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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Snowflake yeast 1

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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View Media

Podocytes from a chronically diseased kidney

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This scanning electron microscope (SEM) image shows podocytes--cells in the kidney that play a vital role in filtering waste from the bloodstream--from a patient with chronic kidney disease. Olga Troyanskaya, Princeton University and Matthias Kretzler, University of Michigan View Media

Microarray 01

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Microarrays, also called gene chips, are tools that let scientists track the activity of hundreds or thousands of genes simultaneously. Maggie Werner-Washburne, University of New Mexico, Albuquerque View Media

Zinc levels in a plant leaf

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Zinc is required for the function of more than 300 enzymes, including those that help regulate gene expression, in various organisms including humans. Suzana Car, Dartmouth College View Media

Ear hair cells derived from embryonic stem cells

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Mouse embryonic stem cells matured into this bundle of hair cells similar to the ones that transmit sound in the ear. Stefen Heller, Stanford University, via CIRM View Media

Retinal pigment epithelium derived from human ES cells

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This color-enhanced image is a scanning electron microscope image of retinal pigment epithelial (RPE) cells derived from human embryonic stem cells. David Hinton lab, University of Southern California, via CIRM View Media

Confocal microscopy image of two Drosophila ovarioles

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Ovarioles in female insects are tubes in which egg cells (called oocytes) form at one end and complete their development as they reach the other end of the tube. 2004 Olympus BioScapes Competition View Media

Fruit fly spermatids

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Developing spermatids (precursors of mature sperm cells) begin as small, round cells and mature into long-tailed, tadpole-shaped ones. Lacramioara Fabian, The Hospital for Sick Children, Toronto, Canada View Media

Brain showing hallmarks of Alzheimer's disease

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Along with blood vessels (red) and nerve cells (green), this mouse brain shows abnormal protein clumps known as plaques (blue). Alvin Gogineni, Genentech View Media

800 MHz NMR magnet

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Scientists use nuclear magnetic spectroscopy (NMR) to determine the detailed, 3D structures of molecules. Asokan Anbanandam, University of Kansas View Media

Human retinal organoid

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A replica of a human retina grown from stem cells. Kevin Eliceiri, University of Wisconsin-Madison. View Media

Honeybees marked with paint

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Researchers doing behavioral experiments with honeybees sometimes use paint or enamel to give individual bees distinguishing marks. Gene Robinson, University of Illinois at Urbana-Champaign. View Media

Chromatin in human fibroblast

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The nucleus of a human fibroblast cell with chromatin—a substance made up of DNA and proteins—shown in various colors. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media

Fungal lipase (2)

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Crystals of fungal lipase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Fruitful dyes

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These colorful, computer-generated ribbons show the backbone of a molecule that glows a fluorescent red. Roger Y. Tsien, University of California, San Diego View Media

Mouse brain 1

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A mouse brain that was genetically modified so that subpopulations of its neurons glow. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media

Zebrafish head vasculature video

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Various views of a zebrafish head with blood vessels shown in purple. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media

NMR spectrometer

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This photo shows a Varian Unity Inova 900 MHz, 21.1 T standard bore magnet Nuclear Magnetic Resonnance (NMR) spectrometer. Center for Eukaryotic Structural Genomics View Media

Automated crystal screening system

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Automated crystal screening systems such as the one shown here are becoming a common feature at synchrotron and other facilities where high-throughput crystal structure determination is being carried Southeast Collaboratory for Structural Genomics View Media

Computer sketch of bird-and-flower DNA origami

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A computer-generated sketch of a DNA origami folded into a flower-and-bird structure. See also related image 3690. Hao Yan, Arizona State University View Media

Advanced Photon Source (APS) at Argonne National Lab

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The intense X-rays produced by synchrotrons such as the Advanced Photon Source are ideally suited for protein structure determination. Southeast Collaboratory for Structural Genomics View Media

Superconducting magnet

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Superconducting magnet for NMR research, from the February 2003 profile of Dorothee Kern in Findings. Mike Lovett View Media

Computer model of cell membrane

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A computer model of the cell membrane, where the plasma membrane is red, endoplasmic reticulum is yellow, and mitochondria are blue. Bridget Wilson, University of New Mexico View Media

Fruit fly larvae brains showing tubulin

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Two fruit fly (Drosophila melanogaster) larvae brains with neurons expressing fluorescently tagged tubulin protein. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media

HeLa cells

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Multiphoton fluorescence image of cultured HeLa cells with a fluorescent protein targeted to the Golgi apparatus (orange), microtubules (green) and counterstained for DNA (cyan). National Center for Microscopy and Imaging Research (NCMIR) View Media

Human Adenovirus

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The cryo-EM structure of human adenovirus D26 (HAdV-D26) at near atomic resolution (3.7 Å), determined in collaboration with the NRAMM facility*. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media

Tracking embryonic zebrafish cells

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To better understand cell movements in developing embryos, researchers isolated cells from early zebrafish embryos and grew them as clusters. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View Media

Bacterial cells aggregated above a light-organ pore of the Hawaiian bobtail squid

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The beating of cilia on the outside of the Hawaiian bobtail squid’s light organ concentrates Vibrio fischeri cells (green) present in the seawater into aggregates near the pore-containing tis Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

DNase

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Crystals of DNase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

The nascent juvenile light organ of the Hawaiian bobtail squid

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A light organ (~0.5 mm across) of a Hawaiian bobtail squid, Euprymna scolopes, with different tissues are stained various colors. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

X-ray diffraction pattern from a crystallized cefotaxime-CCD-1 complex

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Color coding of the Drosophila brain - black background

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This image results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View Media

Fruit fly egg chamber

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A fruit fly (Drosophila melanogaster) egg chamber with microtubules shown in green and actin filaments shown in red. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media

Cryo-ET cell cross-section visualizing insulin vesicles

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On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a color-coded, 3D version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View Media

Bioluminescent imaging in adult zebrafish - lateral and overhead view

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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media

Microtubules and tau aggregates

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Microtubules (magenta) and tau protein (light blue) in a cell model of tauopathy. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media

Fluorescence in situ hybridization (FISH) in mouse ES cells shows DNA interactions

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Researchers used fluorescence in situ hybridization (FISH) to confirm the presence of long range DNA-DNA interactions in mouse embryonic stem cells. Kathrin Plath, University of California, Los Angeles View Media

Beta-galactosidase montage showing cryo-EM improvement--transparent background

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Composite image of beta-galactosidase showing how cryo-EM’s resolution has improved dramatically in recent years. Older images to the left, more recent to the right. Veronica Falconieri, Sriram Subramaniam Lab, National Cancer Institute View Media

Axolotls showing nervous system components

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Axolotls—a type of salamander—that have been genetically modified so that various parts of their nervous systems glow purple and green. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media

Mouse colon with gut bacteria

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A section of mouse colon with gut bacteria (center, in green) residing within a protective pocket. Sarkis K. Mazmanian, California Institute of Technology View Media

Bacterial cells aggregating above the light organ of the Hawaiian bobtail squid

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A light organ (~0.5 mm across) of a juvenile Hawaiian bobtail squid, Euprymna scolopes. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

HeLa cells

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Scanning electron micrograph of an apoptotic HeLa cell. Zeiss Merlin HR-SEM. National Center for Microscopy and Imaging Research View Media

TFIID complex binds DNA to start gene transcription

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Gene transcription is a process by which the genetic information encoded in DNA is transcribed into RNA. Eva Nogales, Berkeley Lab View Media

Crab larva eye

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Colorized scanning electron micrographs progressively zoom in on the eye of a crab larva. In the higher-resolution frames, bacteria are visible on the eye. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

An adult Hawaiian bobtail squid

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An adult female Hawaiian bobtail squid, Euprymna scolopes, with its mantle cavity exposed from the underside. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media

Cryo-electron tomography of a Caulobacter bacterium

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3D image of Caulobacter bacterium with various components highlighted: cell membranes (red and blue), protein shell (green), protein factories known as ribosomes (yellow), and storage granules Peter Dahlberg, Stanford University. View Media

CCP enzyme

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The enzyme CCP is found in the mitochondria of baker’s yeast. Scientists study the chemical reactions that CCP triggers, which involve a water molecule, iron, and oxygen. Protein Data Bank. View Media

Mouse retina

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What looks like the gossamer wings of a butterfly is actually the retina of a mouse, delicately snipped to lay flat and sparkling with fluorescent molecules. Tom Deerinck and Keunyoung (“Christine”) Kim, NCMIR View Media

Single-Molecule Imaging

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This is a super-resolution light microscope image taken by Hiro Hakozaki and Masa Hoshijima of NCMIR. Tom Deerinck, NCMIR View Media

Cell division and cell death

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Two cells over a 2-hour period. The one on the bottom left goes through programmed cell death, also known as apoptosis. The one on the top right goes through cell division, also called mitosis. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media