institute of Technology. View Media3D image of actin in a cell
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Actin is an essential protein in a cell's skeleton (cytoskeleton). It forms a dense network of thin filaments in the cell. Xiaowei Zhuang, Howard Hughes Medical Institute, Harvard University View MediaBacillus anthracis being killed
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Bacillus anthracis (anthrax) cells being killed by a fluorescent trans-translation inhibitor, which disrupts bacterial protein synthesis. Kenneth Keiler, Penn State University View MediaNerve ending
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A scanning electron microscope picture of a nerve ending. It has been broken open to reveal vesicles (orange and blue) containing chemicals used to pass messages in the nervous system. Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaFruit fly ovarioles
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Three fruit fly (Drosophila melanogaster) ovarioles (yellow, blue, and magenta) with egg cells visible inside them. Ovarioles are tubes in the reproductive systems of female insects. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View MediaFruit fly ovaries
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Fruit fly (Drosophila melanogaster) ovaries with DNA shown in magenta and actin filaments shown in light blue. This image was captured using a confocal laser scanning microscope.Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media
Protein purification robot in action 01
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A robot is transferring 96 purification columns to a vacuum manifold for subsequent purification procedures. The Northeast Collaboratory for Structural Genomics View MediaPlastic-eating enzymes
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PETase enzyme degrades polyester plastic (polyethylene terephthalate, or PET) into monohydroxyethyl terephthalate (MHET). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media