National Institute of
Switch to Gallery View
Image and Video Gallery
This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
High-throughput protein structure determination pipeline
2364
This slide shows the technologies that the Joint Center for Structural Genomics developed for going from gene to structure and how the technologies have been integrated into a high-throughput pipeline Joint Center for Structural Genomics View Media
Wild-type and mutant fruit fly ovaries
6806
The two large, central, round shapes are ovaries from a typical fruit fly (Drosophila melanogaster). Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View Media
Culex quinquefasciatus mosquito larva
6769
A mosquito larva with genes edited by CRISPR. The red-orange glow is a fluorescent protein used to track the edits. Valentino Gantz, University of California, San Diego. View Media
Cell-like compartments emerging from scrambled frog eggs 4
6590
Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media
HIV-1 virus in the colon
3571
A tomographic reconstruction of the colon shows the location of large pools of HIV-1 virus particles (in blue) located in the spaces between adjacent cells. Mark Ladinsky, California Institute of Technology View Media
Protein purification robot in action 01
2369
A robot is transferring 96 purification columns to a vacuum manifold for subsequent purification procedures. The Northeast Collaboratory for Structural Genomics View Media
CRISPR illustration
3719
This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
Petri dish containing C. elegans
6751
This Petri dish contains microscopic roundworms called Caenorhabditis elegans. Researchers used these particular worms to study how C. H. Robert Horvitz and Dipon Ghosh, Massachusetts Institute of Technology. View Media
Cell division and cell death
6790
Two cells over a 2-hour period. The one on the bottom left goes through programmed cell death, also known as apoptosis. The one on the top right goes through cell division, also called mitosis. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media
Crab larva eye
1251
Colorized scanning electron micrographs progressively zoom in on the eye of a crab larva. In the higher-resolution frames, bacteria are visible on the eye. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media
Mouse brain 3
6931
Various views of a mouse brain that was genetically modified so that subpopulations of its neurons glow. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View Media
Precisely Delivering Chemical Cargo to Cells
3779
Moving protein or other molecules to specific cells to treat or examine them has been a major biological challenge. Nature Nanotechnology View Media
A molecular interaction network in yeast 2
3732
The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View Media
Regenerating lizard tail
6968
The interior of a regenerating lizard tail 14 days after the original tail was amputated. Thomas Lozito, University of Southern California. View Media
3D image of actin in a cell
3749
Actin is an essential protein in a cell's skeleton (cytoskeleton). It forms a dense network of thin filaments in the cell. Xiaowei Zhuang, Howard Hughes Medical Institute, Harvard University View Media
Transmission electron microscopy of myelinated axons with ECM between the axons
3736
The extracellular matrix (ECM) is most prevalent in connective tissues but also is present between the stems (axons) of nerve cells, as shown here. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Multivesicular bodies containing intralumenal vesicles assemble at the vacuole 1
5769
Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View Media
X-ray crystallography
2511
X-ray crystallography allows researchers to see structures too small to be seen by even the most powerful microscopes. Crabtree + Company View Media
Fruit fly nurse cells transporting their contents during egg development
6754
In many animals, the egg cell develops alongside sister cells. Adam C. Martin, Massachusetts Institute of Technology. View Media
Fly cells
3594
If a picture is worth a thousand words, what's a movie worth? Denise Montell, Johns Hopkins University School of Medicine View Media
Protein crystals
1060
Structural biologists create crystals of proteins, shown here, as a first step in a process called X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Plasma-Derived Membrane Vesicles
5887
This fiery image doesn’t come from inside a bubbling volcano. Instead, it shows animal cells caught in the act of making bubbles, or blebbing. Jeanne Stachowiak, University of Texas at Austin View Media
Bovine milk alpha-lactalbumin (1)
2397
A crystal of bovine milk alpha-lactalbumin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
Multivesicular bodies containing intralumenal vesicles assemble at the vacuole 2
5768
Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View Media
CRISPR Illustration Frame 1
6465
This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. This is the first frame in a series of four. National Institute of General Medical Sciences. View Media
CRISPR Illustration Frame 3
6487
This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View Media
Bioluminescent imaging in adult zebrafish - lateral and overhead view
3556
Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media
Chromatin in human tenocyte
6893
The nucleus of a degenerating human tendon cell, also known as a tenocyte. It has been color-coded based on the density of chromatin—a substance made up of DNA and proteins. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View Media
Video of Calling Cards in a mouse brain
6781
The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. NIH Director's Blog View Media
Natural nanomachine in action
2336
Using a supercomputer to simulate the movement of atoms in a ribosome, researchers looked into the core of this protein-making nanomachine and took snapshots. Kevin Sanbonmatsu, Los Alamos National Laboratory View Media
Hen egg lysozyme (1)
2396
Crystals of hen egg lysozyme protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View Media
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1
3413
X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media
Nano-rainbow
2326
These vials may look like they're filled with colored water, but they really contain nanocrystals reflecting different colors under ultraviolet light. Shuming Nie, Emory University View Media
Flagellated bacterial cells
7014
Vibrio fischeri (2 mm in length) is the exclusive symbiotic partner of the Hawaiian bobtail squid, Euprymna scolopes. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
Dying melanoma cells
6966
Melanoma (skin cancer) cells undergoing programmed cell death, also called apoptosis. This process was triggered by raising the pH of the medium that the cells were growing in. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media
Honeybees marked with paint
6756
Researchers doing behavioral experiments with honeybees sometimes use paint or enamel to give individual bees distinguishing marks. Gene Robinson, University of Illinois at Urbana-Champaign. View Media
Calling Cards in a mouse brain
6780
The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. Allen Yen, Lab of Joseph Dougherty, Washington University School of Medicine in St. Louis. View Media
Cell-like compartments emerging from scrambled frog eggs
6587
Cell-like compartments spontaneously emerge from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media
Cryo-ET cross-section of a rat pancreas cell
6608
On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a 3D, color-coded version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View Media
Introduction to Genome Editing Using CRISPR/Cas9
5815
Genome editing using CRISPR/Cas9 is a rapidly expanding field of scientific research with emerging applications in disease treatment, medical therapeutics and bioenergy, just to name a few. Janet Iwasa View Media
Yeast cells with nuclei and contractile rings
6792
Yeast cells with nuclei shown in green and contractile rings shown in magenta. Nuclei store DNA, and contractile rings help cells divide. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media
Bacterial cells migrating through the tissues of the squid light organ
7015
Vibrio fischeri cells (~ 2 mm), labeled with green fluorescent protein (GFP), passing through a very narrow bottleneck in the tissues (red) of the Hawaiian bobtail squid, Euprymna scolope Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
Dolly the sheep
2690
Scientists in Scotland were the first to clone an animal, this sheep named Dolly. She later gave birth to Bonnie, the lamb next to her. View Media
Cryo-ET cell cross-section visualizing insulin vesicles
6607
On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a color-coded, 3D version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View Media
Computer algorithm
3458
This computer algorithm plots all feasible small carbon-based molecules as though they were cities on a map and identifies huge, unexplored spaces that may help fuel research into new drug therapies. Aaron Virshup, Julia Contreras-Garcia, Peter Wipf, Weitao Yang and David Beratan, University of Pittsburgh Center for Chemical Methodologies and Library Development View Media
Capillary protein crystallization robot
2357
This ACAPELLA robot for capillary protein crystallization grows protein crystals, freezes them, and centers them without manual intervention. Structural Genomics of Pathogenic Protozoa Consortium View Media
Adult and juvenile Hawaiian bobtail squids
7010
An adult Hawaiian bobtail squid, Euprymna scolopes, (~4 cm) surrounded by newly hatched juveniles (~2 mm) in a bowl of seawater.Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View Media
Heart rates time series image
3596
These time series show the heart rates of four different individuals. Madalena Costa and Ary Goldberger, Beth Israel Deaconess Medical Center View Media
Confocal microscopy of perineuronal nets in the brain 1
3741
The photo shows a confocal microscopy image of perineuronal nets (PNNs), which are specialized extracellular matrix (ECM) structures in the brain. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Superconducting magnet
1120
Superconducting magnet for NMR research, from the February 2003 profile of Dorothee Kern in Findings. Mike Lovett View Media
