Image and Video Gallery

This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Cell division phases in Xenopus frog cells

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These images show three stages of cell division in Xenopus XL177 cells, which are derived from tadpole epithelial cells. They are (from top): metaphase, anaphase and telophase. Claire Walczak, who took them while working as a postdoc in the laboratory of Timothy Mitchison View Media

Haplotypes

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Haplotypes are combinations of gene variants that are likely to be inherited together within the same chromosomal region. Crabtree + Company View Media

From DNA to Protein (labeled)

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The genetic code in DNA is transcribed into RNA, which is translated into proteins with specific sequences. Crabtree + Company View Media

Lily mitosis 07

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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media

GFP sperm

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Fruit fly sperm cells glow bright green when they express the gene for green fluorescent protein (GFP). View Media

Protein formation

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Proteins are 3D structures made up of smaller units. DNA is transcribed to RNA, which in turn is translated into amino acids. NIGMS, with the folded protein illustration adapted from Jane Richardson, Duke University Medical Center View Media

Telomeres on outer edge of nucleus during cell division

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New research shows telomeres moving to the outer edge of the nucleus after cell division, suggesting these caps that protect chromosomes also may play a role in organizing DNA. Laure Crabbe, Jamie Kasuboski and James Fitzpatrick, Salk Institute for Biological Studies View Media

Haplotypes (with labels)

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Haplotypes are combinations of gene variants that are likely to be inherited together within the same chromosomal region. Crabtree + Company View Media

Cross section of a Drosophila melanogaster pupa

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This photograph shows a magnified view of a Drosophila melanogaster pupa in cross section. Compare this normal pupa to one that lacks an important receptor, shown in image 2759. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View Media

Lily mitosis 05

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Central dogma, illustrated (with labels)

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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View Media

Gene silencing

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Pretty in pink, the enzyme histone deacetylase (HDA6) stands out against a background of blue-tinted DNA in the nucleus of an Arabidopsis plant cell. Olga Pontes and Craig Pikaard, Washington University View Media

Endoplasmic reticulum abnormalities

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Human cells with the gene that codes for the protein FIT2 deleted. Green indicates an endoplasmic reticulum (ER) resident protein. Michel Becuwe, Harvard University. View Media

Cas4 nuclease protein structure

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This wreath represents the molecular structure of a protein, Cas4, which is part of a system, known as CRISPR, that bacteria use to protect themselves against viral invaders. Fred Dyda, NIDDK View Media

Painted chromosomes

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Like a paint-by-numbers picture, painted probes tint individual human chromosomes by targeting specific DNA sequences. Beth A. Sullivan, Duke University View Media

RNA Polymerase II

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NIGMS-funded researchers led by Roger Kornberg solved the structure of RNA polymerase II. David Bushnell, Ken Westover and Roger Kornberg, Stanford University View Media

Fruit fly ovary

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A fruit fly ovary, shown here, contains as many as 20 eggs. Fruit flies are not merely tiny insects that buzz around overripe fruit—they are a venerable scientific tool. Denise Montell, Johns Hopkins University and University of California, Santa Barbara View Media

Mature, flowering Arabidopsis

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This is an adult flowering Arabidopsis thaliana plant with the inbred designation L-er. Arabidopsis is the most widely used model organism for researchers who study plant genetics. Jeff Dangl, University of North Carolina, Chapel Hill View Media

Histones in chromatin (with labels)

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Histone proteins loop together with double-stranded DNA to form a structure that resembles beads on a string. Crabtree + Company View Media

A dynamic model of the DNA helicase protein complex

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This short video shows a model of the DNA helicase in yeast. This DNA helicase has 11 proteins that work together to unwind DNA during the process of copying it, called DNA replication. Huilin Li, Stony Brook University View Media

Automated Worm Sorter - 4

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Georgia Tech associate professor Hang Lu holds a microfluidic chip that is part of a system that uses artificial intelligence and cutting-edge image processing to automatically examine large number of Georgia Tech/Gary Meek View Media

Alternative splicing

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Arranging exons in different patterns, called alternative splicing, enables cells to make different proteins from a single gene. Crabtree + Company View Media

Planting roots

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At the root tips of the mustard plant Arabidopsis thaliana (red), two proteins work together to control the uptake of water and nutrients. Philip Benfey, Duke University View Media

Bottles of warfarin

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In 2007, the FDA modified warfarin's label to indicate that genetic makeup may affect patient response to the drug. The widely used blood thinner is sold under the brand name Coumadin®. Alisa Machalek, NIGMS/NIH View Media

Recombinant DNA (with labels)

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To splice a human gene (in this case, the one for insulin) into a plasmid, scientists take the plasmid out of an E. Crabtree + Company View Media

Nucleotides make up DNA (with labels)

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DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule, and the sugar molecule deoxyribose. Crabtree + Company View Media

HIV enzyme

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These images model the molecular structures of three enzymes with critical roles in the life cycle of the human immunodeficiency virus (HIV). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Induced stem cells from adult skin 02

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These cells are induced stem cells made from human adult skin cells that were genetically reprogrammed to mimic embryonic stem cells. James Thomson, University of Wisconsin-Madison View Media

Retroviruses as fossils

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DNA doesn't leave a fossil record in stone, the way bones do. Instead, the DNA code itself holds the best evidence for organisms' genetic history. Emily Harrington, science illustrator View Media

Dividing cell in metaphase

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This image of a mammalian epithelial cell, captured in metaphase, was the winning image in the high- and super-resolution microscopy category of the 2012 GE Healthcare Life Sciences Cell Imaging Compe Jane Stout in the laboratory of Claire Walczak, Indiana University, GE Healthcare 2012 Cell Imaging Competition View Media

RSV-Infected Cell

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Viral RNA (red) in an RSV-infected cell. Eric Alonas and Philip Santangelo, Georgia Institute of Technology and Emory University View Media

Lily mitosis 09

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Genetic mosaicism in fruit flies

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Fat tissue from the abdomen of a genetically mosaic adult fruit fly. Genetic mosaicism means that the fly has cells with different genotypes even though it formed from a single zygote. Akhila Rajan, Fred Hutchinson Cancer Center View Media

Symmetrically and asymmetrically elongating cells

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Merged fluorescent images of symmetrically (left) or asymmetrically (right) elongating HeLa cells at the end of early anaphase (magenta) and late anaphase (green). Tomomi Kiyomitsu and Iain M. Cheeseman, Whitehead Institute for Biomedical Research View Media

Fruit fly ovaries

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Fruit fly (Drosophila melanogaster) ovaries with DNA shown in magenta and actin filaments shown in light blue. This image was captured using a confocal laser scanning microscope.
Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media

Mitotic cell awaits chromosome alignment

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During mitosis, spindle microtubules (red) attach to chromosome pairs (blue), directing them to the spindle equator. View Media

Lily mitosis 04

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CRISPR illustration

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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media

Dicer generates microRNAs

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The enzyme Dicer generates microRNAs by chopping larger RNA molecules into tiny Velcro^®-like pieces. MicroRNAs stick to mRNA molecules and prevent the mRNAs from being made into proteins. Crabtree + Company View Media

Life of an AIDS virus (with labels and stages)

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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View Media

Disease-resistant Arabidopsis leaf

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This is a magnified view of an Arabidopsis thaliana leaf a few days after being exposed to the pathogen Hyaloperonospora arabidopsidis. Jeff Dangl, University of North Carolina, Chapel Hill View Media

Meiosis illustration (with labels)

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Meiosis is the process whereby a cell reduces its chromosomes from diploid to haploid in creating eggs or sperm. Crabtree + Company View Media

Sponge

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Many of today's medicines come from products found in nature, such as this sponge found off the coast of Palau in the Pacific Ocean. Phil Baran, Scripps Research Institute View Media

Lily mitosis 10

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Histone deacetylases

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The human genome contains much of the information needed for every cell in the body to function. However, different types of cells often need different types of information. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Culex quinquefasciatus mosquito larva

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A mosquito larva with genes edited by CRISPR. The red-orange glow is a fluorescent protein used to track the edits. Valentino Gantz, University of California, San Diego. View Media

Introduction to Genome Editing Using CRISPR/Cas9

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Genome editing using CRISPR/Cas9 is a rapidly expanding field of scientific research with emerging applications in disease treatment, medical therapeutics and bioenergy, just to name a few. Janet Iwasa View Media

Mosaicism in C. elegans (White Background)

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In the worm C. elegans, double-stranded RNA made in neurons can silence matching genes in a variety of cell types through the transport of RNA between cells. Snusha Ravikumar, Ph.D., University of Maryland, College Park, and Antony M. Jose, Ph.D., University of Maryland, College Park View Media

Pulsating response to stress in bacteria

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By attaching fluorescent proteins to the genetic circuit responsible for B. subtilis's stress response, researchers can observe the cells' pulses as green flashes. Michael Elowitz, Caltech University View Media

Zebrafish larva

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You are face to face with a 6-day-old zebrafish larva. What look like eyes will become nostrils, and the bulges on either side will become eyes. Oscar Ruiz and George Eisenhoffer, University of Texas MD Anderson Cancer Center, Houston View Media

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