Image and Video Gallery

This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Artificial cilia exhibit spontaneous beating

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Researchers have created artificial cilia that wave like the real thing. Zvonimir Dogic View Media

Optic nerve astrocytes

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Astrocytes in the cross section of a human optic nerve head Tom Deerinck and Keunyoung (“Christine”) Kim, NCMIR View Media

dUTP pyrophosphatase from M. tuberculosis

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Model of an enzyme, dUTP pyrophosphatase, from Mycobacterium tuberculosis. Drugs targeted to this enzyme might inhibit the replication of the bacterium that causes most cases of tuberculosis. Mycobacterium Tuberculosis Center, PSI View Media

Heat shock protein complex from Methanococcus jannaschii

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Model based on X-ray crystallography of the structure of a small heat shock protein complex from the bacteria, Methanococcus jannaschii. Berkeley Structural Genomics Center, PSI-1 View Media

Snowflake DNA origami

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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. The image is featured on Biomedical Beat blog post Cool Images: A Holiday-Themed Collection. Hao Yan, Arizona State University View Media

Nuclear Lamina

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The 3D single-molecule super-resolution reconstruction of the entire nuclear lamina in a HeLa cell was acquired using the TILT3D platform. Anna-Karin Gustavsson, Ph.D. View Media

ATP Synthase

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Atomic model of the membrane region of the mitochondrial ATP synthase built into a cryo-EM map at 3.6 Å resolution. ATP synthase is the primary producer of ATP in aerobic cells. Bridget Carragher, <a href="http://nramm.nysbc.org/">NRAMM National Resource for Automated Molecular Microscopy</a> View Media

Cellular aging

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A protein called tubulin (green) accumulates in the center of a nucleus (outlined in pink) from an aging cell. Maximiliano D'Angelo and Martin Hetzer, Salk Institute View Media

Structure of heme, top view

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Molecular model of the struture of heme. Heme is a small, flat molecule with an iron ion (dark red) at its center. Rachel Kramer Green, RCSB Protein Data Bank View Media

Beta2-adrenergic receptor protein

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Crystal structure of the beta2-adrenergic receptor protein. The Stevens Laboratory, The Scripps Research Institute View Media

Precise development in the fruit fly embryo

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This 2-hour-old fly embryo already has a blueprint for its formation, and the process for following it is so precise that the difference of just a few key molecules can change the plans. Thomas Gregor, Princeton University View Media

Intasome

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Salk researchers captured the structure of a protein complex called an intasome (center) that lets viruses similar to HIV establish permanent infection in their hosts. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media

Disrupted vascular development in frog embryos

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Disassembly of vasculature in kdr:GFP frogs following addition of 250 µM TBZ. Related to images 3404 and 3505. Hye Ji Cha, University of Texas at Austin View Media

Morphine Structure

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The chemical structure of the morphine molecule Judy Coyle, Donald Danforth Plant Science Center View Media

Life of an AIDS virus (with labels and stages)

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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View Media

Weblike sheath covering developing egg chambers in a giant grasshopper

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The lubber grasshopper, found throughout the southern United States, is frequently used in biology classes to teach students about the respiratory system of insects. Kevin Edwards, Johny Shajahan, and Doug Whitman, Illinois State University. View Media

Kappa opioid receptor

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The receptor is shown bound to an antagonist, JDTic. Raymond Stevens, The Scripps Research Institute View Media

Crane fly spermatocyte undergoing meiosis

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A crane fly spermatocyte during metaphase of meiosis-I, a step in the production of sperm. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Nuclear Lamina – Three Views

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Three views of the entire nuclear lamina of a HeLa cell produced by tilted light sheet 3D single-molecule super-resolution imaging using a platform termed TILT3D. Anna-Karin Gustavsson, Ph.D. View Media

Seeing signaling protein activation in cells 04

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Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins, regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View Media

Molecular model of freshly made Rous sarcoma virus (RSV)

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Viruses have been the foes of animals and other organisms for time immemorial. Boon Chong Goh, University of Illinois at Urbana-Champaign View Media

Pig trypsin crystal

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A crystal of pig trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

RNA folding in action

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An RNA molecule dynamically refolds itself as it is being synthesized. When the RNA is short, it ties itself into a “knot” (dark purple). Julius Lucks, Northwestern University View Media

Bovine milk alpha-lactalbumin (1)

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A crystal of bovine milk alpha-lactalbumin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Oligoendopeptidase F from B. stearothermophilus

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Crystal structure of oligoendopeptidase F, a protein slicing enzyme from Bacillus stearothermophilus, a bacterium that can cause food products to spoil. Accelerated Technologies Center for Gene to 3D Structure/Midwest Center for Structural Genomics View Media

Seeing signaling protein activation in cells 01

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Life of an AIDS virus

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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View Media

Kinases

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Kinases are enzymes that add phosphate groups (red-yellow structures) to proteins (green), assigning the proteins a code. Crabtree + Company View Media

Structure of telomerase

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Scientists recently discovered the full molecular structure of telomerase, an enzyme important to aging and cancer. Jiansen Jiang, Edward J. Miracco, Z. Hong Zhou and Juli Feigon, University of California, Los Angeles; Kathleen Collins, University of California, Berkeley View Media

Plastic-eating enzymes

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PETase enzyme degrades polyester plastic (polyethylene terephthalate, or PET) into monohydroxyethyl terephthalate (MHET). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

CCP enzyme

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The enzyme CCP is found in the mitochondria of baker’s yeast. Scientists study the chemical reactions that CCP triggers, which involve a water molecule, iron, and oxygen. Protein Data Bank. View Media

Serum albumin structure 1

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Serum albumin (SA) is the most abundant protein in the blood plasma of mammals. SA has a characteristic heart-shape structure and is a highly versatile protein. Wladek Minor, University of Virginia View Media

Protein involved in cell division from Mycoplasma pneumoniae

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Model of a protein involved in cell division from Mycoplasma pneumoniae. This model, based on X-ray crystallography, revealed a structural domain not seen before. Berkeley Structural Genomics Center, PSI View Media

Himastatin

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A model of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

CRISPR

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RNA incorporated into the CRISPR surveillance complex is positioned to scan across foreign DNA. Cryo-EM density from a 3Å reconstruction is shown as a yellow mesh. NRAMM National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media

A Growing Bacterial Biofilm

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A growing Vibrio cholerae (cholera) biofilm. Cholera bacteria form colonies called biofilms that enable them to resist antibiotic therapy within the body and other challenges to their growth. Jing Yan, Ph.D., and Bonnie Bassler, Ph.D., Department of Molecular Biology, Princeton University, Princeton, NJ. View Media

Dopamine D3 receptor

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The receptor is shown bound to an antagonist, eticlopride Raymond Stevens, The Scripps Research Institute View Media

Magnesium transporter protein from E. faecalis

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Structure of a magnesium transporter protein from an antibiotic-resistant bacterium (Enterococcus faecalis) found in the human gut. New York Structural GenomiX Consortium View Media

Full-length serotonin receptor (ion channel)

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A 3D reconstruction, created using cryo-electron microscopy, of an ion channel known as the full-length serotonin receptor in complex with the antinausea drug granisetron (orange). Sudha Chakrapani, Case Western Reserve University School of Medicine. View Media

Thymidylate synthase complementing protein from Thermotoga maritime

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A model of thymidylate synthase complementing protein from Thermotoga maritime. Joint Center for Structural Genomics, PSI View Media

G switch (with labels and stages)

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The G switch allows our bodies to respond rapidly to hormones. G proteins act like relay batons to pass messages from circulating hormones into cells. Crabtree + Company View Media

RNase A (2)

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A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Cryo-EM reveals how the HIV capsid attaches to a human protein to evade immune detection

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The illustration shows the capsid of human immunodeficiency virus (HIV) whose molecular features were resolved with cryo-electron microscopy (cryo-EM). Juan R. Perilla, University of Illinois at Urbana-Champaign View Media

Cytochrome structure with anticancer drug

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This image shows the structure of the CYP17A1 enzyme (ribbons colored from blue N-terminus to red C-terminus), with the associated heme colored black. Emily Scott, University of Kansas View Media

Dynein moving along microtubules

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Dynein (green) is a motor protein that “walks” along microtubules (red, part of the cytoskeleton) and carries its cargo along with it. This video was captured through fluorescence microscopy. Morgan DeSantis, University of Michigan. View Media

G switch (with labels)

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The G switch allows our bodies to respond rapidly to hormones. G proteins act like relay batons to pass messages from circulating hormones into cells. Crabtree + Company View Media

Molecular interactions

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This network map shows molecular interactions (yellow) associated with a congenital condition that causes heart arrhythmias and the targets for drugs that alter these interactions (red and blue). Ravi Iyengar, Mount Sinai School of Medicine View Media

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