Image and Video Gallery

This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Cryo-electron microscopy revealing the "wasabi receptor"

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The TRPA1 protein is responsible for the burn you feel when you taste a bite of sushi topped with wasabi. Jean-Paul Armache, UCSF View Media

VDAC-1 (1)

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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media

Flower-forming cells in a small plant related to cabbage (Arabidopsis)

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In plants, as in animals, stem cells can transform into a variety of different cell types. The stem cells at the growing tip of this Arabidopsis plant will soon become flowers. Arun Sampathkumar and Elliot Meyerowitz, California Institute of Technology View Media

PanC from M. tuberculosis

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Model of an enzyme, PanC, that is involved in the last step of vitamin B5 biosynthesis in Mycobacterium tuberculosis. PanC is essential for the growth of M. Mycobacterium Tuberculosis Center, PSI View Media

Enzymes convert subtrates into products

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Enzymes convert substrates into products very quickly. See image 2522 for a labeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Protein folding video

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Proteins are long chains of amino acids. Each protein has a unique amino acid sequence. It is still a mystery how a protein folds into the proper shape based on its sequence. Theoretical and Computational Biophysics Group View Media

Chemokine CXCR4 receptor

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The receptor is shown bound to a small molecule peptide called CVX15. Raymond Stevens, The Scripps Research Institute View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 2

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Nucleosome

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Like a strand of white pearls, DNA wraps around an assembly of special proteins called histones (colored) to form the nucleosome, a structure responsible for regulating genes and condensing DNA strand Karolin Luger, Colorado State University View Media

Beaded bacteriophage

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This sculpture made of purple and clear glass beads depicts bacteriophage Phi174, a virus that infects bacteria. It rests on a surface that portrays an adaptive landscape, a conceptual visualization. Holly Wichman, University of Idaho. (Surface by A. Johnston; photo by J. Palmersheim) View Media

Serum albumin structure 3

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Serum albumin (SA) is the most abundant protein in the blood plasma of mammals. SA has a characteristic heart-shape structure and is a highly versatile protein. Wladek Minor, University of Virginia View Media

Molecular interactions

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This network map shows molecular interactions (yellow) associated with a congenital condition that causes heart arrhythmias and the targets for drugs that alter these interactions (red and blue). Ravi Iyengar, Mount Sinai School of Medicine View Media

RNA Polymerase II

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NIGMS-funded researchers led by Roger Kornberg solved the structure of RNA polymerase II. David Bushnell, Ken Westover and Roger Kornberg, Stanford University View Media

Actin filaments bundled around the dynamin helical polymer

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Multiple actin filaments (magenta) are organized around a dynamin helical polymer (rainbow colored) in this model derived from cryo-electron tomography. Elizabeth Chen, University of Texas Southwestern Medical Center. View Media

RNA polymerase

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RNA polymerase (purple) is a complex enzyme at the heart of transcription. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Nuclear Lamina – Three Views

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Three views of the entire nuclear lamina of a HeLa cell produced by tilted light sheet 3D single-molecule super-resolution imaging using a platform termed TILT3D. Anna-Karin Gustavsson, Ph.D. View Media

Beta 2-adrenergic receptor

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The receptor is shown bound to a partial inverse agonist, carazolol. Raymond Stevens, The Scripps Research Institute View Media

Zika virus

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Zika virus is shown in cross section at center left. On the outside, it includes envelope protein (red) and membrane protein (magenta) embedded in a lipid membrane (light purple). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

RNA folding in action

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An RNA molecule dynamically refolds itself as it is being synthesized. When the RNA is short, it ties itself into a “knot” (dark purple). Julius Lucks, Northwestern University View Media

Enzyme reaction

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Enzymes speed up chemical reactions by reducing the amount of energy needed for the reactions. NIGMS View Media

Human endoplasmic reticulum membrane protein complex

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A 3D model of the human endoplasmic reticulum membrane protein complex (EMC) that identifies its nine essential subunits. Rebecca Voorhees, California Institute of Technology. View Media

PanB from M. tuberculosis (2)

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Model of an enzyme, PanB, from Mycobacterium tuberculosis, the bacterium that causes most cases of tuberculosis. This enzyme is an attractive drug target. Mycobacterium Tuberculosis Center, PSI-1 View Media

Himastatin and bacteria

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A model of the molecule himastatin overlaid on an image of Bacillus subtilis bacteria. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

SARS-CoV-2 nucleocapsid dimer

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In SARS-CoV-2, the virus that causes COVID-19, nucleocapsid is a complex molecule with many functional parts. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Hsp33 figure 2

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Featured in the March 15, 2012 issue of Biomedical Beat. Related to Hsp33 Figure 1, image 3354. Ursula Jakob and Dana Reichmann, University of Michigan View Media

G switch

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The G switch allows our bodies to respond rapidly to hormones. See images 2537 and 2538 for labeled versions of this image. Crabtree + Company View Media

Trajectories of labeled cell receptors

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Trajectories of single molecule labeled cell surface receptors. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View Media

3-D Architecture of a Synapse

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This image shows the structure of a synapse, or junction between two nerve cells in three dimensions. From the brain of a mouse. Anton Maximov, The Scripps Research Institute, La Jolla, CA View Media

Bovine milk alpha-lactalbumin (2)

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Crystals of bovine milk alpha-lactalbumin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Transient receptor potential channel TRPV5

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A 3D reconstruction of a transient receptor potential channel called TRPV5 that was created based on cryo-electron microscopy images. Vera Moiseenkova-Bell, University of Pennsylvania. View Media

Tiny strands of tubulin, a protein in a cell's skeleton

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Just as our bodies rely on bones for structural support, our cells rely on a cellular skeleton. Pakorn Kanchanawong, National University of Singapore and National Heart, Lung, and Blood Institute, National Institutes of Health; and Clare Waterman, National Heart, Lung, and Blood Institute, National Institutes of Health View Media

Disease-susceptible Arabidopsis leaf

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This is a magnified view of an Arabidopsis thaliana leaf after several days of infection with the pathogen Hyaloperonospora arabidopsidis. Jeff Dangl, University of North Carolina, Chapel Hill View Media

Bacteriophage P22 capsid

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Cryo-electron microscopy (cryo-EM) has the power to capture details of proteins and other small biological structures at the molecular level. This image shows proteins in the capsid, or outer co Dr. Wah Chiu, Baylor College of Medicine View Media

Ribonuclease P structure

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Ribbon diagram showing the structure of Ribonuclease P with tRNA. PDB entry 3Q1Q, molecular modeling by Fred Friedman, NIGMS View Media

Antitoxin GhoS (Illustration 1)

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Structure of the bacterial antitoxin protein GhoS. GhoS inhibits the production of a bacterial toxin, GhoT, which can contribute to antibiotic resistance. Rebecca Page and Wolfgang Peti, Brown University and Thomas K. Wood, Pennsylvania State University View Media

Intasome

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Salk researchers captured the structure of a protein complex called an intasome (center) that lets viruses similar to HIV establish permanent infection in their hosts. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media

ARTS triggers apoptosis

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Cell showing overproduction of the ARTS protein (red). ARTS triggers apoptosis, as shown by the activation of caspase-3 (green) a key tool in the cell's destruction. The nucleus is shown in blue. Hermann Steller, Rockefeller University View Media

Magnesium transporter protein from E. faecalis

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Structure of a magnesium transporter protein from an antibiotic-resistant bacterium (Enterococcus faecalis) found in the human gut. New York Structural GenomiX Consortium View Media

Atomic Structure of Poppy Enzyme

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The atomic structure of the morphine biosynthetic enzyme salutaridine reductase bound to the cofactor NADPH. The substrate salutaridine is shown entering the active site. Judy Coyle, Donald Danforth Plant Science Center View Media

Structure of a key antigen protein involved with Hepatitis C Virus infection

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A three-dimensional representation of the structure of E2, a key antigen protein involved with hepatitis C virus infection. Mansun Law Associate Professor Department of Immunolgy and Microbial Science The Scripps Research Institute View Media

Early life of a protein

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This illustration represents the early life of a protein—specifically, apomyoglobin—as it is synthesized by a ribosome and emerges from the ribosomal tunnel, which contains the newly formed protein's Silvia Cavagnero, University of Wisconsin, Madison View Media

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