| Name |
Year |
Field |
Citation |
Announcement |
|---|
| Joachim Frank |
2017 |
Chemistry |
For developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution |
https://www.nih.gov/news-events/news-releases/nih-grantee-wins-2017-nobel-prize-chemistry |
|---|
| Jeffrey C. Hall, Michael Rosbash, & Michael W. Young |
2017 |
Physiology or Medicine |
For their discoveries of molecular mechanisms controlling the circadian rhythm |
https://www.nih.gov/news-events/news-releases/nih-grantees-win-2017-nobel-prize-physiology-or-medicine |
|---|
| Paul Modrich & Aziz Sancar |
2015 |
Chemistry |
For mechanistic studies of DNA repair |
http://www.nigms.nih.gov/News/Results/
pages/20151007.aspx |
|---|
| William E. Moerner |
2014 |
Chemistry |
For the development of super-resolved fluorescence microscopy |
http://www.nigms.nih.gov/News/Results/
pages/20141008.aspx |
|---|
| Martin Karplus, Michael Levitt & Arieh Warshel |
2013 |
Chemistry |
For the development of multiscale models for complex chemical systems |
http://www.nigms.nih.gov/News/Results/
pages/20131024 |
|---|
| James E. Rothman & Randy W. Schekman |
2013 |
Physiology
or
Medicine |
For their discoveries of machinery regulating vesicle traffic, a major transport system in our cells |
http://www.nigms.nih.gov/News/Results/
pages/20131024 |
|---|
| Brian K. Kobilka |
2012 |
Chemistry |
For studies of G-protein-coupled receptors |
http://www.nigms.nih.gov/News/Results/
pages/20121010.htm |
|---|
| Ei-ichi Negishi |
2010 |
Chemistry |
For palladium-catalyzed cross couplings in organic synthesis |
http://www.nigms.nih.gov/News/Results/
pages/nobelprize_101006.htm |
|---|
| Venkatraman Ramakrishnan, Thomas A. Steitz & Ada E. Yonath |
2009 |
Chemistry |
For studies of the structure and function of the ribosome |
http://www.nigms.nih.gov/News/Results/
pages/nobel_20091007a.htm |
|---|
| Elizabeth H. Blackburn, Carol W. Greider & Jack W. Szostak |
2009 |
Physiology
or
Medicine |
For the discovery of how chromosomes are protected by telomeres and the enzyme telomerase |
http://www.nigms.nih.gov/News/Results/
pages/nobel20091005.htm |
|---|
| Osamu Shimomura, Martin Chalfie & Roger Y. Tsien |
2008 |
Chemistry |
For the discovery and development of the green fluorescent protein, GFP |
http://www.nigms.nih.gov/News/Results/
pages/nobel_chemistry20081008.htm |
|---|
| Mario R. Capecchi & Oliver Smithies |
2007 |
Physiology
or
Medicine |
For the discovery of principles for introducing specific gene modifications in mice by the use of embryonic stem cells |
http://www.nigms.nih.gov/News/Results/
pages/10082007c.htm |
|---|
| Roger D. Kornberg |
2006 |
Chemistry |
For his studies of the molecular basis of eukaryotic transcription |
http://www.nigms.nih.gov/News/Results/
pages/10042006_nobel2.htm |
|---|
| Andrew Z. Fire & Craig C. Mello |
2006 |
Physiology
or
Medicine |
For the discovery of RNA interference—gene silencing by double-stranded RNA |
http://www.nigms.nih.gov/News/Nobels/
pages/10022006_nobel2.htm |
|---|
| Robert H. Grubbs & Richard R. Schrock |
2005 |
Chemistry |
For the development of the metathesis method in organic synthesis [a chemical reaction for making carbon-carbon bonds] |
https://nihrecord.nih.gov/newsletters/
2005/10_21_2005/story10.htm |
|---|
| Avram Hershko & Irwin Rose |
2004 |
Chemistry |
For the discovery of ubiquitin-mediated protein degradation |
http://www.nih.gov/news/pr/oct2004/od-06.htm |
|---|
| Paul C. Lauterbur |
2003 |
Physiology
or
Medicine |
For discoveries concerning magnetic resonance imaging |
http://www.nigms.nih.gov/News/Results/
pages/Nobel_Medicine_2003.htm |
|---|
| Roderick MacKinnon |
2003 |
Chemistry |
For discoveries concerning channels in cell membranes [specifically, for structural and mechanistic studies of ion channels] |
http://www.nigms.nih.gov/News/Results/
pages/Nobel_Chemistry_2003.htm |
|---|
| H. Robert Horvitz |
2002 |
Physiology
or
Medicine |
For discoveries concerning genetic regulation of organ development and programmed cell death |
https://www.nigms.nih.gov/News/Results/
Pages/NIHGranteeHRobertHorvitzWins.aspx |
|---|
| John B. Fenn |
2002 |
Chemistry |
For the development of methods for identification and structure analyses of biological macromolecules [specifically, for techniquesin mass spectrometry] |
http://www.nigms.nih.gov/News/Results/
pages/NIGMSGranteeJohnFennWins
NobelPrize.htm |
|---|
| Leland H. Hartwell |
2001 |
Physiology
or
Medicine |
For discoveries of key regulators of the cell cycle |
http://www.nigms.nih.gov/News/Results/
pages/NIHGranteeLelandHartwellWinsNobel
PrizeBreakthroughsUnderstanding.htm |
|---|
| K. Barry Sharpless |
2001 |
Chemistry |
For work on chirally catalyzed oxidation reactions [a technique to selectively control the outcome of chemical reactions] |
http://www.nigms.nih.gov/News/Results/
pages/NIGMSGranteeKBarrySharplessWins
NobelPrizeAdvances.htm |
|---|
| Eric R. Kandel |
2000 |
Physiology
or
Medicine |
For discoveries concerning signal transduction in the nervous system |
https://nihrecord.nih.gov/newsletters/
10_31_2000/story03.htm |
|---|
| Günter Blobel |
1999 |
Physiology
or
Medicine |
For the discovery that proteins have intrinsic signals that govern their transport and localization in the cell |
https://nihrecord.nih.gov/newsletters/
11_02_99/story04.htm |
|---|
| John A. Pople |
1998 |
Chemistry |
For development of computational methods in quantum chemistry |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1998/press.html  |
|---|
| Paul D. Boyer |
1997 |
Chemistry |
For elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP) |
https://nihrecord.nih.gov/newsletters/
11_04_97/story06.htm |
|---|
| Stanley B. Prusiner |
1997 |
Physiology
or
Medicine |
For discovery of prions—a new biological principle of infection |
https://nihrecord.nih.gov/newsletters/
11_04_97/story06.htm |
|---|
| Edward B. Lewis |
1995 |
Physiology
or
Medicine |
For discoveries concerning the genetic control of early embryonic development |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1995/press.html |
|---|
| George A. Olah |
1994 |
Chemistry |
For contributions to carbocation chemistry |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1994/press.html |
|---|
| Alfred G. Gilman |
1994 |
Physiology
or
Medicine |
For discovery of G-proteins and the role of these proteins in signal transduction in cells |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1994/press.html |
|---|
| Kary B. Mullis |
1993 |
Chemistry |
For contributions to the developments of methods within DNA- based chemistry [specifically, for his invention of the polymerasechain reaction (PCR) method] |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1993/press.html |
|---|
| Michael Smith |
1993 |
Chemistry |
For contributions to the development of methods within DNA-based chemistry [specifically, for his fundamental contributions to the establishment of oligonucleotide-based, site-directed mutagenesis and its development for protein studies] |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1993/press.html |
|---|
| Richard J. Roberts & Phillip A. Sharp |
1993 |
Physiology
or
Medicine |
For discoveries of split-genes |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1993/press.html |
|---|
| Edmond H. Fischer & Edwin G. Krebs |
1992 |
Physiology
or
Medicine |
For discoveries concerning reversible protein phosphorylation as a biological regulatory mechanism |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1992/press.html |
|---|
| Elias J. Corey |
1990 |
Chemistry |
For development of the theory and methodology of organic synthesis |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1990/press.html |
|---|
| Sidney Altman & Thomas R. Cech |
1989 |
Chemistry |
For discovery of catalytic properties of RNA |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1989/press.html |
|---|
| Donald J. Cram |
1987 |
Chemistry |
For development and use of molecules with structure-specific interactions of high selectivity |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1987/press.html |
|---|
| Stanley Cohen |
1986 |
Physiology
or
Medicine |
For discoveries of growth factors |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1986/press.html |
|---|
| Herbert A. Hauptman |
1985 |
Chemistry |
For outstanding achievements in the development of direct methods for the determination of crystal structures |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1985/press.html |
|---|
| Michael S. Brown & Joseph L. Goldstein |
1985 |
Physiology
or
Medicine |
For discoveries concerning the regulation of cholesterol metabolism |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1985/press.html |
|---|
| Henry Taube |
1983 |
Chemistry |
For work on the mechanisms of electron transfer reactions, especially in metal complexes |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1983/press.html |
|---|
| John R. Vane |
1982 |
Physiology
or
Medicine |
For discoveries concerning prostaglandins and related biologically active substances |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1982/press.html |
|---|
| Roald Hoffmann |
1981 |
Chemistry |
For theories, developed independently, concerning the course of chemical reactions |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1981/press.html |
|---|
| David H. Hubel |
1981 |
Physiology
or
Medicine |
For discoveries concerning information processing in the visual system |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1981/press.html |
|---|
| Paul Berg |
1980 |
Chemistry |
For fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1980/press.html |
|---|
| Walter Gilbert |
1980 |
Chemistry |
For contributions concerning the determination of base sequences in nucleic acids |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1980/press.html |
|---|
| Herbert C. Brown |
1979 |
Chemistry |
For development of the use of boron- and phosphorus-containing compounds, respectively, into important reagents in organic synthesis |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1979/press.html |
|---|
| Daniel Nathans & Hamilton O. Smith |
1978 |
Physiology
or
Medicine |
For the discovery of restriction enzymes and their application to problems of molecular genetics |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1978/press.html |
|---|
| Andrew V. Schally |
1977 |
Physiology
or
Medicine |
For discoveries concerning the peptide hormone production of the brain |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1977/press.html |
|---|
| William N. Lipscomb |
1976 |
Chemistry |
For studies on the structure of boranes illuminating problems of chemical bonding |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1976/press.html |
|---|
| Christian de Duve & George E. Palade |
1974 |
Physiology
or
Medicine |
For discoveries concerning the structural and functional organization of the cell |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1974/press.html |
|---|
| Stanford Moore & William H. Stein |
1972 |
Chemistry |
For contributions to the understanding of the connection between chemical structure and catalytic activity of the active center of the ribonuclease molecule |
http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1972/press.html |
|---|
| Earl W. Sutherland, Jr. |
1971 |
Physiology
or
Medicine |
For discoveries concerning the mechanisms of the action of hormones |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1971/press.html |
|---|
| Luis F. Leloir |
1970 |
Chemistry |
For discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates |
Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1970/press.html |
|---|
| Max Delbrück, Alfred D. Hershey & Salvador E. Luria |
1969 |
Physiology
or
Medicine |
For discoveries concerning the replication mechanism and the genetic structure of viruses |
http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1969/press.html |
|---|
| Lars Onsager |
1968 |
Chemistry |
For the discovery of the reciprocal relations bearing his name, which are fundamental for the thermodynamics of irreversible processes |
Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1968/press.html |
|---|
| Robert W. Holley & H. Gobind Khorana |
1968 |
Physiology
or
Medicine |
For interpretation of the genetic code and its function in protein synthesis |
Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1968/press.html |
|---|
| Charles B. Huggins |
1966 |
Physiology
or
Medicine |
For discoveries concerning hormonal treatment of prostatic cancer |
Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1968/press.html |
|---|
| Robert B. Woodward |
1965 |
Chemistry |
For outstanding achievements in the art of organic synthesis |
Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1965/press.html |
|---|
| Konrad Bloch |
1964 |
Physiology
or
Medicine |
For discoveries concerning the mechanism and regulation of thecholesterol and fatty acid metabolism |
Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1964/press.html |
|---|
| James D. Watson |
1962 |
Physiology
or
Medicine |
For discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material |
Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1962/press.html |
|---|