Image and Video Gallery

This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Cell-like compartments emerging from scrambled frog eggs

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Cell-like compartments spontaneously emerge from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media

Yeast cells with endocytic actin patches

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Yeast cells with endocytic actin patches (green). These patches help cells take in outside material. When a cell is in interphase, patches concentrate at its ends. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media

Math from the heart

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Watch a cell ripple toward a beam of light that turns on a movement-related protein. View Media

Computer model of cell membrane

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A computer model of the cell membrane, where the plasma membrane is red, endoplasmic reticulum is yellow, and mitochondria are blue. Bridget Wilson, University of New Mexico View Media

Multivesicular bodies containing intralumenal vesicles assemble at the vacuole 1

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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View Media

Cell-like compartments from frog eggs

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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media

Zebrafish embryo showing vasculature

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A zebrafish embryo. The blue areas are cell bodies, the green lines are blood vessels, and the red glow is blood. Kevin Eliceiri, University of Wisconsin-Madison. View Media

Rabbit GPDA

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A crystal of rabbit GPDA protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Cluster analysis of mysterious protein

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Researchers use cluster analysis to study protein shape and function. Each green circle represents one potential shape of the protein mitoNEET. Patricia Jennings and Elizabeth Baxter, University of California, San Diego View Media

Video of Calling Cards in a mouse brain

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The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. NIH Director's Blog View Media

Intasome

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Salk researchers captured the structure of a protein complex called an intasome (center) that lets viruses similar to HIV establish permanent infection in their hosts. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media

Pig trypsin (2)

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A crystal of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Snowflake yeast 1

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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View Media

Neutrophil-like cells migrating in a microfluidic chip

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Neutrophil-like cells (blue) in a microfluidic chip preferentially migrating toward LTB4 over fMLP. Caroline Jones, University of Texas at Dallas. View Media

Vimentin in a quail embryo

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Confocal image showing high levels of the protein vimentin (white) at the edge zone of a quail embryo. Cell nuclei are labeled green. Andrés Garcia, Georgia Tech View Media

HeLa cells

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Multiphoton fluorescence image of cultured HeLa cells with a fluorescent protein targeted to the Golgi apparatus (orange), microtubules (green) and counterstained for DNA (cyan). National Center for Microscopy and Imaging Research (NCMIR) View Media

Automated Worm Sorter - 4

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Georgia Tech associate professor Hang Lu holds a microfluidic chip that is part of a system that uses artificial intelligence and cutting-edge image processing to automatically examine large number of Georgia Tech/Gary Meek View Media

Thermotoga maritima and its metabolic network

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A combination of protein structures determined experimentally and computationally shows us the complete metabolic network of a heat-loving bacterium. View Media

Mouse retina

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What looks like the gossamer wings of a butterfly is actually the retina of a mouse, delicately snipped to lay flat and sparkling with fluorescent molecules. Tom Deerinck and Keunyoung (“Christine”) Kim, NCMIR View Media

3D reconstruction of the Golgi apparatus in a pancreas cell

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Researchers used cryo-electron tomography (cryo-ET) to capture images of a rat pancreas cell that were then compiled and color-coded to produce a 3D reconstruction. Xianjun Zhang, University of Southern California. View Media

Protein purification robot

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Irina Dementieva, a biochemist, and Youngchang Kim, a biophysicist and crystallographer, work with the first robot of its type in the U.S. to automate protein purification. Midwest Center for Structural Genomics View Media

Electrode probe on mouse Huntington's muscle cell

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Using an electrode, researchers apply an electrical pulse onto a piece of muscle tissue affected by Huntington's disease. Grigor Varuzhanyan and Andrew A. Voss, California State Polytechnic University View Media

TEM cross-section of C. elegans (roundworm)

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The worm Caenorhabditis elegans is a popular laboratory animal because its small size and fairly simple body make it easy to study. Piali Sengupta, Brandeis University View Media

Cytonemes in developing fruit fly cells

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Scientists have long known that multicellular organisms use biological molecules produced by one cell and sensed by another to transmit messages that, for instance, guide proper development of organs Sougata Roy, University of California, San Francisco View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Bacteriophage P22 capsid

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Cryo-electron microscopy (cryo-EM) has the power to capture details of proteins and other small biological structures at the molecular level. This image shows proteins in the capsid, or outer co Dr. Wah Chiu, Baylor College of Medicine View Media

Mapping brain differences

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This image of the human brain uses colors and shapes to show neurological differences between two people. Arthur Toga, University of California, Los Angeles View Media

800 MHz NMR magnet

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Scientists use nuclear magnetic spectroscopy (NMR) to determine the detailed, 3D structures of molecules. Asokan Anbanandam, University of Kansas View Media

Electrostatic map of the adeno-associated virus

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The new highly efficient parallelized DelPhi software was used to calculate the potential map distribution of an entire virus, the adeno-associated virus, which is made up of more than 484,000 atoms. Emil Alexov, Clemson University View Media

Chromium X-ray source

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In the determination of protein structures by X-ray crystallography, this unique soft (l = 2.29Å) X-ray source is used to collect anomalous scattering data from protein crystals containing light atoms The Southeast Collaboratory for Structural Genomics View Media

Human endoplasmic reticulum membrane protein complex

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A 3D model of the human endoplasmic reticulum membrane protein complex (EMC) that identifies its nine essential subunits. Rebecca Voorhees, California Institute of Technology. View Media

Natural nanomachine in action

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Using a supercomputer to simulate the movement of atoms in a ribosome, researchers looked into the core of this protein-making nanomachine and took snapshots. Kevin Sanbonmatsu, Los Alamos National Laboratory View Media

Arachnoidiscus diatom

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An Arachnoidiscus diatom with a diameter of 190µm. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Cell-free protein synthesizers

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Both instruments shown were developed by CellFree Sciences of Yokohama, Japan. Center for Eukaryotic Structural Genomics View Media

Protein purification robot in action 01

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A robot is transferring 96 purification columns to a vacuum manifold for subsequent purification procedures. The Northeast Collaboratory for Structural Genomics View Media

Capillary protein crystallization robot

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This ACAPELLA robot for capillary protein crystallization grows protein crystals, freezes them, and centers them without manual intervention. Structural Genomics of Pathogenic Protozoa Consortium View Media

A molecular interaction network in yeast 3

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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View Media

Honeybees marked with paint

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Researchers doing behavioral experiments with honeybees sometimes use paint or enamel to give individual bees distinguishing marks. Gene Robinson, University of Illinois at Urbana-Champaign. View Media

Cas9 protein involved in the CRISPR gene-editing technology

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In the gene-editing tool CRISPR, a small strand of RNA identifies a specific chunk of DNA. Janet Iwasa View Media

Beta-galactosidase montage showing cryo-EM improvement--gradient background

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Composite image of beta-galactosidase showing how cryo-EM’s resolution has improved dramatically in recent years. Older images to the left, more recent to the right. Veronica Falconieri, Sriram Subramaniam Lab, National Cancer Institute View Media

Zebrafish head vasculature

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A zebrafish head with blood vessels shown in purple. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media

Pig alpha amylase

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Crystals of porcine alpha amylase protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media

Tracking embryonic zebrafish cells

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To better understand cell movements in developing embryos, researchers isolated cells from early zebrafish embryos and grew them as clusters. Liliana Solnica-Krezel, Washington University School of Medicine in St. Louis. View Media

Multivesicular bodies containing intralumenal vesicles assemble at the vacuole 2

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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View Media

NMR spectrometer

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This photo shows a Varian Unity Inova 900 MHz, 21.1 T standard bore magnet Nuclear Magnetic Resonnance (NMR) spectrometer. Center for Eukaryotic Structural Genomics View Media

Color coding of the Drosophila brain - black background

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This image results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View Media

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