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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
Yeast cells responding to a glucose shortage
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These yeast cells were exposed to a glucose (sugar) shortage. Mike Henne, University of Texas Southwestern Medical Center. View MediaMapping disease spread
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How far and fast an infectious disease spreads across a community depends on many factors, including transportation. These U.S. David Chrest, RTI International View MediaX-ray diffraction pattern from a crystallized cefotaxime-CCD-1 complex
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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View MediaElectrode probe on mouse Huntington's muscle cell
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Using an electrode, researchers apply an electrical pulse onto a piece of muscle tissue affected by Huntington's disease. Grigor Varuzhanyan and Andrew A. Voss, California State Polytechnic University View MediaMultivesicular bodies containing intralumenal vesicles assemble at the vacuole 2
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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View MediaGlow-in-the-dark salamanders
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These six-month-old axolotls, a kind of salamander, glow green and blue under ultraviolet light. That's because they were genetically modified to make harmless green fluorescent protein, or GFP. View MediaCrane fly spermatocyte undergoing meiosis
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A crane fly spermatocyte during metaphase of meiosis-I, a step in the production of sperm. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaCRISPR
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RNA incorporated into the CRISPR surveillance complex is positioned to scan across foreign DNA. Cryo-EM density from a 3Å reconstruction is shown as a yellow mesh. NRAMM National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View MediaCrab larva eye
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Colorized scanning electron micrographs progressively zoom in on the eye of a crab larva. In the higher-resolution frames, bacteria are visible on the eye. Tina Weatherby Carvalho, University of Hawaii at Manoa View MediaCRISPR Illustration
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaHIV-1 virus in the colon
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A tomographic reconstruction of the colon shows the location of large pools of HIV-1 virus particles (in blue) located in the spaces between adjacent cells. Mark Ladinsky, California Institute of Technology View MediaCluster analysis of mysterious protein
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Researchers use cluster analysis to study protein shape and function. Each green circle represents one potential shape of the protein mitoNEET. Patricia Jennings and Elizabeth Baxter, University of California, San Diego View MediaMapping brain differences
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This image of the human brain uses colors and shapes to show neurological differences between two people. Arthur Toga, University of California, Los Angeles View MediaRNase A (2)
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A crystal of RNase A protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaSnowflake yeast 2
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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View MediaYeast cells with accumulated cell wall material
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Yeast cells that abnormally accumulate cell wall material (blue) at their ends and, when preparing to divide, in their middles. This image was captured using wide-field microscopy with deconvolution. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View MediaCryo-ET cross-section of a rat pancreas cell
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On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a 3D, color-coded version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View MediaAnnotated TEM cross-section of C. elegans (roundworm)
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The worm Caenorhabditis elegans is a popular laboratory animal because its small size and fairly simple body make it easy to study. Piali Sengupta, Brandeis University View MediaEar hair cells derived from embryonic stem cells
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Mouse embryonic stem cells matured into this bundle of hair cells similar to the ones that transmit sound in the ear. Stefen Heller, Stanford University, via CIRM View MediaHeLa cells
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Multiphoton fluorescence image of HeLa cells with cytoskeletal microtubules (magenta) and DNA (cyan). Nikon RTS2000MP custom laser scanning microscope. National Center for Microscopy and Imaging Research (NCMIR) View MediaHen egg lysozyme (2)
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A crystal of hen egg lysozyme protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaCell-like compartments from frog eggs 2
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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View MediaA molecular interaction network in yeast 2
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The image visualizes a part of the yeast molecular interaction network. Keiichiro Ono, UCSD View MediaSingle-cell “radios” video
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Individual cells are color-coded based on their identity and signaling activity using a protein circuit technology developed by the Coyle Lab. Scott Coyle, University of Wisconsin-Madison. View MediaBacteriophage P22 capsid
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Cryo-electron microscopy (cryo-EM) has the power to capture details of proteins and other small biological structures at the molecular level. This image shows proteins in the capsid, or outer co Dr. Wah Chiu, Baylor College of Medicine View MediaHeLa cells
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Scanning electron micrograph of an apoptotic HeLa cell. Zeiss Merlin HR-SEM. National Center for Microscopy and Imaging Research View MediaProtein purification facility
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The Center for Eukaryotic Structural Genomics protein purification facility is responsible for purifying all recombinant proteins produced by the center. Center for Eukaryotic Structural Genomics View MediaRabbit GPDA
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A crystal of rabbit GPDA protein created for X-ray crystallography, which can reveal detailed, three-dimensional protein structures. Alex McPherson, University of California, Irvine View MediaC. elegans with blue and yellow lights in the background
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These microscopic roundworms, called Caenorhabditis elegans, lack eyes and the opsin proteins used by visual systems to detect colors. H. Robert Horvitz and Dipon Ghosh, Massachusetts Institute of Technology. View MediaMouse liver labeled with fluorescent probe
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A mouse liver glows after being tagged with specially designed infrared-fluorescent protein (IFP). Xiaokun Shu, University of California, San Diego View MediaLeading cells with light
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A blue laser beam turns on a protein that helps this human cancer cell move. Responding to the stimulus, the protein, called Rac1, first creates ruffles at the edge of the cell. Yi Wu, University of North Carolina View MediaTEM cross-section of C. elegans (roundworm)
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The worm Caenorhabditis elegans is a popular laboratory animal because its small size and fairly simple body make it easy to study. Piali Sengupta, Brandeis University View MediaMouse colon with gut bacteria
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A section of mouse colon with gut bacteria (center, in green) residing within a protective pocket. Sarkis K. Mazmanian, California Institute of Technology View MediaPetri dish containing C. elegans
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This Petri dish contains microscopic roundworms called Caenorhabditis elegans. Researchers used these particular worms to study how C. H. Robert Horvitz and Dipon Ghosh, Massachusetts Institute of Technology. View MediaColor coding of the Drosophila brain - black background
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This image results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View MediaSelf-organizing proteins
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Under the microscope, an E. coli cell lights up like a fireball. Each bright dot marks a surface protein that tells the bacteria to move toward or away from nearby food and toxins. View MediaBacterial symbionts colonizing the crypts of a juvenile Hawaiian bobtail squid light organ
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A light organ (~0.5 mm across) of a Hawaiian bobtail squid, Euprymna scolopes, stained blue. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaCRISPR Illustration Frame 2
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This illustration shows, in simplified terms, how the CRISPR-Cas9 system can be used as a gene-editing tool. National Institute of General Medical Sciences. View MediaFruitful dyes
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These colorful, computer-generated ribbons show the backbone of a molecule that glows a fluorescent red. Roger Y. Tsien, University of California, San Diego View MediaFlagellated bacterial cells
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Vibrio fischeri (2 mm in length) is the exclusive symbiotic partner of the Hawaiian bobtail squid, Euprymna scolopes. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaHawaiian bobtail squid
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An adult Hawaiian bobtail squid, Euprymna scolopes, swimming next to a submerged hand. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaMicrofluidic chip
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Microfluidic chips have many uses in biology labs. Jeff Hasty Lab, UC San Diego View MediaHuman embryonic stem cells on feeder cells
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This fluorescent microscope image shows human embryonic stem cells whose nuclei are stained green. Blue staining shows the surrounding supportive feeder cells. Michael Longaker lab, Stanford University School of Medicine, via CIRM View MediaAdult Hawaiian bobtail squid burying in the sand
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Each morning, the nocturnal Hawaiian bobtail squid, Euprymna scolopes, hides from predators by digging into the sand. At dusk, it leaves the sand again to hunt. Margaret J. McFall-Ngai, Carnegie Institution for Science/California Institute of Technology, and Edward G. Ruby, California Institute of Technology. View MediaBioluminescent imaging in adult zebrafish - lateral and overhead view
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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View MediaProtein purification robot in action 01
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A robot is transferring 96 purification columns to a vacuum manifold for subsequent purification procedures. The Northeast Collaboratory for Structural Genomics View MediaThermotoga maritima and its metabolic network
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A combination of protein structures determined experimentally and computationally shows us the complete metabolic network of a heat-loving bacterium. View MediaModeling disease spread
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What looks like a Native American dream catcher is really a network of social interactions within a community. Stephen Eubank, University of Virginia Biocomplexity Institute (formerly Virginia Bioinformatics Institute) View MediaFruit fly nurse cells during egg development
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In many animals, the egg cell develops alongside sister cells. Adam C. Martin, Massachusetts Institute of Technology. View MediaStudent overseeing protein cloning robot
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Student Christina Hueneke of the Midwest Center for Structural Genomics is overseeing a protein cloning robot. Midwest Center for Structural Genomics View Media