The 2017 Training, Workforce Development, and Diversity (TWD) Program Directors’ Meeting, organized through a grant to the Federation of Associations for Experimental Biology, took place June 18-21 in Baltimore. This biennial meeting brought together the community of faculty, staff and administrators who manage TWD undergraduate and predoctoral training programs across the nation to network, share best practices for program improvement and connect with NIGMS staff. This year, participants presented more than 100 posters. Plenary sessions and keynote talks described innovative approaches for training and evaluation, efforts to enhance diversity in the biomedical workforce and more. Highlights included:

• Alison Gammie, director of NIGMS’ TWD division, outlined the new predoctoral T32 funding opportunity announcement (FOA) in her presentation. The FOA will emphasize cultivating a diverse pool of well-trained scientists and will focus on skills and career development, the importance of scientific rigor and reproducibility, and the value of inclusive and supportive training environments. It is scheduled for publication this fall.
• Principal investigators of administrative supplements to NIGMS predoctoral training grants presented their approaches to modernizing biomedical graduate education through increased focus on scientific rigor, career and skill development, and training opportunities.
• Melanie Sinche, director of education at the Jackson Laboratory for Genomic Medicine and author of “Next Gen PhD: A Guide to Career Paths in Science,” shared her research on recent STEM Ph.D. graduates’ career pathways. She found that the majority of recent STEM Ph.D. graduates who responded to her survey expressed satisfaction with their work, and they chose their employment primarily for “intellectual challenge” and “flexibility.”
• Erin Dolan, a professor at the University of Georgia, talked about effective strategies for science education. Citing a variety of references, Dolan presented on how the research training community can help students develop interests and careers in the sciences by incorporating models from educational research and social cognitive career theory. This approach is intended to nurture greater enthusiasm for science because it’s based on how students learn and make career decisions. Later, members of the Diversity Program Consortium’s Coordination and Evaluation Center led a workshop on evaluation techniques and shared some tools with attendees that may aid in more effectively evaluating training programs.
• In his Message from the Director, Jon Lorsch included an overview of ongoing NIGMS priorities, including the expansion of the Maximizing Investigators’ Research Award (MIRA) program. He also announced that NIGMS is the new home for the Science Education Partnership Award (SEPA) program, which supports educational and career activities for pre-K to grade 12 students, as well as other public outreach programming. SEPA strongly complements the rest of NIGMS’ workforce diversity and training portfolio. Examples of SEPA projects include mobile laboratories  that bring science to rural communities, professional development for teachers and media-based projects like the PBS NewsHour Student Reporting Labs.

To view more of the presentations and to access abstracts for the poster sessions, please visit the 2017 TWD Program Directors’ Meeting resources page.

UPDATE: The slides from the Bridges Applicants Webinar have been posted. Are you preparing an institutional Bridges to the Baccalaureate grant or Bridges to the Doctorate grant application? If so, you may have questions about the funding opportunity announcements, data tables and FORMS-D application package required for the upcoming September 25 application due date. We’re offering a webinar (link no longer available) to discuss these topics on Thursday, August 10, from 2:00-3:30 p.m. EDT. You may send questions to us (Mercedes Rubio or Patrick H. Brown) before the webinar or post them live in the chat box during the event. If you’re away from your computer, you can access the webinar from a mobile device or listen to a voice-only option by dialing 1-888-469-1681 from anywhere in the United States or Canada and entering the participant passcode 4928788. Slides will be posted on the Bridges to the Baccalaureate website and Bridges to the Doctorate website following the event. We look forward to talking to you about the Bridges programs.

NIGMS has a longstanding commitment to developing the next generation of biomedical scientists through a variety of programs, including the M.D.-Ph.D. dual degree Medical Scientist Training Program (MSTP). This program provides Ruth L. Kirschstein Institutional Predoctoral Training Grant (T32) awards to medical institutions that are responsible for training physician scientists. The Physician-Scientist Workforce Working Group Report of NIH’s Advisory Committee to the Director highlighted the decline of physician scientists as a percentage of overall NIH principal investigators. NIH data presented at the 50th Anniversary Medical Scientist Training Program Symposium showed that while earlier cohorts of MSTP trainees were highly successful in achieving independent research careers and NIH grant support, more recent graduates have been less successful. Many factors may contribute to this difference, including lengthening of the post-M.D.-Ph.D. training period before achieving independence and increased competition of investigators for limited research funds and positions. We are seeking input from the biomedical research community and other interested groups through a Request for Information (RFI) on strategies and ideas for the modernization of physician-scientist training that can be addressed through the MSTP. More specific topics are included in the RFI, but examples of broad areas of interest are:

• Trainees (e.g., time of recruitment to the MSTP, diversity of the applicant pool and selection criteria)
• Financing/funding (e.g., how different M.D.-Ph.D. funding models influence the range of institutions that apply for MSTP support, the pool of trainees and the trainees’ commitment to research careers)
• Dual-degree training (e.g., time-to-degree, integration of curriculum, training areas, mentoring and career advising)
• NIGMS management of MSTP grants (e.g., size, number and distribution of training programs; evaluation of outcomes; and peer review)
• Anything else specific to MSTP training that you feel is important for NIH to consider with respect to enhancing M.D.-Ph.D. training and the persistence of physician-scientist trainees in research careers (note that changes in post-M.D.-Ph.D. training and future research support are outside of the scope of this RFI)

Responses can be submitted via an online form and can be anonymous. The due date for providing input is August 9, 2017.

For students in the biomedical sciences, attending conferences is a chance to share ideas and research experiences with colleagues from across the country, while learning about educational and career opportunities and building identities as scientists. Outcomes from student conference attendance may also help us to learn how students build and maintain scientific identities. At conferences over the past two years, we have witnessed undergraduate trainees from the more recently-established Building Infrastructure Leading to Diversity (BUILD) program joining colleagues from long-running NIGMS-supported grants, like Research Initiative for Scientific Enhancement (RISE) and Maximizing Access to Research Careers (MARC).

Since BUILD is a fairly new program, it’s been great to see how quickly its trainees have embraced the opportunities conferences have to offer, from simply meeting other program trainees and sharing stories about their research to making valuable networking connections. BUILD, established in 2014, is a component of the Diversity Program Consortium (DPC), which also includes the National Research Mentoring Network (NRMN) and the Coordination and Evaluation Center (CEC). The DPC is part of a broad, trans-NIH strategy to address new ways to promote diversity in the biomedical research workforce.

In recent years, BUILD trainees have been in high attendance at the NIGMS-supported Society for Advancement of Chicanos/Hispanics and Native Americans in Science (SACNAS) conference and the Annual Biomedical Research Conference for Minority Students (ABRCMS). These conferences focus on broadening participation in biomedical research and introduce students to groundbreaking scientists.

During the BUILD networking sessions at both meetings, we heard students’ stories about their research and programs. We also had the opportunity to witness an element of students developing scientific identities—trading business cards.

Many BUILD students also made presentations on their research at the 2016 SACNAS and ABRCMS meetings, and eight of them received awards for posters and oral presentations. These awards are based on a variety of criteria, including knowledge of a subject area as well as experimental design. Because the DPC’s BUILD programs introduce undergraduate students to research through hands-on lab experience, it’s great to see that students are sharing their research findings, taking part in poster sessions and being recognized for their efforts.

Students’ interactions during networking sessions and scientific presentations complement another DPC goal: providing role models and mentors to students from a wide variety of backgrounds. Because evaluating program outcomes is integral to the DPC, we are evaluating whether these kinds of interactions help students persist in science careers and develop identities as scientists. It is our hope that what we learn from DPC interventions—such as promoting conference attendance among students—can be scaled to fit a larger audience and benefit students in other training programs.

UPDATE: The video and slides from the PRAT Program Webinar have been posted. We’re hosting a webinar for potential applicants to the PRAT Program on Tuesday, March 28, from 12:00-1:30 p.m. EDT. PRAT is a three-year program providing outstanding laboratory research experiences in NIH’s Intramural Research Program (IRP), access to NIH's extensive resources, mentorship, career development activities and networking. The program places special emphasis on training fellows in basic biomedical research areas including cell biology, biophysics, genetics, developmental biology, pharmacology, physiology, biological chemistry, computational biology, immunology, neuroscience, technology development and bioinformatics. The next receipt date for applications is October 3, 2017.  Applicants can be graduate students considering postdoctoral research opportunities or postdoctoral fellows with no more than two years of postdoctoral research experience by the time of appointment to the PRAT program (late summer 2018). All applications require connecting with an investigator in the NIH IRP in advance of writing the application. To attend the webinar, join the Skype meeting (link no longer available) shortly before 12:00 p.m. EDT and enter the conference ID 8368072. You can also attend by phone by calling 301-480-4255. Slides will be posted on the PRAT website following the event. We look forward to talking with you about the PRAT Program.

Last year, we launched the NIGMS Director’s Early Career Investigator Lecture series. Open to everyone in the scientific community, the lectures are directed at undergraduate students to introduce them to cutting-edge science while inspiring them to pursue biomedical research careers. The series also highlights the achievements of some of NIGMS’ early career grantees. I’m excited to share that the 2017 lecture will be presented by Namandjé Bumpus, Ph.D., associate professor of medicine-division of clinical pharmacology at Johns Hopkins University School of Medicine. Namandjé is an NIGMS-funded recipient of the Presidential Early Career Award for Scientists and Engineers. Her lecture, “Drug Metabolism, Pharmacogenetics and the Quest to Personalize HIV Treatment and Prevention,” will take place on the NIH campus on Wednesday, April 5, from 2:00-3:00 p.m. EDT. It will be videocast and archived on the NIH videocasting site.

UPDATE: The slides from the RISE Program Applicants Webinar have been posted. If you’re preparing an institutional RISE grant application, you might have questions about the funding opportunity announcement and data tables required for the upcoming May 25 receipt date. We’ll be available to discuss these topics during a webinar on Thursday, April 6, from 2:00-4:00 p.m. EDT. You may send questions before the webinar or post them in the chat box during the event. To access the webinar, visit the WebEx Meeting page (link no longer available) and enter meeting number 624 498 694 and the password “RISE2017.” If you are unable to attend online, you can join by phone by calling 1-877-668-4493 from anywhere in the United States or Canada and entering the meeting number above. We look forward to talking to you about the RISE program.

UPDATE: The slides from the MARC U-STAR program applicants Webinar have been posted. If you’re preparing an institutional MARC U-STAR grant application, you might have questions about the funding opportunity announcement and data tables required for the upcoming May 25 receipt date. We’ll be available to discuss these topics during a webinar on Wednesday, March 22, from 2:00-3:30 p.m. EDT. You may send questions to me before the webinar or post them in the chat box during the event. To access the webinar, visit the WebEx Meeting page (link no longer available) and enter meeting number 624 460 843 and the password “NIGMS.” We look forward to talking to you about the MARC U-STAR program.

Each year, NIH nominates outstanding young scientists for the Presidential Early Career Award for Scientists and Engineers (PECASE), the highest honor bestowed by the U.S. government to scientists beginning their independent research careers. The scientists are selected for their innovative research record, potential to continue on this productive route and community service activities. Among this year’s PECASE recipients (nominated in 2014) are two NIGMS grantees, Tufts University’s Aimee Shen (who started her career at the University of Vermont) and Montana State University’s Blake Wiedenheft (who was the inaugural NIGMS Director’s Early Career Investigator Lecturer). Both scientists launched their labs with support from our Institutional Development Award (IDeA) program, which fosters health-related research and enhances the competitiveness of investigators at institutions in states with historically low levels of NIH funding.

Below, they answer questions about their research and community service efforts, offer advice to other early career scientists, and share their experiences with the IDeA program.

What is the focus of your research?

Blake Wiedenheft: Viruses that infect bacteria (i.e., bacteriophages) are the most abundant biological entities on earth. The selective pressures imposed by these pervasive predators have a profound impact on the composition and the behavior of microbial communities in every ecological setting. In my lab, we rely on a combination of techniques from bioinformatics, genetics, biochemistry and structural biology to understand the mechanisms that bacteria use to defend themselves from viral infection.

Aimee Shen: My lab studies Clostridium difficile, the leading cause of healthcare-associated infection in the United States. C. difficile forms metabolically dormant cells known as spores that allow the microbe to survive exit from the gastrointestinal tract of a mammalian host. My research is directed at understanding how C. difficile spores form in order to transmit infection and how they germinate and transform into disease-causing cells to initiate infection.

After attending the Diversity Program Consortium (DPC) annual meeting in mid-October and learning about the progress the consortium has made and its future plans, we’re feeling energized as we begin the third year of this grant. The DPC, supported by the NIH Common Fund and managed by NIGMS, is a cooperative agreement focused on finding the best ways to improve research training and mentoring in the biomedical sciences and on engaging a more diverse field of individuals in biomedical research careers. The consortium includes three interconnected programs: Building Infrastructure Leading to Diversity (BUILD), the National Research Mentoring Network (NRMN) and the Coordination and Evaluation Center (CEC). The annual meeting brought together over 100 representatives from NIH and each grantee site to discuss DPC achievements, challenges and opportunities. The agenda, organized by the CEC, included two full days of presentations and breakout sessions.