Continuing our longstanding commitment to train the next generation of biomedical scientists and support the careers of students and postdoctoral scientists from diverse backgrounds, for example groups underrepresented in biomedical research, we sought input from the community through a request for information (RFI) on strategies to enhance successful postdoctoral career transitions to promote faculty diversity, specifically in research-intensive institutions. The RFI was open May 24 to July 20, 2018, and received a total of 89 unique responses from stakeholders including postdoctoral scientists, faculty members, and professional societies.

Are you applying for the NIGMS Predoctoral Institutional Research Training Grant (T32) - PAR-17-341? If so, it's important you note revisions to our FOA instructions that clarify application requirements. We have also added a new requirement concerning institutional responsibilities related to harassment. We encourage you to read the full NIH Guide notice, published on August 23, 2018. Key points include:

UPDATE: The Maximizing Access to Research Careers (MARC), Undergraduate Research Training Initiative for Student Enhancement (U-RISE), Initiative for Maximizing Student Development (IMSD), Graduate Research Training Initiative for Student Enhancement (G-RISE), Bridges to the Baccalaureate, and Bridges to the Doctorate funding opportunity announcements are now available. NIGMS has a longstanding commitment to developing a diverse pool of biomedical scientists through a variety of institutional training and student development programs. Based on stakeholders’ feedback through Requests for Information (NOT-GM-15-108; NOT-GM-17-017), as well as extensive analyses and discussions with NIH staff and the community, we intend to make adjustments to our programs designed to enhance the diversity in the biomedical research workforce. The modifications, which the NIGMS Council recently approved, are designed to: 1) provide equity of trainee support across programs; 2) prevent programmatic overlap; 3) align the funding strategies with the programmatic goals; 4) tailor expectation of outcomes, support mechanisms, and review considerations according to the institution’s level of research activity; and 5) strengthen our ability to evaluate the success of the programs. The changes, described in more detail in the recent Videocast of the Council Open Session, will impact the Initiative for Maximizing Student Development (IMSD), the Research Initiative for Scientific Enhancement (RISE) program, and the Maximizing Access to Research Careers - Undergraduate Student Training in Academic Research (MARC U-STAR) programs. We don’t anticipate any immediate changes to our Postbaccalaureate Research Education Program (PREP). Possible adjustments to the Bridges to the Baccalaureate and Bridges to the Doctorate programs are currently under discussion.

NIGMS has a longstanding commitment to train the next generation of biomedical scientists and support the training of students from diverse backgrounds, including groups underrepresented in biomedical research, through fellowships, career development grants, and institutional training and student development programs. These programs, and other efforts, have contributed to a substantial increase in the talent pool of well-trained biomedical Ph.D.s from historically underrepresented racial and ethnic groups. However, increasing evidence shows that transitions of these talented scientists from postdoctoral training into independent faculty positions at research-intensive institutions is a key point at which they exit the NIH-funded research workforce. Similarly, women have earned a majority of biomedical Ph.D.s since 2008 but approximately one-third of NIH-funded principal investigators are women.

We have undertaken a number of efforts to facilitate the career transitions of postdoctoral scientists from diverse groups into the professoriate including Institutional Research and Academic Career Development Awards and research supplements to promote diversity in health-related research and re-entry into biomedical research careers. Additionally, we administer the NIH Common Fund’s National Research Mentoring Network, a nationwide consortium of biomedical professionals and institutions collaborating to provide biomedical trainees from all backgrounds and at all levels with evidence-based mentorship and professional development programs. While these efforts have supported the development of highly-trained biomedical scientists who have the necessary knowledge and skills to pursue independent biomedical research careers, we need additional strategies to promote transitions to independent faculty positions at research-intensive institutions.

To continue our efforts to catalyze the modernization of biomedical graduate education, we invite eligible NIGMS-funded T32 predoctoral training programs to submit administrative supplement requests to develop new curricular and training activities to enhance the program’s ability to: 1) provide graduate trainees with a strong foundation in research design and methods in areas related to conducting rigorous and transparent research to enhance reproducibility (PA-18-756); 2) prepare students for diverse careers in the biomedical research workforce (PA-18-757); 3) develop the knowledge and skills of trainees to enhance laboratory safety (PA-18-758); and 4) develop the technical, operational, and professional skills of predoctoral biomedical researchers (PA-18-759). Grantees should consider the following before applying:

We are pleased to announce that NIH Leadership has granted clearance for the second, final phase of the Diversity Program Consortium (DPC), a national program that is part of a larger, trans-NIH effort to enhance diversity in the biomedical research workforce. To accomplish this goal, the DPC takes a scientific approach to evaluating training and mentoring interventions. Two components of the second phase will be open competitions: the National Research Mentoring Network (NRMN) and the DPC Dissemination and Translation Awards (DPC-DaTA). The DPC-DaTA grants will allow sites that are not currently part of the DPC to implement sustainable training, mentoring, or research-capacity building interventions using DPC evaluation methods. NIH intends to release the DPC-DaTA FOAs in 2019.

The NRMN funding opportunity announcements (FOAs) were released on February 16, 2018. They include:

• The Science of Mentoring and Networking (U01) (RFA-RM-18-004). Applicants may submit proposals for research projects in the following areas: 1) The Science of Mentorship, 2) Professional Networking, or 3) Navigating Critical Career Transition Points. Using randomized control trial approaches, case controls, matched pair designs, or other rigorous designs, applicants will explore their research questions and contribute to building the knowledge base to inform the scientific community about their thematic area.
• NRMN Coordination Center (U24) (RFA-RM-18-003). One service award will be granted to develop an NRMN Coordinating Center. This Center will build upon and improve the current NRMN Administrative Core and work in conjunction with the Center for Evaluation and Coordination (CEC). It will coordinate trans-NRMN activities, and provide infrastructure and expertise surrounding data collection, storage, de-identification, and reporting.
• NRMN Resource Center (U24) (RFA-RM-18-002). One service award will be granted for an NRMN Resource Center. This center will be analogous to the current U54 Mentorship and Networking Core and will provide a web-based mentoring tool to facilitate real-time mentor/mentee engagement. It will also oversee management of the NRMN website and serve as a platform for publicly available mentoring resources and tools.

Two components of the DPC for the second phase will be limited competitions. The Building Infrastructure Leading to Diversity (BUILD) (U54) (NOT-RM-18-005) will allow meritorious sites to complete their BUILD experiments. Review will include a focus on site-specific and consortium-wide experiments, and emphasize sustainability and dissemination. The Center for Evaluation and Coordination (CEC) (U54) (NOT-RM-18-006) will allow for uninterrupted data collection. The review will focus on the current center’s strengths and weaknesses, allowing for improvements and course corrections. Sustainability and dissemination will be emphasized.

Contact for questions? Mercedes Rubio for NRMN inquiries, Anissa Brown for BUILD inquiries, Michael Sesma for CEC inquiries, and Alison Gammie for DPC-DaTA inquiries.

We’ve just released a new training funding opportunity announcement (FOA) specifically tailored for predoctoral graduate programs in the basic biomedical sciences. Through this FOA, we intend to encourage changes in biomedical graduate training that allow it to keep pace with the rapid evolution of the research enterprise, which is increasingly complex, quantitative, interdisciplinary, and collaborative.

The overarching objective of this new predoctoral T32 training program is to develop a diverse pool of well-trained scientists who have the following:

• A broad understanding across biomedical disciplines, and the skills to independently acquire the knowledge needed to advance their chosen field.
• The ability to think critically, independently, and to identify important biomedical research questions and approaches that push forward the boundaries of their areas of study.
• A strong foundation in scientific reasoning, rigorous research design, experimental methods, quantitative and computational approaches, as well as data analysis and interpretation.
• A commitment to approaching and conducting biomedical research responsibly and with integrity.
• Experience initiating, conducting, interpreting, and presenting rigorous and reproducible biomedical research with increasing self-direction.
• The ability to work effectively in teams with colleagues from a variety of cultural and scientific backgrounds, and to promote inclusive and supportive scientific research environments.
• The skills to teach and communicate scientific research methodologies and findings to a wide variety of audiences (e.g., discipline-specific, across disciplines, and the public).
• The knowledge, professional skills, and experiences required to identify and transition into careers in the biomedical research workforce (i.e., the breadth of careers that sustain biomedical research in areas that are relevant to the NIH mission).

Because diversity at all levels is integral to research and training excellence, this FOA is also intended to fund outstanding research training environments that support trainees from all backgrounds, and to enhance diversity in the biomedical enterprise by paying particular attention to the inclusion of individuals from groups underrepresented in the biomedical sciences.

The goal is of this FOA is to enable the community to develop and implement innovative approaches to training and mentoring that will effectively and efficiently train future generations of outstanding biomedical scientists. This funding announcement is designed to allow biomedical graduate education to preserve the best elements of the current system, while enhancing the focus on the trainee development of the technical, operational, and professional skills needed to transition into successful and productive careers in the biomedical research workforce.

The new FOA will apply to all NIGMS predoctoral T32 training grants submitted for receipt dates beginning May 25, 2018, except the Medical Scientist Training Program, which will remain on the parent T32 announcement for now. Because this is a new funding announcement, all applications (including those from previously established programs) must be submitted as new (-01), however applicants may describe up to 15 years of outcomes in the narrative.

As always, we welcome your feedback. You can email your questions and comments or post them here.

UPDATE: The new predoctoral T32 funding opportunity announcement specifically tailored for predoctoral graduate programs in the basic biomedical sciences is now available. At the recent NIGMS Advisory Council meeting, the Division of Training, Workforce Development, and Diversity requested, and received, approval to write a new predoctoral T32 funding opportunity announcement (FOA), specifically tailored for predoctoral graduate programs in the basic sciences and designed to help catalyze the modernization of biomedical graduate education. The goal is to enable the community to develop and implement innovative approaches to education and mentoring that will more effectively and efficiently train future generations of outstanding biomedical researchers, and will allow graduate education to keep pace with the rapid evolution of the biomedical research enterprise. Taking into account the feedback we have received from various stakeholders over the past year, the new FOA will:

• Emphasize the development of a diverse pool of exceptionally well-trained scientists;
• Focus on skills development, rigor and reproducibility, inclusive and supportive training environments, and responsible conduct;
• Address conflicts in the incentive structure of the research enterprise that adversely impact biomedical graduate education;
• Encourage the use and dissemination of evidence-based, innovative educational and mentoring practices;
• Emphasize improvements in career preparation (broadly defined), and dissemination of career outcomes on publicly available sites.

The intention is not to layer additional activities onto existing structures. Instead, this funding announcement is designed to allow for a creative reinvention of biomedical graduate education that preserves the best elements, while enhancing the focus on the development of research and professional skills by trainees. We expect to issue the new T32 FOA this fall and to receive the first applications in May 2018. The new FOA will apply to all NIGMS predoctoral T32 training grants, except for the Medical Scientist Training Program (MSTP), which will remain on the parent T32 announcement for now. We plan in the future to develop a parallel FOA that is specific for the goals of the MSTP. We encourage the community to watch the presentation at our Council meeting and view the slide deck. As always, we welcome your input and feedback on these plans. You can post your comments below.

After attending the Diversity Program Consortium (DPC) annual meeting in mid-October and learning about the progress the consortium has made and its future plans, we’re feeling energized as we begin the third year of this grant. The DPC, supported by the NIH Common Fund and managed by NIGMS, is a cooperative agreement focused on finding the best ways to improve research training and mentoring in the biomedical sciences and on engaging a more diverse field of individuals in biomedical research careers. The consortium includes three interconnected programs: Building Infrastructure Leading to Diversity (BUILD), the National Research Mentoring Network (NRMN) and the Coordination and Evaluation Center (CEC). The annual meeting brought together over 100 representatives from NIH and each grantee site to discuss DPC achievements, challenges and opportunities. The agenda, organized by the CEC, included two full days of presentations and breakout sessions.

NIGMS actively supports efforts to catalyze the modernization of biomedical graduate education. We have undertaken a number of initiatives to stimulate this process, including hosting a symposium to showcase innovations in biomedical graduate education and providing administrative supplements to T32 predoctoral training grants to enhance rigor and reproducibility, career development and skills development. On June 8, 2016, we took another step to encourage such change with the release of a Request for Information (RFI) seeking input on how our institutional predoctoral training grants program can be used to promote innovations in training. The RFI asked members of the community to weigh in on the strengths and weaknesses of the current system, the skills the next generation of graduate students should acquire, barriers to change and strategies to promote change through our institutional predoctoral research training grants. We received 90 unique responses from stakeholders ranging from students and faculty to institutions and professional societies. Themes represented in the responses were organized around five major categories:

• Institutional and training-related issues,
• Skills development,
• Systemic issues within the research enterprise,
• Careers, and
• Administrative and review issues.

While NIGMS recognizes that those who responded to the RFI are unlikely to represent a random subset of the individuals and organizations who have a stake in graduate biomedical education, these responses provide insights regarding how members of the extramural community view the current challenges and opportunities in graduate biomedical education. As such, these comments will inform NIGMS’ ongoing efforts to catalyze the modernization of graduate education through a new predoctoral T32 funding announcement, which is currently under development. For more details about the analysis, we encourage you to explore the report.