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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Circadian rhythm neurons in the fruit fly brain
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Some nerve cells (neurons) in the brain keep track of the daily cycle. This time-keeping mechanism, called the circadian clock, is found in all animals including us. Justin Blau, New York University View MediaIsolated Planarian Pharynx
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The feeding tube, or pharynx, of a planarian worm with cilia shown in red and muscle fibers shown in green View MediaMagnetic Janus particle activating a T cell
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A Janus particle being used to activate a T cell, a type of immune cell. Yan Yu, Indiana University, Bloomington. View MediaDense tubular matrices in the peripheral endoplasmic reticulum (ER) 2
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Three-dimensional reconstruction of a tubular matrix in a thin section of the peripheral endoplasmic reticulum between the plasma membranes of the cell. Jennifer Lippincott-Schwartz, Howard Hughes Medical Institute Janelia Research Campus, Virginia View MediaRed blood cells
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This image of human red blood cells was obtained with the help of a scanning electron microscope, an instrument that uses a finely focused electron beam to yield detailed images of the surface of a sa Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaAnti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 01
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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View MediaAnthrax bacteria (green) being swallowed by an immune system cell
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Multiple anthrax bacteria (green) being enveloped by an immune system cell (purple). Anthrax bacteria live in soil and form dormant spores that can survive for decades. Camenzind G. Robinson, Sarah Guilman, and Arthur Friedlander, United States Army Medical Research Institute of Infectious Diseases View MediaCorrelative imaging by annotation with single molecules (CIASM) process
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These images illustrate a technique combining cryo-electron tomography and super-resolution fluorescence microscopy called correlative imaging by annotation with single molecules (CIASM). Peter Dahlberg, Stanford University. View MediaLysosomes
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Lysosomes have powerful enzymes and acids to digest and recycle cell materials. Judith Stoffer View MediaUbiquitin-fold modifier 1 from C. elegans
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Solution NMR structure of protein target WR41 (left) from C. elegans. Northeast Structural Genomics Consortium View MediaBence Jones protein MLE
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A crystal of Bence Jones protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaHuman ES cells turn into insulin-producing cells
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Human embryonic stem cells were differentiated into cells like those found in the pancreas (blue), which give rise to insulin-producing cells (red). Eugene Brandon, ViaCyte, via CIRM View MediaLily mitosis 11
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A light microscope image of cells from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaCalcium uptake during ATP production in mitochondria
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Living primary mouse embryonic fibroblasts. Mitochondria (green) stained with the mitochondrial membrane potential indicator, rhodamine 123. Nuclei (blue) are stained with DAPI. Lili Guo, Perelman School of Medicine, University of Pennsylvania View MediaSTORM image of axonal cytoskeleton
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This image shows the long, branched structures (axons) of nerve cells. Xiaowei Zhuang Laboratory, Howard Hughes Medical Institute, Harvard University View MediaColorful communication
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The marine bacterium Vibrio harveyi glows when near its kind. Bonnie Bassler, Princeton University View MediaCulex quinquefasciatus mosquito larva
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A mosquito larva with genes edited by CRISPR. The red-orange glow is a fluorescent protein used to track the edits. Valentino Gantz, University of California, San Diego. View MediaBacterial spore
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A spore from the bacterium Bacillus subtilis shows four outer layers that protect the cell from harsh environmental conditions. Patrick Eichenberger, New York University View MediaCarbon building blocks (with examples)
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The arrangement of identical molecular components can make a dramatic difference. For example, carbon atoms can be arranged into dull graphite (left) or sparkly diamonds (right). Crabtree + Company View MediaZebrafish pigment cell
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Pigment cells are cells that give skin its color. David Parichy, University of Washington View MediaATP synthase
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The world's smallest motor, ATP synthase, generates energy for the cell. See image 2518 for a labeled version of this illustration. Crabtree + Company View MediaChromatin in human fibroblast
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The nucleus of a human fibroblast cell with chromatin—a substance made up of DNA and proteins—shown in various colors. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaRecombinant DNA (with labels)
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To splice a human gene (in this case, the one for insulin) into a plasmid, scientists take the plasmid out of an E. Crabtree + Company View MediaDrosophila
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Two adult fruit flies (Drosophila) Dr. Vicki Losick, MDI Biological Laboratory, www.mdibl.org View MediaFruit fly sperm cells
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Developing fruit fly spermatids require caspase activity (green) for the elimination of unwanted organelles and cytoplasm via apoptosis. Hermann Steller, Rockefeller University View MediaDynamic cryo-EM model of the human transcription preinitiation complex
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Gene transcription is a process by which information encoded in DNA is transcribed into RNA. Eva Nogales, Berkeley Lab View MediaFruit fly ovary_2
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A fruit fly ovary, shown here, contains as many as 20 eggs. Fruit flies are not merely tiny insects that buzz around overripe fruit--they are a venerable scientific tool. Denise Montell, University of California, Santa Barbara View MediaCentral dogma, illustrated (with labels and numbers for stages)
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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View MediaRNA folding in action
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An RNA molecule dynamically refolds itself as it is being synthesized. When the RNA is short, it ties itself into a “knot” (dark purple). Julius Lucks, Northwestern University View MediaRNA polymerase
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RNA polymerase (purple) is a complex enzyme at the heart of transcription. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaLily mitosis 13
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A light microscope image of cells from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaArabidopsis leaf injected with a pathogen
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This is a magnified view of an Arabidopsis thaliana leaf eight days after being infected with the pathogen Hyaloperonospora arabidopsidis, which is closely related to crop pathogens that Jeff Dangl, University of North Carolina, Chapel Hill View MediaMultivesicular bodies containing intralumenal vesicles assemble at the vacuole 1
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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View MediaFruit fly nurse cells during egg development
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In many animals, the egg cell develops alongside sister cells. Adam C. Martin, Massachusetts Institute of Technology. View MediaBeaded bacteriophage
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This sculpture made of purple and clear glass beads depicts bacteriophage Phi174, a virus that infects bacteria. It rests on a surface that portrays an adaptive landscape, a conceptual visualization. Holly Wichman, University of Idaho. (Surface by A. Johnston; photo by J. Palmersheim) View MediaCell-like compartments emerging from scrambled frog eggs
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Cell-like compartments spontaneously emerge from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View MediaAnti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 04
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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View MediaSleep and the fly brain
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In the top snapshots, the brain of a sleep-deprived fruit fly glows orange, marking high concentrations of a synaptic protein called Bruchpilot (BRP) involved in communication between neurons. Chiara Cirelli, University of Wisconsin-Madison View MediaTelomerase illustration
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Reactivating telomerase in our cells does not appear to be a good way to extend the human lifespan. Cancer cells reactivate telomerase. Judith Stoffer View MediaYeast cells with endocytic actin patches
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Yeast cells with endocytic actin patches (green). These patches help cells take in outside material. When a cell is in interphase, patches concentrate at its ends. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View MediaCircadian rhythm
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The human body keeps time with a master clock called the suprachiasmatic nucleus or SCN. Crabtree + Company View MediaStructure of heme, top view
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Molecular model of the struture of heme. Heme is a small, flat molecule with an iron ion (dark red) at its center. Rachel Kramer Green, RCSB Protein Data Bank View MediaMosaicism in C. elegans (White Background)
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In the worm C. elegans, double-stranded RNA made in neurons can silence matching genes in a variety of cell types through the transport of RNA between cells. Snusha Ravikumar, Ph.D., University of Maryland, College Park, and Antony M. Jose, Ph.D., University of Maryland, College Park View MediaHuman ES cells differentiating into neurons
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This image shows hundreds of human embryonic stem cells in various stages of differentiating into neurons. Guoping Fan lab, University of California, Los Angeles, via CIRM View MediaHeLa cells
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Multiphoton fluorescence image of HeLa cells stained with the actin binding toxin phalloidin (red), microtubules (cyan) and cell nuclei (blue). Nikon RTS2000MP custom laser scanning microscope. National Center for Microscopy and Imaging Research (NCMIR) View MediaTrigonium diatom
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A Trigonium diatom imaged by a quantitative orientation-independent differential interference contrast (OI-DIC) microscope. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaEarly ribbon drawing of a protein
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This ribbon drawing of a protein hand drawn and colored by researcher Jane Richardson in 1981 helped originate the ribbon representation of proteins that is now ubiquitous in molecular graphics. Jane Richardson, Duke University Medical Center View MediaSea urchin embryo 06
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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View MediaMitochondria and endoplasmic reticulum
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A computer model shows how the endoplasmic reticulum is close to and almost wraps around mitochondria in the cell. The endoplasmic reticulum is lime green and the mitochondria are yellow. Bridget Wilson, University of New Mexico View MediaCRISPR Illustration Frame 3
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media