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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Color coding of the Drosophila brain - video
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This video results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View Media
Mouse Brain Cross Section
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The brain sections are treated with fluorescent antibodies specific to a particular protein and visualized using serial electron microscopy (SEM). Anton Maximov, The Scripps Research Institute, La Jolla, CA View Media
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media
An adult Hawaiian bobtail squid
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An adult female Hawaiian bobtail squid, Euprymna scolopes, with its mantle cavity exposed from the underside. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
Human skeletal muscle
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Cross section of human skeletal muscle. Image taken with a confocal fluorescent light microscope. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Network diagram of genes, cellular components and processes (labeled)
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This image shows the hierarchical ontology of genes, cellular components and processes derived from large genomic datasets. From Dutkowski et al. Janusz Dutkowski and Trey Ideker, University of California, San Diego View Media
CRISPR Illustration Frame 4
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
Dense tubular matrices in the peripheral endoplasmic reticulum (ER) 1
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Superresolution microscopy work on endoplasmic reticulum (ER) in the peripheral areas of the cell showing details of the structure and arrangement in a complex web of tubes. Jennifer Lippincott-Schwartz, Howard Hughes Medical Institute Janelia Research Campus, Virginia View Media
Mapping brain differences
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This image of the human brain uses colors and shapes to show neurological differences between two people. Arthur Toga, University of California, Los Angeles View Media
Nano-rainbow
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These vials may look like they're filled with colored water, but they really contain nanocrystals reflecting different colors under ultraviolet light. Shuming Nie, Emory University View Media
Leading cells with light
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A blue laser beam turns on a protein that helps this human cancer cell move. Responding to the stimulus, the protein, called Rac1, first creates ruffles at the edge of the cell. Yi Wu, University of North Carolina View Media
Two mouse fibroblast cells
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Two mouse fibroblasts, one of the most common types of cells in mammalian connective tissue. They play a key role in wound healing and tissue repair. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media
Ear hair cells derived from embryonic stem cells
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Mouse embryonic stem cells matured into this bundle of hair cells similar to the ones that transmit sound in the ear. Stefen Heller, Stanford University, via CIRM View Media
Fruit fly spermatids
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Developing spermatids (precursors of mature sperm cells) begin as small, round cells and mature into long-tailed, tadpole-shaped ones. Lacramioara Fabian, The Hospital for Sick Children, Toronto, Canada View Media
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 5
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media
Cryogenic storage tanks at the Coriell Institute for Medical Research
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Established in 1953, the Coriell Institute for Medical Research distributes cell lines and DNA samples to researchers around the world. Courtney Sill, Coriell Institute for Medical Research View Media
Tracking cells in a gastrulating zebrafish embryo
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During development, a zebrafish embryo is transformed from a ball of cells into a recognizable body plan by sweeping convergence and extension cell movements. This process is called gastrulation. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View Media
Staphylococcus aureus aggregating upon contact with synovial fluid
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Staphylococcus aureus bacteria (green) grouping together upon contact with synovial fluid—a viscous substance found in joints. Paul Stoodley, The Ohio State University. View Media
Microtubules in hippocampal neurons
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Microtubules (magenta) in neurons of the hippocampus, a part of the brain involved in learning and memory. Microtubules are strong, hollow fibers that provide structural support to cells. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media
Yeast cells responding to a glucose shortage
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These yeast cells were exposed to a glucose (sugar) shortage. Mike Henne, University of Texas Southwestern Medical Center. View Media
Cell-like compartments from frog eggs 5
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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media
Axolotl
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An axolotl—a type of salamander—that has been genetically modified so that its developing nervous system glows purple and its Schwann cell nuclei appear light blue. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media
Fruitful dyes
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These colorful, computer-generated ribbons show the backbone of a molecule that glows a fluorescent red. Roger Y. Tsien, University of California, San Diego View Media
Cell-like compartments emerging from scrambled frog eggs
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Cell-like compartments spontaneously emerge from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 2
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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media
NMR spectrometer
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This photo shows a Varian Unity Inova 900 MHz, 21.1 T standard bore magnet Nuclear Magnetic Resonnance (NMR) spectrometer. Center for Eukaryotic Structural Genomics View Media
EM of yeast cell division
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Cell division is an incredibly coordinated process. Matthew West and Greg Odorizzi, University of Colorado View Media
Bacterial alpha amylase
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A crystal of bacterial alpha amylase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Bioluminescent imaging in adult zebrafish - overhead view
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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media
Protein purification robot
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Irina Dementieva, a biochemist, and Youngchang Kim, a biophysicist and crystallographer, work with the first robot of its type in the U.S. to automate protein purification. Midwest Center for Structural Genomics View Media
CRISPR illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
Dynamic cryo-EM model of the human transcription preinitiation complex
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Gene transcription is a process by which information encoded in DNA is transcribed into RNA. Eva Nogales, Berkeley Lab View Media
Transmission electron microscopy showing cross-section of the node of Ranvier
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Nodes of Ranvier are short gaps in the myelin sheath surrounding myelinated nerve cells (axons). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
A molecular switch strips transcription factor from DNA
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In this video, Rice University scientists used molecular modeling with a mathematical algorithm called AWSEM (for associative memory, water-mediated, structure and energy model) and structural data to Davit Potoyan and Peter Wolynes View Media
Cryo-ET cross-section of a rat pancreas cell
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On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a 3D, color-coded version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View Media
Pig trypsin (2)
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A crystal of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Precisely Delivering Chemical Cargo to Cells
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Moving protein or other molecules to specific cells to treat or examine them has been a major biological challenge. Nature Nanotechnology View Media
Cone snail shell
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A shell from the venomous cone snail Conus omaria, which lives in the Pacific and Indian oceans and eats other snails. Kerry Matz, University of Utah View Media
Protein purification facility
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The Center for Eukaryotic Structural Genomics protein purification facility is responsible for purifying all recombinant proteins produced by the center. Center for Eukaryotic Structural Genomics View Media
A molecular interaction network in yeast 2
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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View Media
Dolly the sheep
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Scientists in Scotland were the first to clone an animal, this sheep named Dolly. She later gave birth to Bonnie, the lamb next to her. View Media
Confocal microscopy of perineuronal nets in the brain 2
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The photo shows a confocal microscopy image of perineuronal nets (PNNs), which are specialized extracellular matrix (ECM) structures in the brain. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Yeast cells with nuclear envelopes and tubulin
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Yeast cells with nuclear envelopes shown in magenta and tubulin shown in light blue. The nuclear envelope defines the borders of the nucleus, which houses DNA. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media
Tiny points of light in a quantum dot
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This fingertip-shaped group of lights is a microscopic crystal called a quantum dot. About 10,000 times thinner than a sheet of paper, the dot radiates brilliant colors under ultraviolet light. Sandra Rosenthal and James McBride, Vanderbilt University, and Stephen Pennycook, Oak Ridge National Laboratory View Media
C. elegans trapped by carnivorous fungus
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Real-time footage of Caenorhabditis elegans, a tiny roundworm, trapped by a carnivorous fungus, Arthrobotrys dactyloides. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media
Honeybees marked with paint
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Researchers doing behavioral experiments with honeybees sometimes use paint or enamel to give individual bees distinguishing marks. Gene Robinson, University of Illinois at Urbana-Champaign. View Media
Cell-like compartments emerging from scrambled frog eggs 4
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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media
Culex quinquefasciatus mosquito larva
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A mosquito larva with genes edited by CRISPR. The red-orange glow is a fluorescent protein used to track the edits. Valentino Gantz, University of California, San Diego. View Media
Mouse retina
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What looks like the gossamer wings of a butterfly is actually the retina of a mouse, delicately snipped to lay flat and sparkling with fluorescent molecules. Tom Deerinck and Keunyoung (“Christine”) Kim, NCMIR View Media
Video of Calling Cards in a mouse brain
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The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. NIH Director's Blog View Media
