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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Culex quinquefasciatus mosquito larvae
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Mosquito larvae with genes edited by CRISPR swimming in water. Valentino Gantz, University of California, San Diego. View MediaCone snail shell
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A shell from the venomous cone snail Conus omaria, which lives in the Pacific and Indian oceans and eats other snails. Kerry Matz, University of Utah View MediaStatistical cartography
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Like a world of its own, this sphere represents all the known chemical reactions in the E. coli bacterium. Luis A. Nunes Amaral, Northwestern University View MediaFruit fly larvae brains showing tubulin
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Two fruit fly (Drosophila melanogaster) larvae brains with neurons expressing fluorescently tagged tubulin protein. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View MediaColor coding of the Drosophila brain - black background
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This image results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View MediaCRISPR Illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaDying melanoma cells
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Melanoma (skin cancer) cells undergoing programmed cell death, also called apoptosis. This process was triggered by raising the pH of the medium that the cells were growing in. Dylan T. Burnette, Vanderbilt University School of Medicine. View MediaYeast cells with nuclear envelopes and tubulin
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Yeast cells with nuclear envelopes shown in magenta and tubulin shown in light blue. The nuclear envelope defines the borders of the nucleus, which houses DNA. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View MediaCRISPR
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RNA incorporated into the CRISPR surveillance complex is positioned to scan across foreign DNA. Cryo-EM density from a 3Å reconstruction is shown as a yellow mesh. NRAMM National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View MediaAdvanced Photon Source (APS) at Argonne National Lab
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The intense X-rays produced by synchrotrons such as the Advanced Photon Source are ideally suited for protein structure determination. Southeast Collaboratory for Structural Genomics View Media800 MHz NMR magnet
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Scientists use nuclear magnetic spectroscopy (NMR) to determine the detailed, 3D structures of molecules. Asokan Anbanandam, University of Kansas View MediaColor-coded chromosomes
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By mixing fluorescent dyes like an artist mixes paints, scientists are able to color code individual chromosomes. Anna Jauch, Institute of Human Genetics, Heidelberg, Germany View MediaHawaiian bobtail squid
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An adult Hawaiian bobtail squid, Euprymna scolopes, swimming next to a submerged hand. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaCryo-ET cross-section of a rat pancreas cell
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On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a 3D, color-coded version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View MediaIntroduction to Genome Editing Using CRISPR/Cas9
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Genome editing using CRISPR/Cas9 is a rapidly expanding field of scientific research with emerging applications in disease treatment, medical therapeutics and bioenergy, just to name a few. Janet Iwasa View MediaLeading cells with light
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A blue laser beam turns on a protein that helps this human cancer cell move. Responding to the stimulus, the protein, called Rac1, first creates ruffles at the edge of the cell. Yi Wu, University of North Carolina View MediaMicrofluidic chip
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Microfluidic chips have many uses in biology labs. Jeff Hasty Lab, UC San Diego View MediaConfocal microscopy of perineuronal nets in the brain 2
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The photo shows a confocal microscopy image of perineuronal nets (PNNs), which are specialized extracellular matrix (ECM) structures in the brain. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaSingle-Molecule Imaging
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This is a super-resolution light microscope image taken by Hiro Hakozaki and Masa Hoshijima of NCMIR. Tom Deerinck, NCMIR View MediaPodocytes from a chronically diseased kidney
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This scanning electron microscope (SEM) image shows podocytes--cells in the kidney that play a vital role in filtering waste from the bloodstream--from a patient with chronic kidney disease. Olga Troyanskaya, Princeton University and Matthias Kretzler, University of Michigan View MediaA molecular interaction network in yeast 3
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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View MediaPlasma-Derived Membrane Vesicles
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This fiery image doesn’t come from inside a bubbling volcano. Instead, it shows animal cells caught in the act of making bubbles, or blebbing. Jeanne Stachowiak, University of Texas at Austin View MediaHuman embryonic stem cells on feeder cells
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This fluorescent microscope image shows human embryonic stem cells whose nuclei are stained green. Blue staining shows the surrounding supportive feeder cells. Michael Longaker lab, Stanford University School of Medicine, via CIRM View MediaCell-like compartments from frog eggs 4
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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View MediaAdult and juvenile Hawaiian bobtail squids
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An adult Hawaiian bobtail squid, Euprymna scolopes, (~4 cm) surrounded by newly hatched juveniles (~2 mm) in a bowl of seawater.Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
Color coding of the Drosophila brain - video
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This video results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View MediaChromium X-ray source
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In the determination of protein structures by X-ray crystallography, this unique soft (l = 2.29Å) X-ray source is used to collect anomalous scattering data from protein crystals containing light atoms The Southeast Collaboratory for Structural Genomics View MediaElectrostatic map of the adeno-associated virus
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The new highly efficient parallelized DelPhi software was used to calculate the potential map distribution of an entire virus, the adeno-associated virus, which is made up of more than 484,000 atoms. Emil Alexov, Clemson University View MediaTransmission electron microscopy showing cross-section of the node of Ranvier
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Nodes of Ranvier are short gaps in the myelin sheath surrounding myelinated nerve cells (axons). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaFinding one bug
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A nanometer-sized biosensor can detect a single deadly bacterium in tainted ground beef. How? Weihong Tan, University of Florida in Gainesville View MediaCRISPR illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaHeLa cells
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Scanning electron micrograph of an apoptotic HeLa cell. Zeiss Merlin HR-SEM. National Center for Microscopy and Imaging Research View MediaCRISPR Illustration Frame 3
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaSnowflake yeast 1
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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View MediaFruit fly ovaries
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Fruit fly (Drosophila melanogaster) ovaries with DNA shown in magenta and actin filaments shown in light blue. This image was captured using a confocal laser scanning microscope.Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media
Electrostatic map of human spermine synthase
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From PDB entry 3c6k, Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine. Emil Alexov, Clemson University View MediaStaphylococcus aureus aggregating upon contact with synovial fluid
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Staphylococcus aureus bacteria (green) grouping together upon contact with synovial fluid—a viscous substance found in joints. Paul Stoodley, The Ohio State University. View MediaColorful communication
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The marine bacterium Vibrio harveyi glows when near its kind. Bonnie Bassler, Princeton University View MediaArachnoidiscus diatom
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An Arachnoidiscus diatom with a diameter of 190µm. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaAxolotl showing nervous system
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The head of an axolotl—a type of salamander—that has been genetically modified so that its developing nervous system glows purple and its Schwann cell nuclei appear light blue. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View MediaModeling disease spread
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What looks like a Native American dream catcher is really a network of social interactions within a community. Stephen Eubank, University of Virginia Biocomplexity Institute (formerly Virginia Bioinformatics Institute) View MediaJack bean concanavalin A
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Crystals of jack bean concanavalin A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaMouse brain 2
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A mouse brain that was genetically modified so that subpopulations of its neurons glow. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View MediaScanning electron microscopy of the ECM on the surface of a calf muscle
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This image shows the extracellular matrix (ECM) on the surface of a soleus (lower calf) muscle in light brown and blood vessels in pink. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaIntasome
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Salk researchers captured the structure of a protein complex called an intasome (center) that lets viruses similar to HIV establish permanent infection in their hosts. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View MediaPetri dish
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The white circle in this image is a Petri dish, named for its inventor, Julius Richard Petri. H. Robert Horvitz and Dipon Ghosh, Massachusetts Institute of Technology. View MediaEnzyme transition states
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The molecule on the left is an electrostatic potential map of the van der Waals surface of the transition state for human purine nucleoside phosphorylase. Vern Schramm, Albert Einstein College of Medicine of Yeshiva University View MediaDNA replication origin recognition complex (ORC)
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A study published in March 2012 used cryo-electron microscopy to determine the structure of the DNA replication origin recognition complex (ORC), a semi-circular, protein complex (yellow) that recogni Huilin Li, Brookhaven National Laboratory View MediaAnnotated TEM cross-section of C. elegans (roundworm)
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The worm Caenorhabditis elegans is a popular laboratory animal because its small size and fairly simple body make it easy to study. Piali Sengupta, Brandeis University View MediaStaphylococcus aureus aggregates on microstructured titanium surface
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Groups of Staphylococcus aureus bacteria (blue) attached to a microstructured titanium surface (green) that mimics an orthopedic implant used in joint replacement. Paul Stoodley, The Ohio State University. View Media