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September 30, 2016

Archived: Trending Young in New and Early Stage Investigator MIRA

Dr. Jon Lorsch
The MIRA presentation at the September 2016 Advisory Council meeting begins at 17:13.
Following up on the previous post regarding the first MIRA awards to New and Early Stage Investigators, we issued awards to a total of 94 grantees. In addition to ensuring that we are funding the highest quality science across areas associated with NIGMS’ mission, a major goal is to support a broad and diverse portfolio of research topics and investigators. One step in this effort is to make sure that existing skews in the system are not exacerbated during the MIRA selection process. To assess this, we compared the gender, race/ethnicity and age of those MIRA applicants who received an award with those of the applicants who did not receive an award, as well as with New and Early Stage Investigators who received competitive R01 awards in Fiscal Year (FY) 2015. We did not observe any significant differences in the gender or race/ethnicity distributions of the MIRA grantees as compared to the MIRA applicants who did not receive an award. Both groups were roughly 25% female and included ≤10% of underrepresented racial/ethnic groups. These proportions were also not significantly different from those of the new and early stage R01 grantees. Thus although the MIRA selection process did not yet enhance these aspects of the diversity of the awardee pool relative to the other groups of grantees, it also did not exacerbate the existing skewed distribution. We did observe significant differences among the mean ages of the MIRA grantees, MIRA applicants who did not receive an award and the R01-funded grantees. The MIRA grantees are 1.5 years younger on average than those MIRA applicants who did not receive an award (37.2 vs. 38.7 years, p<0.05), and about 2 years younger than the FY 2015 R01-funded Early Stage Investigators (37.2 vs. 39.1 years, p<0.001). The R01-funded New Investigators in FY 2015, a pool which includes a few individuals older than 60 years, average an age of 45.6 years. This selection for funding investigators earlier is a promising feature of the first round of MIRA awards to New and Early Stage Investigators. As noted at the recent meeting of our Advisory Council, where Jon presented these data, 37 years is still relatively late for investigators to be getting their first major NIH grant. We will continue to monitor this issue with the goal of further decreasing that figure.

About the Authors

Peter Preusch

Until his retirement in December 2020, Peter handled grants on the biophysics of nucleic acids and nucleoprotein complexes and on the biophysics of membranes and membrane proteins. He also managed other programs in the BBCB division and served as the point of contact for the NIGMS Collaborative Program Award for Multidisciplinary Teams (RM1) and NIGMS National and Regional Resources (R24).
Headshot of Jon Lorsch.

Jon Lorsch

As NIGMS director, Jon oversees the Institute’s research, training, and other programs. He’s committed to engaging the scientific community on a wide range of topics, including funding policies and trends, research evaluation, and workforce development.
Jake Basson

Jake Basson

Jake, who trained in biostatistics and cardiovascular genetics, is a statistical policy analyst in the NIGMS Division of Data Integration, Modeling, and Analytics. He uses a diverse suite of data science tools to study the Institute’s research portfolios, training programs, and funding policies.