NIGMS-Sponsored Training Program Maps
Answers to Institutional Predoctoral Training Grants (T32) Frequently Asked Questions
NIH Predoctoral Stipends, Training Related Expenses, Institutional Allowance, and Tuition/Fees Policy on NRSA Awards
Items Considered by Reviewers in Evaluating Institutional Training Grant Applications
Responsible Conduct of Research
NIGMS accepts predoctoral training grant applications to enhance graduate (Ph.D.) research training in 12 broad areas
of basic biomedical sciences. The proposed training program should be broadly-based and foundational in nature.
Applicants are expected to identify the program area that they are applying to under the Agency Routing
Identifier Field on the Cover Page of their application (see NOT-GM-19-012 for
details). In addition to training in these 12 broad areas, NIGMS supports the integrated
medical and graduate research training through the Medical Scientist Training Program (MSTP). For general
information about these institutional NRSA T32 predoctoral training programs, contact Dr. Shiva Singh.
Basic Biomedical Sciences (PAR-17-341; see also Guide Notice
Integrated Medical and Graduate Training (PA-19-036)
Behavioral-Biomedical Sciences Interface: Dr.
Programs in this area should provide graduate research training for students at the behavioral sciences-biomedical
sciences interface. The goal of the program is to develop basic behavioral scientists with rigorous broad-based
training in biology and biomedical science who are available to assume leadership roles related to the nation's
biomedical research needs. Programs must provide an interdisciplinary research training experience and curriculum
for predoctoral trainees that integrates both behavioral and biomedical perspectives, approaches and methodologies.
Training programs must include coursework, laboratory rotations and programmatic activities that reinforce training
at this interface. Significant participation by faculty and leadership from both behavioral and biomedical science
departments is required, as is co-mentoring of trainees by faculty from both components.
Biostatistics: Dr. Kenneth Gibbs
Programs in this area should provide training that integrates biostatistical theory and evolving methodologies with
basic biomedical research including, but not limited to, bioinformatics, genetics, molecular biology, cellular
processes and physiology, as well as epidemiological, clinical and behavioral studies. The goal is to ensure that a
workforce of biostatisticians with a deep understanding of statistical theory and new methodologies is available to
assume leadership roles related to the nation's biomedical research needs.
Biotechnology: Dr. Patrick Brown
Programs in this area should train students in the techniques and principles needed to pursue research in
biotechnology. The education should be multidisciplinary, but provide a firm grounding in one or more of the fields
that contribute to biotechnology, such as engineering, biophysics, biochemistry, genetics and cell biology. Faculty
and students participating in this program should be drawn from several departments, but should have a focus on
engineering. The faculty should be conducting research relevant to the understanding and utilization of biological
processes for biotechnological applications. In addition to scientific, theoretical and practical knowledge,
programs are expected to provide training in communications skills, career development and an understanding of
regulatory, commercialization and IP issues in bringing a biotechnology product to the market. The program requires
a mandatory two-to-three month internship in pharmaceutical or biotechnological industry. A close interaction
between academic and industrial partners is strongly recommended.
Cellular, Biochemical, and Molecular Sciences: Dr. Desirée Salazar and Dr.
Programs in this area should be cross-disciplinary and involve in-depth study of biological problems at the level of
the cellular and molecular sciences. The research training offered should encompass related disciplines, such as
biochemistry, bioinformatics, biophysics, chemistry, cell biology, developmental biology, genetics, immunology,
microbiology, molecular biology, neurobiology and pathology. These research opportunities should be available in the
represented disciplines with faculty mentors from interacting departments and/or interdisciplinary Ph.D. programs.
Chemistry-Biology Interface (CBI): Dr. Miles
Programs in this area should provide significant biological training to students receiving in-depth training in
synthetic/mechanistic chemistry and provide significant training in synthetic/mechanistic chemistry to students
being trained in depth in the biological sciences. It is expected that CBI programs will consist of faculty drawn
from departments of chemistry, medicinal chemistry and/or pharmaceutical chemistry and faculty from the biological
disciplines, such as genetics, cellular, biochemical and molecular sciences. Students trained at the
chemistry-biology interface should be well-grounded in a core discipline and sufficiently well-trained in
complementary fields to allow them to work effectively in a multidisciplinary team.
Computational Biology, Bioinformatics, and Biomedical Data Science: Dr. Veerasamy "Ravi" Ravichandran and Dr. Haluk Resat
Programs should train students in the fundamentals and applications of computational and information sciences to
gain insights and develop new strategies to solve problems relevant to basic biomedical research. Of particular
interest are multi-disciplinary programs providing the skills to address biomedical research questions by utilizing
large data sets and multiscale approaches. Accordingly, multi-department applications which partner biological
sciences with quantitative and computational sciences (e.g., data science, computer science, statistics,
mathematics, informatics, engineering) are encouraged. Training should include the use of theory, simulations, data
sciences, machine learning, artificial intelligence, and other bioinformatics and computational approaches to
address the full spectrum of basic research areas in the biomedical sciences, including for example, the
fundamentals of analysis and interpretation of molecular sequence and structure, molecular function, cellular
function, physiology, genomics, and genetics. In accordance with the NIH
Strategic Plan for Data Science, training should also include aspects of fair and ethical data use, data
sharing, and data security and confidentiality. NIGMS encourages programs to make use of resources and expertise
available in the private sector to develop student skills and career paths in areas including efficient computer
code development and use of emerging technologies and platforms.
Genetics: Dr. Michael Bender
Programs in this area should emphasize broad, multidisciplinary training in the principles and mechanisms of
genetics and related sciences. Training in a variety of areas such as classical genetics, molecular genetics,
population and behavioral genetics and developmental genetics should be offered. Programs may also include training
and research opportunities in related disciplines such as biochemistry, cell biology and statistics. Programs are
generally expected to include faculty members in disciplines other than genetics.
Molecular Biophysics: Dr. Paula
Programs in this area should provide multidisciplinary training that focuses on the application of the concepts and
methods of the physical sciences to explain biological function in terms of molecular structure, dynamics, and
organization from single molecules to supramolecular structures. These programs should bring together faculty and
students from departments such as chemistry, physics, and engineering who have an interest in quantitative,
biologically-related research with faculty and students in biological science departments whose orientation is
mechanistic and structural biology.
Molecular Medicine: Dr. Alison Cole
Programs in this area should provide training that combines rigorous didactic training in the basic biomedical
sciences with exposure to concepts and knowledge underlying the molecular basis of disease. The goal is to train a
cadre of scientists prepared to work at the interface of basic biomedical science and clinical research, an area
sometimes referred to as translational research. Trainees should have dual mentors in basic and clinical science,
and exposure to the concepts of medicine. Training faculty should be broadly drawn from multiple departments and
disciplines and thesis research topics should reflect a broad range of interdisciplinary opportunities in the basic
biomedical sciences. This training opportunity should be primarily designed for Ph.D. candidates.
Pharmacological Sciences: Dr. Sailaja
Programs in this area should incorporate a quantitative and systems approach to pharmacology. Individuals should
receive training that will enable them to conduct research in the development of therapeutic agents. It should also
provide training in regulatory sciences that includes the study of pharmacometrics and the principles of absorption,
distribution, metabolism, excretion and toxicology (ADME-Tox). Thesis research opportunities should be available
with faculty members in a variety of disciplines, such as biochemistry, physiology, molecular biology, cell biology,
chemistry, medicinal chemistry and toxicology, as well as pharmacology. Students trained in this program should be
able to contribute to the design and evaluation of therapeutic agents and strategies based upon the competence they
have acquired through specialized training in the pharmacological sciences, both through their individualized
research area and their understanding and being conversant with the overall drug discovery and development process.
Systems and Integrative Biology: Dr. Zhongzhen
Programs in this area should provide training directed toward building the broad research competence required to
investigate the integrative, regulatory and developmental processes of higher organisms and the functional
components of these processes. The training program should bring together varied resources, approaches and thesis
research opportunities with faculty mentors of such disciplines/departments as physiology, biomedical engineering,
the behavioral sciences, biochemistry, systems biology and cell and developmental biology. Graduates of the program
should be well versed in quantitative approaches to biology.
Transdisciplinary Basic Biomedical Sciences: Dr. Luis
Programs in this area should support training in two or more of the T32 areas listed above, or may include other
emerging area(s) within the
Training in the transdisciplinary area is designed to increase efficiencies and broaden the scope and geographic
distribution of NIGMS training funds and is open only to:
a) institutions that currently do not have an NIGMS-funded institutional predoctoral T32 training program including
MSTP (with the exception of Behavioral-Biomedical Sciences Interface or Biostatistics), or
b) institutions with current NIGMS-funded predoctoral T32 training programs that propose to merge two or more of
their existing NIGMS-funded predoctoral training programs in basic biomedical sciences disciplines into a single
Medical Scientist Training Program (MSTP, leading to the combined M.D.-Ph.D. degree): Dr. Stefan Maas and Dr. Joe
The MSTP supports the integrated medical and graduate research training that is required for the investigation of
human diseases. It assures highly selected trainees a choice of a wide range of pertinent graduate programs in the
biological, chemical and physical sciences that, when combined with training in medicine, lead to the M.D.-Ph.D.
degree. Programs are encouraged to provide a breadth of doctoral research training opportunities consistent with
individual institutional strengths. In addition to the above disciplines, support of trainees in other disciplines
such as computer sciences, social and behavioral sciences, economics, epidemiology, public health, bioengineering,
biostatistics and bioethics is encouraged. Proposed MSTP programs should be flexible and adaptable in providing each
trainee with the appropriate background in the sciences relevant to medicine, yet be rigorous enough to enable
graduates to function independently in both basic research and clinical investigation.
This page last reviewed on
9/17/2019 1:40 PM
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