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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Plasma membrane (with labels)

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The plasma membrane is a cell's protective barrier. See image 2523 for an unlabeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Shiga toxin being sorted inside a cell

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Shiga toxin (green) is sorted from the endosome into membrane tubules (red), which then pinch off and move to the Golgi apparatus. Somshuvra Mukhopadhyay, The University of Texas at Austin, and Adam D. Linstedt, Carnegie Mellon University View Media

Active Site of E. coli response regulator PhoB

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Active site of E. coli response regulator PhoB. Ann Stock, Rutgers University View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 1

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Space-filling model of a cefotaxime-CCD-1 complex

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CCD-1 is an enzyme produced by the bacterium Clostridioides difficile that helps it resist antibiotics. Keith Hodgson, Stanford University. View Media

Bioluminescent imaging in adult zebrafish - overhead view

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Luciferase-based imaging enables visualization and quantification of internal organs and transplanted cells in live adult zebrafish. Kenneth Poss, Duke University View Media

Dynein moving along microtubules

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Dynein (green) is a motor protein that “walks” along microtubules (red, part of the cytoskeleton) and carries its cargo along with it. This video was captured through fluorescence microscopy. Morgan DeSantis, University of Michigan. View Media

Kinases (with labels)

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Kinases are enzymes that add phosphate groups (red-yellow structures) to proteins (green), assigning the proteins a code. Crabtree + Company View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 2

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Nucleolus subcompartments spontaneously self-assemble 2

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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media

Activation energy

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To become products, reactants must overcome an energy hill. See image 2526 for a labeled version of this illustration. Featured in The Chemistry of Health. Crabtree + Company View Media

Himastatin

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A model of the molecule himastatin, which was first isolated from the bacterium Streptomyces himastatinicus. Himastatin shows antibiotic activity. Mohammad Movassaghi, Massachusetts Institute of Technology. View Media

Computer algorithm

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This computer algorithm plots all feasible small carbon-based molecules as though they were cities on a map and identifies huge, unexplored spaces that may help fuel research into new drug therapies. Aaron Virshup, Julia Contreras-Garcia, Peter Wipf, Weitao Yang and David Beratan, University of Pittsburgh Center for Chemical Methodologies and Library Development View Media

HIV Capsid

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This image is a computer-generated model of the approximately 4.2 million atoms of the HIV capsid, the shell that contains the virus' genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View Media

Carbon building blocks (with examples)

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The arrangement of identical molecular components can make a dramatic difference. For example, carbon atoms can be arranged into dull graphite (left) or sparkly diamonds (right). Crabtree + Company View Media

White Poppy

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A white poppy. View cropped image of a poppy here 3423. Judy Coyle, Donald Danforth Plant Science Center View Media

White Poppy (cropped)

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A cropped image of a white poppy. View poppy uncropped here 3424. Judy Coyle, Donald Danforth Plant Science Center View Media

Nucleolus subcompartments spontaneously self-assemble 1

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The nucleolus is a small but very important protein complex located in the cell's nucleus. Nilesh Vaidya, Princeton University View Media

Cryo-electron microscopy revealing the "wasabi receptor"

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The TRPA1 protein is responsible for the burn you feel when you taste a bite of sushi topped with wasabi. Jean-Paul Armache, UCSF View Media

See how immune cell acid destroys bacterial proteins

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This animation shows the effect of exposure to hypochlorous acid, which is found in certain types of immune cells, on bacterial proteins. American Chemistry Council View Media

In vitro assembly of a cell-signaling pathway

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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View Media

Enzyme reaction

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Enzymes speed up chemical reactions by reducing the amount of energy needed for the reactions. NIGMS View Media

Red Poppy

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A red poppy. Judy Coyle, Donald Danforth Plant Science Center View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 3

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 6

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Circadian rhythms and the SCN

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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. NIGMS View Media

Antibiotic-surviving bacteria

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Colonies of bacteria growing despite high concentrations of antibiotics. These colonies are visible both by eye, as seen on the left, and by bioluminescence imaging, as seen on the right. Paul Stoodley, The Ohio State University. View Media

Cancer Cells Glowing from Luciferin

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The activator cancer cell culture, right, contains a chemical that causes the cells to emit light when in the presence of immune cells. Mark Sellmyer, Stanford University School of Medicine View Media

A Bacillus subtilis biofilm grown in a Petri dish

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Bacterial biofilms are tightly knit communities of bacterial cells growing on, for example, solid surfaces, such as in water pipes or on teeth. Gürol Süel, UCSD View Media

Ciclo circadiano de un adolescente típico

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Los ritmos circadianos son cambios físicos, mentales y conductuales que siguen un ciclo de 24 horas. NIGMS View Media

Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 04

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor 7

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X-ray co-crystal structure of Src kinase bound to a DNA-templated macrocycle inhibitor. Markus A. Seeliger, Stony Brook University Medical School and David R. Liu, Harvard University View Media

Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 01

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Kinases

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Kinases are enzymes that add phosphate groups (red-yellow structures) to proteins (green), assigning the proteins a code. Crabtree + Company View Media

Kinesin moves cellular cargo

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A protein called kinesin (blue) is in charge of moving cargo around inside cells and helping them divide. Charles Sindelar, Yale University View Media

ATP synthase

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The world's smallest motor, ATP synthase, generates energy for the cell. See image 2518 for a labeled version of this illustration. Crabtree + Company View Media

Dose response curves

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Dose-response curves determine how much of a drug (X-axis) causes a particular effect, or a side effect, in the body (Y-axis). Featured in Medicines By Design. Crabtree + Company View Media

Enzyme transition states

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The molecule on the left is an electrostatic potential map of the van der Waals surface of the transition state for human purine nucleoside phosphorylase. Vern Schramm, Albert Einstein College of Medicine of Yeshiva University View Media

Anti-tumor drug ecteinascidin 743 (ET-743), structure without hydrogens 03

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Fruit fly brain responds to adipokines

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Drosophila adult brain showing that an adipokine (fat hormone) generates a response from neurons (aqua) and regulates insulin-producing neurons (red).
Akhila Rajan, Fred Hutchinson Cancer Center View Media

Precisely Delivering Chemical Cargo to Cells

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Moving protein or other molecules to specific cells to treat or examine them has been a major biological challenge. Nature Nanotechnology View Media

Average teen circadian cycle

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Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. Typical circadian rhythms lead to high energy during the middle of the day (10 a.m. NIGMS View Media

O2 reacting with a flavin-dependent enzyme

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Department of Biological Chemistry, University of Michigan View Media

Brain waves of a patient anesthetized with propofol

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A representation of a patient’s brain waves after receiving the anesthetic propofol. Emery N. Brown, M.D., Ph.D., Massachusetts General Hospital/Harvard Medical School, Picower Institute for Learning and Memory, and Massachusetts Institute of Technology. View Media

Independence Day

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This graphic that resembles a firework was created from a picture of a fruit fly spermatid. Sigi Benjamin-Hong, Rockefeller University View Media

Fruit fly starvation leads to adipokine accumulation

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Adult Drosophila abdominal fat tissue showing cell nuclei labelled in magenta. Akhila Rajan, Fred Hutchinson Cancer Center View Media

CCP enzyme

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The enzyme CCP is found in the mitochondria of baker’s yeast. Scientists study the chemical reactions that CCP triggers, which involve a water molecule, iron, and oxygen. Protein Data Bank. View Media

Anti-tumor drug ecteinascidin 743 (ET-743) with hydrogens 02

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Ecteinascidin 743 (ET-743, brand name Yondelis), was discovered and isolated from a sea squirt, Ecteinascidia turbinata, by NIGMS grantee Kenneth Rinehart at the University of Illinois. Timothy Jamison, Massachusetts Institute of Technology View Media

Network Map

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This network map shows the overlap (green) between the long QT syndrome (yellow) and epilepsy (blue) protein-interaction neighborhoods located within the human interactome. Seth Berger, Mount Sinai School of Medicine View Media

Aspirin (with labels)

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Acetylsalicylate (bottom) is the aspirin of today. Crabtree + Company View Media