Image and Video Gallery

This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Hsp33 figure 1

3354

Featured in the March 15, 2012 issue of Biomedical Beat. Related to Hsp33 Figure 2, image 3355. Ursula Jakob and Dana Reichmann, University of Michigan View Media

Measles virus

6995

A cross section of the measles virus in which six proteins work together to infect cells. The measles virus is extremely infectious; 9 out of 10 people exposed will contract the disease. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Abnormal, spiky fibroblast

3613

This is a fibroblast, a connective tissue cell that plays an important role in wound healing. Normal fibroblasts have smooth edges. Praveen Suraneni, Stowers Institute for Medical Research, Kansas City, Mo. View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 7

3419

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

RNA Polymerase II

2484

NIGMS-funded researchers led by Roger Kornberg solved the structure of RNA polymerase II. David Bushnell, Ken Westover and Roger Kornberg, Stanford University View Media

Jack bean concanavalin A

2407

Crystals of jack bean concanavalin A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

tRNA splicing enzyme endonuclease in humans

2351

An NMR solution structure model of the transfer RNA splicing enzyme endonuclease in humans (subunit Sen15). This represents the first structure of a eukaryotic tRNA splicing endonuclease subunit. Center for Eukaryotic Structural Genomics, PSI View Media

H1 histamine receptor

3360

The receptor is shown bound to an inverse agonist, doxepin. Raymond Stevens, The Scripps Research Institute View Media

Disease-susceptible Arabidopsis leaf

2782

This is a magnified view of an Arabidopsis thaliana leaf after several days of infection with the pathogen Hyaloperonospora arabidopsidis. Jeff Dangl, University of North Carolina, Chapel Hill View Media

Z rings in bacterial division

2456

Lab-made liposomes contract where Z rings have gathered together and the constriction forces are greatest (arrows). Masaki Osawa, Duke University View Media

Thymidylate synthase complementing protein from Thermotoga maritime

2387

A model of thymidylate synthase complementing protein from Thermotoga maritime. Joint Center for Structural Genomics, PSI View Media

Histones in chromatin (with labels)

2561

Histone proteins loop together with double-stranded DNA to form a structure that resembles beads on a string. Crabtree + Company View Media

PanB from M. tuberculosis (2)

2382

Model of an enzyme, PanB, from Mycobacterium tuberculosis, the bacterium that causes most cases of tuberculosis. This enzyme is an attractive drug target. Mycobacterium Tuberculosis Center, PSI-1 View Media

Microtubule dynamics in real time

2784

Cytoplasmic linker protein (CLIP)-170 is a microtubule plus-end-tracking protein that regulates microtubule dynamics and links microtubule ends to different intracellular structures. Gary Borisy, Marine Biology Laboratory View Media

Histone deacetylases

7001

The human genome contains much of the information needed for every cell in the body to function. However, different types of cells often need different types of information. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Chang Shan

3483

For thousands of years, Chinese herbalists have treated malaria using Chang Shan, a root extract from a type of hydrangea that grows in Tibet and Nepal. Paul Schimmel Lab, Scripps Research Institute View Media

Proteasome

3451

This fruit fly spermatid recycles various molecules, including malformed or damaged proteins. Sigi Benjamin-Hong, Rockefeller University View Media

Molecular interactions

2743

This network map shows molecular interactions (yellow) associated with a congenital condition that causes heart arrhythmias and the targets for drugs that alter these interactions (red and blue). Ravi Iyengar, Mount Sinai School of Medicine View Media

Fungal lipase (2)

2411

Crystals of fungal lipase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Pig trypsin crystal

2403

A crystal of pig trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

DNase

2410

Crystals of DNase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

VDAC video 03

2572

This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media

Cellular aging

2578

A protein called tubulin (green) accumulates in the center of a nucleus (outlined in pink) from an aging cell. Maximiliano D'Angelo and Martin Hetzer, Salk Institute View Media

Sphingolipid S1P1 receptor

3362

The receptor is shown bound to an antagonist, ML056. Raymond Stevens, The Scripps Research Institute View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 3

3415

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

RNA folding in action

6625

An RNA molecule dynamically refolds itself as it is being synthesized. When the RNA is short, it ties itself into a “knot” (dark purple). Julius Lucks, Northwestern University View Media

Aminopeptidase N from N. meningitidis

2341

Model of the enzyme aminopeptidase N from the human pathogen Neisseria meningitidis, which can cause meningitis epidemics. Midwest Center for Structural Genomics, PSI View Media

Rabbit GPDA

2405

A crystal of rabbit GPDA protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

VDAC video 01

2570

This video shows the structure of the pore-forming protein VDAC-1 from humans. Gerhard Wagner, Harvard Medical School View Media

Stetten Lecture 2017poster image

5896

This image is featured on the poster for Dr. Rommie Amaro's 2017 Stetten Lecture. Dr. Rommie Amaro, University of California, San Diego View Media

3-D Architecture of a Synapse

5885

This image shows the structure of a synapse, or junction between two nerve cells in three dimensions. From the brain of a mouse. Anton Maximov, The Scripps Research Institute, La Jolla, CA View Media

Drosophila (fruit fly) myosin 1D motility assay

6562

Actin gliding powered by myosin 1D. Note the counterclockwise motion of the gliding actin filaments. Serapion Pyrpassopoulos and E. Michael Ostap, University of Pennsylvania View Media

Dimeric ferredoxin-like protein from an unidentified marine microbe

2340

This is the first structure of a protein derived from the metagenomic sequences collected during the Sorcerer II Global Ocean Sampling project. Joint Center for Structural Genomics View Media

Zebrafish embryo

6897

A zebrafish embryo showing its natural colors. Zebrafish have see-through eggs and embryos, making them ideal research organisms for studying the earliest stages of development. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Shiga toxin

6997

E. coli bacteria normally live harmlessly in our intestines, but some cause disease by making toxins. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Molecular view of glutamatergic synapse

6992

This illustration highlights spherical pre-synaptic vesicles that carry the neurotransmitter glutamate. Amy Wu and Christine Zardecki, RCSB Protein Data Bank. View Media

Movie of the 19S proteasome subunit processing a protein substrate

3764

The proteasome is a critical multiprotein complex in the cell that breaks down and recycles proteins that have become damaged or are no longer needed. Andreas Martin, HHMI View Media

Protein rv2844 from M. tuberculosis

2343

This crystal structure shows a conserved hypothetical protein from Mycobacterium tuberculosis. Only 12 other proteins share its sequence homology, and none has a known function. Integrated Center for Structure and Function Innovation View Media

PanC from M. tuberculosis

2383

Model of an enzyme, PanC, that is involved in the last step of vitamin B5 biosynthesis in Mycobacterium tuberculosis. PanC is essential for the growth of M. Mycobacterium Tuberculosis Center, PSI View Media

Cryo-EM reveals how the HIV capsid attaches to a human protein to evade immune detection

3755

The illustration shows the capsid of human immunodeficiency virus (HIV) whose molecular features were resolved with cryo-electron microscopy (cryo-EM). Juan R. Perilla, University of Illinois at Urbana-Champaign View Media

G switch

2536

The G switch allows our bodies to respond rapidly to hormones. See images 2537 and 2538 for labeled versions of this image. Crabtree + Company View Media

Oligoendopeptidase F from B. stearothermophilus

2373

Crystal structure of oligoendopeptidase F, a protein slicing enzyme from Bacillus stearothermophilus, a bacterium that can cause food products to spoil. Accelerated Technologies Center for Gene to 3D Structure/Midwest Center for Structural Genomics View Media

Isolated Planarian Pharynx

3593

The feeding tube, or pharynx, of a planarian worm with cilia shown in red and muscle fibers shown in green View Media

Nicotinic acid phosphoribosyltransferase

2355

Model of the enzyme nicotinic acid phosphoribosyltransferase. Berkeley Structural Genomics Center, PSI View Media

Kappa opioid receptor

3359

The receptor is shown bound to an antagonist, JDTic. Raymond Stevens, The Scripps Research Institute View Media

3D reconstruction of a tubular matrix in peripheral endoplasmic reticulum

5857

Detailed three-dimensional reconstruction of a tubular matrix in a thin section of the peripheral endoplasmic reticulum between the plasma membranes of the cell. Jennifer Lippincott-Schwartz, Howard Hughes Medical Institute Janelia Research Campus, Virginia View Media

Aldolase

6350

2.5Å resolution reconstruction of rabbit muscle aldolase collected on a FEI/Thermo Fisher Titan Krios with energy filter and image corrector. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media

Dense tubular matrices in the peripheral endoplasmic reticulum (ER) 2

5856

Three-dimensional reconstruction of a tubular matrix in a thin section of the peripheral endoplasmic reticulum between the plasma membranes of the cell. Jennifer Lippincott-Schwartz, Howard Hughes Medical Institute Janelia Research Campus, Virginia View Media

Optic nerve astrocytes

5852

Astrocytes in the cross section of a human optic nerve head Tom Deerinck and Keunyoung (“Christine”) Kim, NCMIR View Media

Fruit fly spermatids

3590

Developing spermatids (precursors of mature sperm cells) begin as small, round cells and mature into long-tailed, tadpole-shaped ones. Lacramioara Fabian, The Hospital for Sick Children, Toronto, Canada View Media

More Images...

View All Images