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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Polarized cells- 01

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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View Media

Insulin and protein interact in pancreatic beta cells

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A large number of proteins interact with the hormone insulin as it is produced in and secreted from the beta cells of the pancreas. William E. Balch, The Scripps Research Institute View Media

Cellular metropolis

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Like a major city, a cell teems with specialized workers that carry out its daily operations--making energy, moving proteins, or helping with other tasks. Kathryn Howell, University of Colorado Health Sciences Center View Media

Biosensors illustration

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A rendering of an activity biosensor image overlaid with a cell-centered frame of reference used for image analysis of signal transduction. Gaudenz Danuser, Harvard Medical School View Media

Arabidopsis Thaliana: Flowers Spring to Life

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This image capture shows how a single gene, STM, plays a starring role in plant development. Nathanaёl Prunet NIH Support: National Institute of General Medical Sciences View Media

Transmission electron microscopy of myelinated axons with ECM between the axons

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The extracellular matrix (ECM) is most prevalent in connective tissues but also is present between the stems (axons) of nerve cells, as shown here. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Cross section of a Drosophila melanogaster pupa

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This photograph shows a magnified view of a Drosophila melanogaster pupa in cross section. Compare this normal pupa to one that lacks an important receptor, shown in image 2759. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View Media

Cells frozen in time

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The fledgling field of X-ray microscopy lets researchers look inside whole cells rapidly frozen to capture their actions at that very moment. Here, a yeast cell buds before dividing into two. Carolyn Larabell, University of California, San Francisco, and the Lawrence Berkeley National Laboratory View Media

Cross section of a Drosophila melanogaster pupa lacking Draper

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In the absence of the engulfment receptor Draper, salivary gland cells (light blue) persist in the thorax of a developing Drosophila melanogaster pupa. Christina McPhee and Eric Baehrecke, University of Massachusetts Medical School View Media

Master clock of the mouse brain

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An image of the area of the mouse brain that serves as the 'master clock,' which houses the brain's time-keeping neurons. The nuclei of the clock cells are shown in blue. Erik Herzog, Washington University in St. Louis View Media

EM of yeast cell division

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Cell division is an incredibly coordinated process. Matthew West and Greg Odorizzi, University of Colorado View Media

Vimentin in a quail embryo

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Confocal image showing high levels of the protein vimentin (white) at the edge zone of a quail embryo. Cell nuclei are labeled green. Andrés Garcia, Georgia Tech View Media

The eye uses many layers of nerve cells to convert light into sight

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This image captures the many layers of nerve cells in the retina. The top layer (green) is made up of cells called photoreceptors that convert light into electrical signals to relay to the brain. Wei Li, National Eye Institute, National Institutes of Health View Media

Floral pattern in a mixture of two bacterial species, Acinetobacter baylyi and Escherichia coli, grown on a semi-solid agar for 48 hours (photo 2)

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Floral pattern emerging as two bacterial species, motile Acinetobacter baylyi (red) and non-motile Escherichia coli (green), are grown together for 48 hours on 1% agar surface from a sma L. Xiong et al, eLife 2020;9: e48885 View Media

Magnetic Janus particle activating a T cell

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A Janus particle being used to activate a T cell, a type of immune cell. Yan Yu, Indiana University, Bloomington. View Media

Skin cell (keratinocyte)

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This normal human skin cell was treated with a growth factor that triggered the formation of specialized protein structures that enable the cell to move. Torsten Wittmann, University of California, San Francisco View Media

Intracellular forces

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Force vectors computed from actin cytoskeleton flow. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View Media

Bacteriophage P22 capsid, detail

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Detail of a subunit of the capsid, or outer cover, of bacteriophage P22, a virus that infects the Salmonella bacteria. Dr. Wah Chiu, Baylor College of Medicine View Media

Mouse Brain Cross Section

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The brain sections are treated with fluorescent antibodies specific to a particular protein and visualized using serial electron microscopy (SEM). Anton Maximov, The Scripps Research Institute, La Jolla, CA View Media

Time-lapse video of floral pattern in a mixture of two bacterial species, Acinetobacter baylyi and Escherichia coli, grown on a semi-solid agar for 24 hours

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This time-lapse video shows the emergence of a flower-like pattern in a mixture of two bacterial species, motile Acinetobacter baylyi and non-motile Escherichia coli (green), that are gr L. Xiong et al, eLife 2020;9: e48885 View Media

HIV Capsid

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This image is a computer-generated model of the approximately 4.2 million atoms of the HIV capsid, the shell that contains the virus' genetic material. Juan R. Perilla and the Theoretical and Computational Biophysics Group, University of Illinois at Urbana-Champaign View Media

Cell-like compartments from frog eggs

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Cell-like compartments that spontaneously emerged from scrambled frog eggs, with nuclei (blue) from frog sperm. Endoplasmic reticulum (red) and microtubules (green) are also visible. Xianrui Cheng, Stanford University School of Medicine. View Media

NCMIR kidney-1

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Stained kidney tissue. The kidney is an essential organ responsible for disposing wastes from the body and for maintaining healthy ion levels in the blood. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Pathways: What is Basic Science?

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Learn about basic science, sometimes called “pure” or “fundamental” science, and how it contributes to the development of medical treatments. National Institute of General Medical Sciences View Media

Wound healing in process

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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View Media

Nucleolus subcompartments spontaneously self-assemble 4

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What looks a little like distant planets with some mysterious surface features are actually assemblies of proteins normally found in the cell's nucleolus, a small but very important protein complex lo Nilesh Vaidya, Princeton University View Media

Colony of human ES cells

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A colony of human embryonic stem cells (light blue) grows on fibroblasts (dark blue). California Institute for Regenerative Medicine View Media

Motion in the brain

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Amid a network of blood vessels and star-shaped support cells, neurons in the brain signal each other. The mists of color show the flow of important molecules like glucose and oxygen. Kim Hager and Neal Prakash, University of California, Los Angeles View Media

Drugs enter skin (with labels)

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Drugs enter different layers of skin via intramuscular, subcutaneous, or transdermal delivery methods. See image 2531 for an unlabeled version of this illustration. Crabtree + Company View Media

Lily mitosis 03

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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media

Fruit fly starvation leads to adipokine accumulation

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Adult Drosophila abdominal fat tissue showing cell nuclei labelled in magenta. Akhila Rajan, Fred Hutchinson Cancer Center View Media

Dying melanoma cells

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Melanoma (skin cancer) cells undergoing programmed cell death, also called apoptosis. This process was triggered by raising the pH of the medium that the cells were growing in. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media

Assembly of the HIV capsid

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The HIV capsid is a pear-shaped structure that is made of proteins the virus needs to mature and become infective. John Grime and Gregory Voth, The University of Chicago View Media

See how immune cell acid destroys bacterial proteins

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This animation shows the effect of exposure to hypochlorous acid, which is found in certain types of immune cells, on bacterial proteins. American Chemistry Council View Media

Motor neuron progenitors derived from human ES cells

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Motor neuron progenitors (green) were derived from human embryonic stem cells. Image and caption information courtesy of the California Institute for Regenerative Medicine. Hans Keirstead lab, University of California, Irvine, via CIRM View Media

Epithelial cell migration

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High-resolution time lapse of epithelial (skin) cell migration and wound healing. It shows an image taken every 13 seconds over the course of almost 14 minutes. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Sea urchin embryo 03

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Stereo triplet of a sea urchin embryo stained to reveal actin filaments (orange) and microtubules (blue). George von Dassow, University of Washington View Media

Lipid raft

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Researchers have learned much of what they know about membranes by constructing artificial membranes in the laboratory. Judith Stoffer View Media

Mouse retina close-up

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Keunyoung ("Christine") Kim National Center for Microscopy and Imaging Research (NCMIR) View Media

Single-cell “radios” image

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Individual cells are color-coded based on their identity and signaling activity using a protein circuit technology developed by the Coyle Lab. Scott Coyle, University of Wisconsin-Madison. View Media

Brains of sleep-deprived and well-rested fruit flies

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On top, the brain of a sleep-deprived fly glows orange because of Bruchpilot, a communication protein between brain cells. These bright orange brain areas are associated with learning. Chiara Cirelli, University of Wisconsin-Madison View Media

Mosaicism in C. elegans (Black Background)

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In the worm C. elegans, double-stranded RNA made in neurons can silence matching genes in a variety of cell types through the transport of RNA between cells. Snusha Ravikumar, Ph.D., University of Maryland, College Park, and Antony M. Jose, Ph.D., University of Maryland, College Park View Media

Early life of a protein

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This illustration represents the early life of a protein—specifically, apomyoglobin—as it is synthesized by a ribosome and emerges from the ribosomal tunnel, which contains the newly formed protein's Silvia Cavagnero, University of Wisconsin, Madison View Media

Movie of in vitro assembly of a cell-signaling pathway

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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View Media

Insulin production and fat sensing in fruit flies

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Fourteen neurons (magenta) in the adult Drosophila brain produce insulin, and fat tissue sends packets of lipids to the brain via the lipoprotein carriers (green). Akhila Rajan, Fred Hutchinson Cancer Center View Media

Yeast art depicting the New York City skyline

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This skyline of New York City was created by “printing” nanodroplets containing yeast (Saccharomyces cerevisiae) onto a large plate. Each dot is a separate yeast colony. Michael Shen, Ph.D., Jasmine Temple, Leslie Mitchell, Ph.D., and Jef Boeke, Ph.D., New York University School of Medicine; and Nick Phillips, James Chuang, Ph.D., and Jiarui Wang, Johns Hopkins University. View Media

Dopaminergic neurons derived from mouse embryonic stem cells

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These neurons are derived from mouse embryonic stem cells. Red shows cells making a protein called TH that is characteristic of the neurons that degenerate in Parkinson's disease. Yaping Sun, lab of Su Guo, University of California, San Francisco, via CIRM View Media

Video of Calling Cards in a mouse brain

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The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. NIH Director's Blog View Media

H1N1 Influenza Virus

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Related to image 6355. Dr. Rommie Amaro, University of California, San Diego View Media

Dividing cell in metaphase

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This image of a mammalian epithelial cell, captured in metaphase, was the winning image in the high- and super-resolution microscopy category of the 2012 GE Healthcare Life Sciences Cell Imaging Compe Jane Stout in the laboratory of Claire Walczak, Indiana University, GE Healthcare 2012 Cell Imaging Competition View Media