Image Gallery: Structure of Glutamate Dehydrogenase

ID
3421
Some children are born with a mutation in a regulatory site on this enzyme that causes them to over-secrete insulin when they consume protein. We found that a compound from green tea (shown in the stick figure and by the yellow spheres on the enzyme) is able to block this hyperactivity when given to animals with this disorder.
Source
Judy Coyle, Donald Danforth Plant Science Center