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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Protein folding video
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Proteins are long chains of amino acids. Each protein has a unique amino acid sequence. It is still a mystery how a protein folds into the proper shape based on its sequence. Theoretical and Computational Biophysics Group View MediaCryo-electron tomography of a Caulobacter bacterium
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3D image of Caulobacter bacterium with various components highlighted: cell membranes (red and blue), protein shell (green), protein factories known as ribosomes (yellow), and storage granules Peter Dahlberg, Stanford University. View MediaNuclear Lamina
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The 3D single-molecule super-resolution reconstruction of the entire nuclear lamina in a HeLa cell was acquired using the TILT3D platform. Anna-Karin Gustavsson, Ph.D. View MediaX-ray diffraction pattern from a crystallized cefotaxime-CCD-1 complex
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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View MediaBrain showing hallmarks of Alzheimer's disease
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Along with blood vessels (red) and nerve cells (green), this mouse brain shows abnormal protein clumps known as plaques (blue). Alvin Gogineni, Genentech View MediaSoft X-ray tomography of a pancreatic beta cell
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A color-coded, 3D model of a rat pancreatic β cell. This type of cell produces insulin, a hormone that helps regulate blood sugar. Carolyn Larabell, University of California, San Francisco. View MediaCell-free protein synthesizers
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Both instruments shown were developed by CellFree Sciences of Yokohama, Japan. Center for Eukaryotic Structural Genomics View MediaCell-like compartments from frog eggs 3
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Cell-like compartments that spontaneously emerged from scrambled frog eggs. Endoplasmic reticulum (red) and microtubules (green) are visible. Image created using epifluorescence microscopy. Xianrui Cheng, Stanford University School of Medicine. View MediaYeast cells entering mitosis
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Yeast cells entering mitosis, also known as cell division. The green and magenta dots are two proteins that play important roles in mitosis. They show where the cells will split. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View MediaElectrostatic map of human spermine synthase
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From PDB entry 3c6k, Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine. Emil Alexov, Clemson University View MediaDividing yeast cells with spindle pole bodies and contractile rings
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During cell division, spindle pole bodies (glowing dots) move toward the ends of yeast cells to separate copied genetic information. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View MediaCell-like compartments from frog eggs
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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View MediaMultivesicular bodies containing intralumenal vesicles assemble at the vacuole 1
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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View MediaZebrafish head vasculature video
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Various views of a zebrafish head with blood vessels shown in purple. Prayag Murawala, MDI Biological Laboratory and Hannover Medical School. View MediaA molecular interaction network in yeast 1
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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View MediaCRISPR Illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaCytonemes in developing fruit fly cells
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Scientists have long known that multicellular organisms use biological molecules produced by one cell and sensed by another to transmit messages that, for instance, guide proper development of organs Sougata Roy, University of California, San Francisco View MediaPhagosome in macrophage cell
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A sensor particle being engulfed by a macrophage—an immune cell—and encapsuled in a compartment called a phagosome. The phagosome then fuses with lysosomes—another type of compartment. Yan Yu, Indiana University, Bloomington. View MediaFruit fly egg chamber
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A fruit fly (Drosophila melanogaster) egg chamber with microtubules shown in green and actin filaments shown in red. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View MediaColor coding of the Drosophila brain - image
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This image results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View MediaStaphylococcus aureus in the porous coating of a femoral hip stem
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Staphylococcus aureus bacteria (blue) on the porous coating of a femoral hip stem used in hip replacement surgery. Paul Stoodley, The Ohio State University. View MediaPig trypsin (1)
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A crystal of porcine trypsin protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaInsulin production and fat sensing in fruit flies
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Fourteen neurons (magenta) in the adult Drosophila brain produce insulin, and fat tissue sends packets of lipids to the brain via the lipoprotein carriers (green). Akhila Rajan, Fred Hutchinson Cancer Center View MediaGolden gene chips
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A team of chemists and physicists used nanotechnology and DNA's ability to self-assemble with matching RNA to create a new kind of chip for measuring gene activity. Hao Yan and Yonggang Ke, Arizona State University View MediaHuman blood cells with Borrelia hermsii, a bacterium that causes relapsing fever
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Relapsing fever is caused by a bacterium and transmitted by certain soft-bodied ticks or body lice. The disease is seldom fatal in humans, but it can be very serious and prolonged. NIAID View MediaAutomated crystal screening system
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Automated crystal screening systems such as the one shown here are becoming a common feature at synchrotron and other facilities where high-throughput crystal structure determination is being carried Southeast Collaboratory for Structural Genomics View MediaVimentin in a quail embryo
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Video of high-resolution confocal images depicting vimentin immunofluorescence (green) and nuclei (blue) at the edge of a quail embryo yolk. Andrés Garcia, Georgia Tech View MediaProtein crystals
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Structural biologists create crystals of proteins, shown here, as a first step in a process called X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaDinosaur evolutionary tree
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Analysis of 68 million-year-old collagen molecule fragments preserved in a T. Chris Organ, Harvard University View MediaComputer model of cell membrane
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A computer model of the cell membrane, where the plasma membrane is red, endoplasmic reticulum is yellow, and mitochondria are blue. Bridget Wilson, University of New Mexico View MediaMouse retina
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What looks like the gossamer wings of a butterfly is actually the retina of a mouse, delicately snipped to lay flat and sparkling with fluorescent molecules. Tom Deerinck and Keunyoung (“Christine”) Kim, NCMIR View MediaHeart rates time series image
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These time series show the heart rates of four different individuals. Madalena Costa and Ary Goldberger, Beth Israel Deaconess Medical Center View MediaScientists display X-ray diffraction pattern obtained with split X-ray beamline
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Scientists from Argonne National Laboratory's Advanced Photon Source (APS) display the first X-ray diffraction pattern obtained from a protein crystal using a split X-ray beam, the first of its kind a GM/CA Collaborative Access Team View MediaTransmission electron microscopy showing cross-section of the node of Ranvier
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Nodes of Ranvier are short gaps in the myelin sheath surrounding myelinated nerve cells (axons). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaFat cells (red) and blood vessels (green)
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A mouse's fat cells (red) are shown surrounded by a network of blood vessels (green). Daniela Malide, National Heart, Lung, and Blood Institute, National Institutes of Health View MediaPrecisely Delivering Chemical Cargo to Cells
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Moving protein or other molecules to specific cells to treat or examine them has been a major biological challenge. Nature Nanotechnology View MediaYeast cells with nuclei and contractile rings
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Yeast cells with nuclei shown in green and contractile rings shown in magenta. Nuclei store DNA, and contractile rings help cells divide. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View MediaIntasome
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Salk researchers captured the structure of a protein complex called an intasome (center) that lets viruses similar to HIV establish permanent infection in their hosts. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View MediaSpace-filling model of a cefotaxime-CCD-1 complex
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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View MediaSnowflake yeast 1
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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View MediaBacterial cells aggregated above a light-organ pore of the Hawaiian bobtail squid
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The beating of cilia on the outside of the Hawaiian bobtail squid’s light organ concentrates Vibrio fischeri cells (green) present in the seawater into aggregates near the pore-containing tis Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaElectrostatic map of the adeno-associated virus
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The new highly efficient parallelized DelPhi software was used to calculate the potential map distribution of an entire virus, the adeno-associated virus, which is made up of more than 484,000 atoms. Emil Alexov, Clemson University View MediaMyosin V binding to actin
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This simulation of myosin V binding to actin was created using the software tool Protein Mechanica. Simbios, NIH Center for Biomedical Computation at Stanford View Media3D image of actin in a cell
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Actin is an essential protein in a cell's skeleton (cytoskeleton). It forms a dense network of thin filaments in the cell. Xiaowei Zhuang, Howard Hughes Medical Institute, Harvard University View MediaTEM cross-section of C. elegans (roundworm)
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The worm Caenorhabditis elegans is a popular laboratory animal because its small size and fairly simple body make it easy to study. Piali Sengupta, Brandeis University View MediaYeast cells with Fimbrin Fim1
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Yeast cells with the protein Fimbrin Fim1 shown in magenta. This protein plays a role in cell division. This image was captured using wide-field microscopy with deconvolution.Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media
Leading cells with light
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A blue laser beam turns on a protein that helps this human cancer cell move. Responding to the stimulus, the protein, called Rac1, first creates ruffles at the edge of the cell. Yi Wu, University of North Carolina View MediaNano-rainbow
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These vials may look like they're filled with colored water, but they really contain nanocrystals reflecting different colors under ultraviolet light. Shuming Nie, Emory University View MediaHuman retinal organoid
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A replica of a human retina grown from stem cells. Kevin Eliceiri, University of Wisconsin-Madison. View MediaMouse brain slice showing nerve cells
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A 20-µm thick section of mouse midbrain. The nerve cells are transparent and weren’t stained. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media