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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
RNase A (1)
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A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaRespiratory droplet
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This painting shows a cross section of a small respiratory droplet, like the ones that are thought to transmit SARS-CoV-2, the virus that causes COVID-19. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaHIV Capsid
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This image is a computer-generated model of the approximately 4.2 million atoms of the HIV capsid, the shell that contains the virus' genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View MediaZebrafish embryo
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A zebrafish embryo showing its natural colors. Zebrafish have see-through eggs and embryos, making them ideal research organisms for studying the earliest stages of development. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaSeeing signaling protein activation in cells 04
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Cdc42, a member of the Rho family of small guanosine triphosphatase (GTPase) proteins, regulates multiple cell functions, including motility, proliferation, apoptosis, and cell morphology. Klaus Hahn, University of North Carolina, Chapel Hill Medical School View MediaRNA folding in action
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An RNA molecule dynamically refolds itself as it is being synthesized. When the RNA is short, it ties itself into a “knot” (dark purple). Julius Lucks, Northwestern University View MediaDynamin Fission
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Time lapse series shows short dynamin assemblies (not visible) constricting a lipid tube to make a "beads on a string" appearance, then cutting off one of the beads i.e., catalyzing membrane fission). Ramachandran, Pucadyil et al. , The Scripps Research Institute View MediaMicrotubule dynamics in real time
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Cytoplasmic linker protein (CLIP)-170 is a microtubule plus-end-tracking protein that regulates microtubule dynamics and links microtubule ends to different intracellular structures. Gary Borisy, Marine Biology Laboratory View MediaHsp33 figure 1
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Featured in the March 15, 2012 issue of Biomedical Beat. Related to Hsp33 Figure 2, image 3355. Ursula Jakob and Dana Reichmann, University of Michigan View MediaSphingolipid S1P1 receptor
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The receptor is shown bound to an antagonist, ML056. Raymond Stevens, The Scripps Research Institute View MediaClathrin-mediated endocytosis
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Endocytosis is the process by which cells are able to take up membrane and extracellular materials through the formation of a small intracellular bubble, called a vesicle. Janet Iwasa, University of Utah View MediaPartial Model of a Cilium’s Doublet Microtubule
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Cilia (cilium in singular) are complex molecular machines found on many of our cells. Brown Lab, Harvard Medical School and Veronica Falconieri Hays. View MediaCatalase diversity
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Catalases are some of the most efficient enzymes found in cells. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaCells keep their shape with actin filaments and microtubules
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This image shows a normal fibroblast, a type of cell that is common in connective tissue and frequently studied in research labs. James J. Faust and David G. Capco, Arizona State University View MediaVDAC video 03
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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaMolecules blocking Huntington's protein production
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The molecules that glow blue in these cultured cells prevent the expression of the mutant proteins that cause Huntington's disease. Jiaxin Hu, David W. Dodd and Robert H. E. Hudson, UT Southwestern Medical Center View MediaX-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 7
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View MediaCytonemes in developing fruit fly cells
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Scientists have long known that multicellular organisms use biological molecules produced by one cell and sensed by another to transmit messages that, for instance, guide proper development of organs Sougata Roy, University of California, San Francisco View MediaKluyveromyces polysporus Argonaute bound to guide RNA
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A segment of siRNA, shown in red, guides a "slicer" protein called Argonaute (multi-colored twists and corkscrews) to the target RNA molecules. Kotaro Nakanishi and David Weinberg, Massachusetts Institute of Technology View MediaAntitoxin GhoS (Illustration 2)
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Structure of the bacterial antitoxin protein GhoS. GhoS inhibits the production of a bacterial toxin, GhoT, which can contribute to antibiotic resistance. Rebecca Page and Wolfgang Peti, Brown University and Thomas K. Wood, Pennsylvania State University View MediaBacteria working to eat
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Gram-negative bacteria perform molecular acrobatics just to eat. Because they're encased by two membranes, they must haul nutrients across both. Emad Tajkhorshid, University of Illinois at Urbana-Champaign View MediaRotavirus structure
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This image shows a computer-generated, three-dimensional map of the rotavirus structure. This virus infects humans and other animals and causes severe diarrhea in infants and young children. Bridget Carragher, The Scripps Research Institute, La Jolla, CA View MediaProtective membrane and membrane proteins of the dengue virus visualized with cryo-EM
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Dengue virus is a mosquito-borne illness that infects millions of people in the tropics and subtropics each year. Like many viruses, dengue is enclosed by a protective membrane. Hong Zhou, UCLA View MediaProtein kinases as cancer chemotherapy targets
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Protein kinases—enzymes that add phosphate groups to molecules—are cancer chemotherapy targets because they play significant roles in almost all aspects of cell function, are tightly regulated, and co Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaVDAC-1 (2)
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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaProtein map
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Network diagram showing a map of protein-protein interactions in a yeast (Saccharomyces cerevisiae) cell. This cluster includes 78 percent of the proteins in the yeast proteome. Hawoong Jeong, KAIST, Korea View MediaElectrostatic map of human spermine synthase
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From PDB entry 3c6k, Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine. Emil Alexov, Clemson University View MediaBeaded bacteriophage
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This sculpture made of purple and clear glass beads depicts bacteriophage Phi174, a virus that infects bacteria. It rests on a surface that portrays an adaptive landscape, a conceptual visualization. Holly Wichman, University of Idaho. (Surface by A. Johnston; photo by J. Palmersheim) View MediaShiga toxin being sorted inside a cell
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Shiga toxin (green) is sorted from the endosome into membrane tubules (red), which then pinch off and move to the Golgi apparatus. Somshuvra Mukhopadhyay, The University of Texas at Austin, and Adam D. Linstedt, Carnegie Mellon University View MediaMap of protein structures 02
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A global "map of the protein structure universe" indicating the positions of specific proteins. Berkeley Structural Genomics Center, PSI View MediaBeta2-adrenergic receptor protein
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Crystal structure of the beta2-adrenergic receptor protein. The Stevens Laboratory, The Scripps Research Institute View MediaPig trypsin (3)
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Crystals of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaX-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View MediaJack bean concanavalin A
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Crystals of jack bean concanavalin A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaMaster clock of the mouse brain
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An image of the area of the mouse brain that serves as the 'master clock,' which houses the brain's time-keeping neurons. The nuclei of the clock cells are shown in blue. Erik Herzog, Washington University in St. Louis View MediaZ rings in bacterial division
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Lab-made liposomes contract where Z rings have gathered together and the constriction forces are greatest (arrows). Masaki Osawa, Duke University View MediaFruit fly embryo
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Cells in an early-stage fruit fly embryo, showing the DIAP1 protein (pink), an inhibitor of apoptosis. Hermann Steller, Rockefeller University View MediaCryo-EM reveals how the HIV capsid attaches to a human protein to evade immune detection
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The illustration shows the capsid of human immunodeficiency virus (HIV) whose molecular features were resolved with cryo-electron microscopy (cryo-EM). Juan R. Perilla, University of Illinois at Urbana-Champaign View MediaVDAC-1 (3)
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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaVDAC video 02
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This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaZika virus
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Zika virus is shown in cross section at center left. On the outside, it includes envelope protein (red) and membrane protein (magenta) embedded in a lipid membrane (light purple). Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaBence Jones protein MLE
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A crystal of Bence Jones protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaMeasles virus proteins
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A cross section of the measles virus in which six proteins (enlarged on the outside of the virus) work together to infect cells. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View MediaKatanin protein regulates anaphase
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The microtubule severing protein, katanin, localizes to chromosomes and regulates anaphase A in mitosis. David Sharp, Albert Einstein College of Medicine View MediaDNA replication origin recognition complex (ORC)
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A study published in March 2012 used cryo-electron microscopy to determine the structure of the DNA replication origin recognition complex (ORC), a semi-circular, protein complex (yellow) that recogni Huilin Li, Brookhaven National Laboratory View MediaAbnormal, spiky fibroblast
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This is a fibroblast, a connective tissue cell that plays an important role in wound healing. Normal fibroblasts have smooth edges. Praveen Suraneni, Stowers Institute for Medical Research, Kansas City, Mo. View MediaVDAC-1 (4)
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The structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View MediaDynamic cryo-EM model of the human transcription preinitiation complex
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Gene transcription is a process by which information encoded in DNA is transcribed into RNA. Eva Nogales, Berkeley Lab View MediaStructure of heme, top view
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Molecular model of the struture of heme. Heme is a small, flat molecule with an iron ion (dark red) at its center. Rachel Kramer Green, RCSB Protein Data Bank View MediaHuman endoplasmic reticulum membrane protein complex
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A 3D model of the human endoplasmic reticulum membrane protein complex (EMC) that identifies its nine essential subunits. Rebecca Voorhees, California Institute of Technology. View Media