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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Two-headed Xenopus laevis tadpole
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Xenopus laevis, the African clawed frog, has long been used as a research organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View MediaLily mitosis 12
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaFrom DNA to Protein
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Nucleotides in DNA are copied into RNA, where they are read three at a time to encode the amino acids in a protein. Many parts of a protein fold as the amino acids are strung together. Crabtree + Company View MediaXenopus laevis egg
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Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. Michael Klymkowsky, University of Colorado, Boulder View MediaDNA replication origin recognition complex (ORC)
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A study published in March 2012 used cryo-electron microscopy to determine the structure of the DNA replication origin recognition complex (ORC), a semi-circular, protein complex (yellow) that recogni Huilin Li, Brookhaven National Laboratory View MediaAverage teen circadian cycle
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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. Typical circadian rhythms lead to high energy during the middle of the day (10 a.m. NIGMS View MediaCentral dogma, illustrated
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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View MediaRecombinant DNA
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To splice a human gene into a plasmid, scientists take the plasmid out of an E. coli bacterium, cut the plasmid with a restriction enzyme, and splice in human DNA. Crabtree + Company View MediaChromosome inside nucleus
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The long, stringy DNA that makes up genes is spooled within chromosomes inside the nucleus of a cell. Crabtree + Company View MediaFruit fly ovarioles
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Three fruit fly (Drosophila melanogaster) ovarioles (yellow, blue, and magenta) with egg cells visible inside them. Ovarioles are tubes in the reproductive systems of female insects. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View MediaCRISPR Illustration Frame 3
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaBottles of warfarin
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In 2007, the FDA modified warfarin's label to indicate that genetic makeup may affect patient response to the drug. The widely used blood thinner is sold under the brand name Coumadin®. Alisa Machalek, NIGMS/NIH View MediaGenetically identical mycobacteria respond differently to antibiotic 2
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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View MediaFluorescence in situ hybridization (FISH) in mouse ES cells shows DNA interactions
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Researchers used fluorescence in situ hybridization (FISH) to confirm the presence of long range DNA-DNA interactions in mouse embryonic stem cells. Kathrin Plath, University of California, Los Angeles View MediaRNA Polymerase II
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NIGMS-funded researchers led by Roger Kornberg solved the structure of RNA polymerase II. David Bushnell, Ken Westover and Roger Kornberg, Stanford University View MediaPlanarian stem cell colony
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Planarians are freshwater flatworms that have powerful abilities to regenerate their bodies, which would seem to make them natural model organisms in which to study stem cells. Peter Reddien, Whitehead Institute View MediaFrom DNA to Protein (labeled)
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The genetic code in DNA is transcribed into RNA, which is translated into proteins with specific sequences. Crabtree + Company View MediaCross section of a Drosophila melanogaster pupa lacking Draper
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In the absence of the engulfment receptor Draper, salivary gland cells (light blue) persist in the thorax of a developing Drosophila melanogaster pupa. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View MediaPrecise development in the fruit fly embryo
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This 2-hour-old fly embryo already has a blueprint for its formation, and the process for following it is so precise that the difference of just a few key molecules can change the plans. Thomas Gregor, Princeton University View MediaLily mitosis 02
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaPollen grains: male germ cells in plants and a cause of seasonal allergies
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Those of us who get sneezy and itchy-eyed every spring or fall may have pollen grains, like those shown here, to blame. Edna, Gil, and Amit Cukierman, Fox Chase Cancer Center, Philadelphia, Pa. View MediaCRISPR Illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaHippocampal neuron in culture
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Hippocampal neuron in culture. Dendrites are green, dendritic spines are red and DNA in cell's nucleus is blue. Shelley Halpain, UC San Diego View MediaTelomeres
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The 46 human chromosomes are shown in blue, with the telomeres appearing as white pinpoints. Hesed Padilla-Nash and Thomas Ried, the National Cancer Institute, a part of NIH View MediaHaplotypes
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Haplotypes are combinations of gene variants that are likely to be inherited together within the same chromosomal region. Crabtree + Company View MediaEndoplasmic reticulum abnormalities
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Human cells with the gene that codes for the protein FIT2 deleted. Green indicates an endoplasmic reticulum (ER) resident protein. Michel Becuwe, Harvard University. View MediaCulex quinquefasciatus mosquito larvae
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Mosquito larvae with genes edited by CRISPR swimming in water. Valentino Gantz, University of California, San Diego. View MediaDicty fruit
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Dictyostelium discoideum is a microscopic amoeba. A group of 100,000 form a mound as big as a grain of sand. Featured in The New Genetics. View MediaDNA replication illustration (with labels)
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During DNA replication, each strand of the original molecule acts as a template for the synthesis of a new, complementary DNA strand. Crabtree + Company View MediaCRISPR Illustration Frame 2
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaDisease-susceptible Arabidopsis leaf
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This is a magnified view of an Arabidopsis thaliana leaf after several days of infection with the pathogen Hyaloperonospora arabidopsidis. Jeff Dangl, University of North Carolina, Chapel Hill View MediaHIV enzyme
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These images model the molecular structures of three enzymes with critical roles in the life cycle of the human immunodeficiency virus (HIV). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaCRISPR Illustration Frame 4
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaCentral dogma, illustrated (with labels and numbers for stages)
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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View MediaEarly development in Arabidopsis
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Early on, this Arabidopsis plant embryo picks sides: While one end will form the shoot, the other will take root underground. Zachery R. Smith, Jeff Long lab at the Salk Institute for Biological Studies View MediaArabidopsis leaf injected with a pathogen
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This is a magnified view of an Arabidopsis thaliana leaf eight days after being infected with the pathogen Hyaloperonospora arabidopsidis, which is closely related to crop pathogens that Jeff Dangl, University of North Carolina, Chapel Hill View MediaMapping human genetic variation
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This map paints a colorful portrait of human genetic variation around the world. Noah Rosenberg and Martin Soave, University of Michigan View MediaAlternative splicing
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Arranging exons in different patterns, called alternative splicing, enables cells to make different proteins from a single gene. Crabtree + Company View MediaCircadian rhythms and the SCN
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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. NIGMS View MediaMeiosis illustration (with labels)
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Meiosis is the process whereby a cell reduces its chromosomes from diploid to haploid in creating eggs or sperm. Crabtree + Company View MediaDeveloping zebrafish fin
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Originally from the waters of India, Nepal, and neighboring countries, zebrafish can now be found swimming in science labs (and home aquariums) throughout the world. Jessica Plavicki View MediaBrain showing hallmarks of Alzheimer's disease
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Along with blood vessels (red) and nerve cells (green), this mouse brain shows abnormal protein clumps known as plaques (blue). Alvin Gogineni, Genentech View MediaCRISPR illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaRetroviruses as fossils
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DNA doesn't leave a fossil record in stone, the way bones do. Instead, the DNA code itself holds the best evidence for organisms' genetic history. Emily Harrington, science illustrator View MediaPulsating response to stress in bacteria
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By attaching fluorescent proteins to the genetic circuit responsible for B. subtilis's stress response, researchers can observe the cells' pulses as green flashes. Michael Elowitz, Caltech University View MediaDNA and actin in cultured fibroblast cells
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DNA (blue) and actin (red) in cultured fibroblast cells. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaCas4 nuclease protein structure
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This wreath represents the molecular structure of a protein, Cas4, which is part of a system, known as CRISPR, that bacteria use to protect themselves against viral invaders. Fred Dyda, NIDDK View MediaRNA strand
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Ribonucleic acid (RNA) has a sugar-phosphate backbone and the bases adenine (A), cytosine (C), guanine (G), and uracil (U). Crabtree + Company View MediaTrp_RS - tryptophanyl tRNA-synthetase family of enzymes
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This image represents the structure of TrpRS, a novel member of the tryptophanyl tRNA-synthetase family of enzymes. View MediaNucleosome
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Like a strand of white pearls, DNA wraps around an assembly of special proteins called histones (colored) to form the nucleosome, a structure responsible for regulating genes and condensing DNA strand Karolin Luger, Colorado State University View Media