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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Calling Cards in a mouse brain

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The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. Allen Yen, Lab of Joseph Dougherty, Washington University School of Medicine in St. Louis. View Media

Scanning electron microscopy of the ECM on the surface of a calf muscle

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This image shows the extracellular matrix (ECM) on the surface of a soleus (lower calf) muscle in light brown and blood vessels in pink. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Cytoscape network wiring diagram 2

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This image integrates the thousands of known molecular and genetic interactions happening inside our bodies using a computer program called Cytoscape. Trey Ideker, University of California, San Diego View Media

Scanning electron microscopy of collagen fibers

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This image shows collagen, a fibrous protein that's the main component of the extracellular matrix (ECM). Collagen is a strong, ropelike molecule that forms stretch-resistant fibers. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Math from the heart

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Watch a cell ripple toward a beam of light that turns on a movement-related protein. View Media

Annotated TEM cross-section of C. elegans (roundworm)

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The worm Caenorhabditis elegans is a popular laboratory animal because its small size and fairly simple body make it easy to study. Piali Sengupta, Brandeis University View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 5

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

A Growing Bacterial Biofilm

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A growing Vibrio cholerae (cholera) biofilm. Cholera bacteria form colonies called biofilms that enable them to resist antibiotic therapy within the body and other challenges to their growth. Jing Yan, Ph.D., and Bonnie Bassler, Ph.D., Department of Molecular Biology, Princeton University, Princeton, NJ. View Media

Assembly of the HIV capsid

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The HIV capsid is a pear-shaped structure that is made of proteins the virus needs to mature and become infective. John Grime and Gregory Voth, The University of Chicago View Media

Single-cell “radios” video

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Individual cells are color-coded based on their identity and signaling activity using a protein circuit technology developed by the Coyle Lab. Scott Coyle, University of Wisconsin-Madison. View Media

Computer sketch of bird-and-flower DNA origami

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A computer-generated sketch of a DNA origami folded into a flower-and-bird structure. See also related image 3690. Hao Yan, Arizona State University View Media

Snowflake DNA origami

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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. The image is featured on Biomedical Beat blog post Cool Images: A Holiday-Themed Collection. Hao Yan, Arizona State University View Media

Research mentor and student

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A research mentor (Lori Eidson) and student (Nina Waldron, on the microscope) were 2009 members of the BRAIN (Behavioral Research Advancements In Neuroscience) program at Georgia State University in A Elizabeth Weaver, Georgia State University View Media

LONI movie

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Related to image 5871. View Media

Yeast cells entering mitosis

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Yeast cells entering mitosis, also known as cell division. The green and magenta dots are two proteins that play important roles in mitosis. They show where the cells will split. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media

Cell-like compartments emerging from scrambled frog eggs

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Cell-like compartments spontaneously emerge from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media

ATP Synthase

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Atomic model of the membrane region of the mitochondrial ATP synthase built into a cryo-EM map at 3.6 Å resolution. ATP synthase is the primary producer of ATP in aerobic cells. Bridget Carragher, <a href="http://nramm.nysbc.org/">NRAMM National Resource for Automated Molecular Microscopy</a> View Media

Dividing yeast cells with nuclear envelopes and spindle pole bodies

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Time-lapse video of yeast cells undergoing cell division. Nuclear envelopes are shown in green, and spindle pole bodies, which help pull apart copied genetic information, are shown in magenta. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media

Fat cells (red) and blood vessels (green)

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A mouse's fat cells (red) are shown surrounded by a network of blood vessels (green). Daniela Malide, National Heart, Lung, and Blood Institute, National Institutes of Health View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 2

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

DNase

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Crystals of DNase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Rat Hippocampus

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This image of the hippocampus was taken with an ultra-widefield high-speed multiphoton laser microscope. Tom Deerinck, NCMIR View Media

Cell-like compartments from frog eggs 6

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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media

Group of Culex quinquefasciatus mosquito larvae

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Mosquito larvae with genes edited by CRISPR. Valentino Gantz, University of California, San Diego. View Media

Rotavirus structure

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This image shows a computer-generated, three-dimensional map of the rotavirus structure. This virus infects humans and other animals and causes severe diarrhea in infants and young children. Bridget Carragher, The Scripps Research Institute, La Jolla, CA View Media

Rabbit GPDA

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A crystal of rabbit GPDA protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Two mouse fibroblast cells

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Two mouse fibroblasts, one of the most common types of cells in mammalian connective tissue. They play a key role in wound healing and tissue repair. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media

Cone snail shell

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A shell from the venomous cone snail Conus omaria, which lives in the Pacific and Indian oceans and eats other snails. Kerry Matz, University of Utah View Media

Cells lining the trachea

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In this image, viewed with a ZEISS ORION NanoFab microscope, the community of cells lining a mouse airway is magnified more than 10,000 times. Eva Mutunga and Kate Klein, University of the District of Columbia and National Institute of Standards and Technology View Media

Endoplasmic reticulum abnormalities 2

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Human cells with the gene that codes for the protein FIT2 deleted. After an experimental intervention, they are expressing a nonfunctional version of FIT2, shown in green. Michel Becuwe, Harvard University. View Media

Myosin V binding to actin

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This simulation of myosin V binding to actin was created using the software tool Protein Mechanica. Simbios, NIH Center for Biomedical Computation at Stanford View Media

Adult Hawaiian bobtail squid burying in the sand

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Each morning, the nocturnal Hawaiian bobtail squid, Euprymna scolopes, hides from predators by digging into the sand. At dusk, it leaves the sand again to hunt. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

Protein crystals

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Structural biologists create crystals of proteins, shown here, as a first step in a process called X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Ribbon diagram of a cefotaxime-CCD-1 complex

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Honeybee brain

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Insect brains, like the honeybee brain shown here, are very different in shape from human brains. Gene Robinson, University of Illinois at Urbana-Champaign. View Media

Introduction to Genome Editing Using CRISPR/Cas9

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Genome editing using CRISPR/Cas9 is a rapidly expanding field of scientific research with emerging applications in disease treatment, medical therapeutics and bioenergy, just to name a few. Janet Iwasa View Media

Snowflake yeast 3

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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View Media

Microtubules in hippocampal neurons

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Microtubules (magenta) in neurons of the hippocampus, a part of the brain involved in learning and memory. Microtubules are strong, hollow fibers that provide structural support to cells. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media

CRISPR Illustration Frame 4

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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media

Confocal microscopy image of two Drosophila ovarioles

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Ovarioles in female insects are tubes in which egg cells (called oocytes) form at one end and complete their development as they reach the other end of the tube. 2004 Olympus BioScapes Competition View Media

Mouse brain 1

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A mouse brain that was genetically modified so that subpopulations of its neurons glow. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media

Cell division and cell death

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Two cells over a 2-hour period. The one on the bottom left goes through programmed cell death, also known as apoptosis. The one on the top right goes through cell division, also called mitosis. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media

Snowflake yeast 1

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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View Media

Nano-rainbow

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These vials may look like they're filled with colored water, but they really contain nanocrystals reflecting different colors under ultraviolet light. Shuming Nie, Emory University View Media

Correlative imaging by annotation with single molecules (CIASM) process

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These images illustrate a technique combining cryo-electron tomography and super-resolution fluorescence microscopy called correlative imaging by annotation with single molecules (CIASM). Peter Dahlberg, Stanford University. View Media

Relapsing fever bacterium (gray) and red blood cells

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Relapsing fever is caused by a bacterium and transmitted by certain soft-bodied ticks or body lice. The disease is seldom fatal in humans, but it can be very serious and prolonged. NIAID View Media

HIV Capsid

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This image is a computer-generated model of the approximately 4.2 million atoms of the HIV capsid, the shell that contains the virus' genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View Media

Mouse retina

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What looks like the gossamer wings of a butterfly is actually the retina of a mouse, delicately snipped to lay flat and sparkling with fluorescent molecules. Tom Deerinck and Keunyoung (“Christine”) Kim, NCMIR View Media

Multivesicular bodies containing intralumenal vesicles assemble at the vacuole 2

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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View Media

Yeast cells with Fimbrin Fim1

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Yeast cells with the protein Fimbrin Fim1 shown in magenta. This protein plays a role in cell division. This image was captured using wide-field microscopy with deconvolution.
Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media