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Nucleotides make up DNA

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DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule, and the sugar molecule deoxyribose. Crabtree + Company View Media

Los ritmos circadianos y el núcleo supraquiasmático

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Los ritmos circadianos son cambios físicos, mentales y de comportamiento que siguen un ciclo de 24 horas. NIGMS View Media

Arabidopsis Thaliana: Flowers Spring to Life

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This image capture shows how a single gene, STM, plays a starring role in plant development. Nathanaёl Prunet NIH Support: National Institute of General Medical Sciences View Media

Lily mitosis 08

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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media

Telomeres

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The 46 human chromosomes are shown in blue, with the telomeres appearing as white pinpoints. Hesed Padilla-Nash and Thomas Ried, the National Cancer Institute, a part of NIH View Media

Microscopy image of bird-and-flower DNA origami

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An atomic force microscopy image shows DNA folded into an intricate, computer-designed structure. Hao Yan, Arizona State University View Media

Xenopus laevis embryos

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Xenopus laevis, the African clawed frog, has long been used as a model organism for studying embryonic development. The frog embryo on the left lacks the developmental factor Sizzled. Michael Klymkowsky, University of Colorado, Boulder View Media

Induced stem cells from adult skin 01

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These cells are induced stem cells made from human adult skin cells that were genetically reprogrammed to mimic embryonic stem cells. James Thomson, University of Wisconsin-Madison View Media

Lily mitosis 12

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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media

Fruit fly ovary

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A fruit fly ovary, shown here, contains as many as 20 eggs. Fruit flies are not merely tiny insects that buzz around overripe fruit—they are a venerable scientific tool. Denise Montell, Johns Hopkins University and University of California, Santa Barbara View Media

Katanin protein regulates anaphase

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The microtubule severing protein, katanin, localizes to chromosomes and regulates anaphase A in mitosis. David Sharp, Albert Einstein College of Medicine View Media

Telomeres on outer edge of nucleus during cell division

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New research shows telomeres moving to the outer edge of the nucleus after cell division, suggesting these caps that protect chromosomes also may play a role in organizing DNA. Laure Crabbe, Jamie Kasuboski and James Fitzpatrick, Salk Institute for Biological Studies View Media

Brain showing hallmarks of Alzheimer's disease

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Along with blood vessels (red) and nerve cells (green), this mouse brain shows abnormal protein clumps known as plaques (blue). Alvin Gogineni, Genentech View Media

CRISPR Illustration Frame 3

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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media

Central dogma, illustrated (with labels)

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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View Media

Life of an AIDS virus (with labels and stages)

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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View Media

RNA Polymerase II

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NIGMS-funded researchers led by Roger Kornberg solved the structure of RNA polymerase II. David Bushnell, Ken Westover and Roger Kornberg, Stanford University View Media

Nucleolus subcompartments spontaneously self-assemble 1

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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media

Developing zebrafish fin

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Originally from the waters of India, Nepal, and neighboring countries, zebrafish can now be found swimming in science labs (and home aquariums) throughout the world. Jessica Plavicki View Media

Pollen grains: male germ cells in plants and a cause of seasonal allergies

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Those of us who get sneezy and itchy-eyed every spring or fall may have pollen grains, like those shown here, to blame. Edna, Gil, and Amit Cukierman, Fox Chase Cancer Center, Philadelphia, Pa. View Media

Haplotypes

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Haplotypes are combinations of gene variants that are likely to be inherited together within the same chromosomal region. Crabtree + Company View Media

Symmetrically and asymmetrically elongating cells

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Merged fluorescent images of symmetrically (left) or asymmetrically (right) elongating HeLa cells at the end of early anaphase (magenta) and late anaphase (green). Tomomi Kiyomitsu and Iain M. Cheeseman, Whitehead Institute for Biomedical Research View Media

Automated Worm Sorter - 4

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Georgia Tech associate professor Hang Lu holds a microfluidic chip that is part of a system that uses artificial intelligence and cutting-edge image processing to automatically examine large number of Georgia Tech/Gary Meek View Media

Host infection stimulates antibiotic resistance

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This illustration shows pathogenic bacteria behave like a Trojan horse: switching from antibiotic susceptibility to resistance during infection. View Media

DNA replication origin recognition complex (ORC)

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A study published in March 2012 used cryo-electron microscopy to determine the structure of the DNA replication origin recognition complex (ORC), a semi-circular, protein complex (yellow) that recogni Huilin Li, Brookhaven National Laboratory View Media

Protein formation

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Proteins are 3D structures made up of smaller units. DNA is transcribed to RNA, which in turn is translated into amino acids. NIGMS, with the folded protein illustration adapted from Jane Richardson, Duke University Medical Center View Media

Life of an AIDS virus (with labels)

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HIV is a retrovirus, a type of virus that carries its genetic material not as DNA but as RNA. Crabtree + Company View Media

Zebrafish embryo

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Just 22 hours after fertilization, this zebrafish embryo is already taking shape. By 36 hours, all of the major organs will have started to form. Philipp Keller, Bill Lemon, Yinan Wan, and Kristin Branson, Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, Va. View Media

Cas9 protein involved in the CRISPR gene-editing technology

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In the gene-editing tool CRISPR, a small strand of RNA identifies a specific chunk of DNA. Janet Iwasa View Media

Painted chromosomes

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Like a paint-by-numbers picture, painted probes tint individual human chromosomes by targeting specific DNA sequences. Beth A. Sullivan, Duke University View Media

Dolly the sheep

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Scientists in Scotland were the first to clone an animal, this sheep named Dolly. She later gave birth to Bonnie, the lamb next to her. View Media

RNA interference

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RNA interference or RNAi is a gene-silencing process in which double-stranded RNAs trigger the destruction of specific RNAs. Crabtree + Company View Media

RNA strand (with labels)

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Ribonucleic acid (RNA) has a sugar-phosphate backbone and the bases adenine (A), cytosine (C), guanine (G), and uracil (U). Featured in The New Genetics. Crabtree + Company View Media

Chromosome fiber 01

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This microscopic image shows a chromatin fiber--a DNA molecule bound to naturally occurring proteins. Marc Green and Susan Forsburg, University of Southern California View Media

Highlighted cells

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The cytoskeleton (green) and DNA (purple) are highlighed in these cells by immunofluorescence. Torsten Wittmann, Scripps Research Institute View Media

Induced stem cells from adult skin 03

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The human skin cells pictured contain genetic modifications that make them pluripotent, essentially equivalent to embryonic stem cells. James Thomson, University of Wisconsin-Madison View Media

RSV-Infected Cell

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Viral RNA (red) in an RSV-infected cell. Eric Alonas and Philip Santangelo, Georgia Institute of Technology and Emory University View Media

Dicer generates microRNAs

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The enzyme Dicer generates microRNAs by chopping larger RNA molecules into tiny Velcro®-like pieces. MicroRNAs stick to mRNA molecules and prevent the mRNAs from being made into proteins. Crabtree + Company View Media

Circadian rhythms and the SCN

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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. NIGMS View Media

Genetic mosaicism in fruit flies

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Fat tissue from the abdomen of a genetically mosaic adult fruit fly. Genetic mosaicism means that the fly has cells with different genotypes even though it formed from a single zygote. Akhila Rajan, Fred Hutchinson Cancer Center View Media

Isolated Planarian Pharynx

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The feeding tube, or pharynx, of a planarian worm with cilia shown in red and muscle fibers shown in green View Media

Central dogma, illustrated

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DNA encodes RNA, which encodes protein. DNA is transcribed to make messenger RNA (mRNA). The mRNA sequence (dark red strand) is complementary to the DNA sequence (blue strand). Crabtree + Company View Media

Cross section of a Drosophila melanogaster pupa lacking Draper

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In the absence of the engulfment receptor Draper, salivary gland cells (light blue) persist in the thorax of a developing Drosophila melanogaster pupa. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View Media

Nucleotides make up DNA (with labels)

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DNA consists of two long, twisted chains made up of nucleotides. Each nucleotide contains one base, one phosphate molecule, and the sugar molecule deoxyribose. Crabtree + Company View Media

Gene silencing

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Pretty in pink, the enzyme histone deacetylase (HDA6) stands out against a background of blue-tinted DNA in the nucleus of an Arabidopsis plant cell. Olga Pontes and Craig Pikaard, Washington University View Media

From DNA to Protein (labeled)

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The genetic code in DNA is transcribed into RNA, which is translated into proteins with specific sequences. Crabtree + Company View Media

Fruit fly ovary_2

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A fruit fly ovary, shown here, contains as many as 20 eggs. Fruit flies are not merely tiny insects that buzz around overripe fruit--they are a venerable scientific tool. Denise Montell, University of California, Santa Barbara View Media

Circadian rhythm (with labels)

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The human body keeps time with a master clock called the suprachiasmatic nucleus or SCN. Crabtree + Company View Media

Early development in Arabidopsis

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Early on, this Arabidopsis plant embryo picks sides: While one end will form the shoot, the other will take root underground. Zachery R. Smith, Jeff Long lab at the Salk Institute for Biological Studies View Media

GFP sperm

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Fruit fly sperm cells glow bright green when they express the gene for green fluorescent protein (GFP). View Media