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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.

Activated mast cell surface

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A scanning electron microscope image of an activated mast cell. This image illustrates the interesting topography of the cell membrane, which is populated with receptors. Bridget Wilson, University of New Mexico View Media

Staphylococcus aureus aggregates on microstructured titanium surface

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Groups of Staphylococcus aureus bacteria (blue) attached to a microstructured titanium surface (green) that mimics an orthopedic implant used in joint replacement. Paul Stoodley, The Ohio State University. View Media

Lysosome clusters around amyloid plaques

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It's probably most people's least favorite activity, but we still need to do it--take out our trash. Otherwise our homes will get cluttered and smelly, and eventually, we'll get sick. Swetha Gowrishankar and Shawn Ferguson, Yale School of Medicine View Media

Aging book of life

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Damage to each person's genome, often called the "Book of Life," accumulates with time. Judith Stoffer View Media

Mouse colon with gut bacteria

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A section of mouse colon with gut bacteria (center, in green) residing within a protective pocket. Sarkis K. Mazmanian, California Institute of Technology View Media

Zebrafish pigment cell

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Pigment cells are cells that give skin its color. David Parichy, University of Washington View Media

Leading cells with light

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A blue laser beam turns on a protein that helps this human cancer cell move. Responding to the stimulus, the protein, called Rac1, first creates ruffles at the edge of the cell. Yi Wu, University of North Carolina View Media

Mouse liver labeled with fluorescent probe

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A mouse liver glows after being tagged with specially designed infrared-fluorescent protein (IFP). Xiaokun Shu, University of California, San Diego View Media

Tetrapolar mitosis

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This image shows an abnormal, tetrapolar mitosis. Chromosomes are highlighted pink. The cells shown are S3 tissue cultured cells from Xenopus laevis, African clawed frog. Gary Gorbsky, Oklahoma Medical Research Foundation View Media

Cell-like compartments from frog eggs 3

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Cell-like compartments that spontaneously emerged from scrambled frog eggs. Endoplasmic reticulum (red) and microtubules (green) are visible. Image created using epifluorescence microscopy. Xianrui Cheng, Stanford University School of Medicine. View Media

Crab larva eye

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Colorized scanning electron micrographs progressively zoom in on the eye of a crab larva. In the higher-resolution frames, bacteria are visible on the eye. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

Beta-galactosidase montage showing cryo-EM improvement--transparent background

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Composite image of beta-galactosidase showing how cryo-EM’s resolution has improved dramatically in recent years. Older images to the left, more recent to the right. Veronica Falconieri, Sriram Subramaniam Lab, National Cancer Institute View Media

A bundle of myelinated peripheral nerve cells (axons)

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The extracellular matrix (ECM) is most prevalent in connective tissues but also is present between the stems (axons) of nerve cells. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Induced stem cells from adult skin 01

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These cells are induced stem cells made from human adult skin cells that were genetically reprogrammed to mimic embryonic stem cells. James Thomson, University of Wisconsin-Madison View Media

Colony of human ES cells

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A colony of human embryonic stem cells (light blue) grows on fibroblasts (dark blue). California Institute for Regenerative Medicine View Media

HIV, the AIDS virus, infecting a human cell

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This human T cell (blue) is under attack by HIV (yellow), the virus that causes AIDS. Seth Pincus, Elizabeth Fischer, and Austin Athman, National Institute of Allergy and Infectious Diseases, National Institutes of Health View Media

Stretch detectors

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Muscles stretch and contract when we walk, and skin splits open and knits back together when we get a paper cut. Christopher Chen, University of Pennsylvania View Media

Z rings in bacterial division

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Lab-made liposomes contract where Z rings have gathered together and the constriction forces are greatest (arrows). Masaki Osawa, Duke University View Media

Nucleolus subcompartments spontaneously self-assemble 4

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What looks a little like distant planets with some mysterious surface features are actually assemblies of proteins normally found in the cell's nucleolus, a small but very important protein complex lo Nilesh Vaidya, Princeton University View Media

Trigonium diatom

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A Trigonium diatom imaged by a quantitative orientation-independent differential interference contrast (OI-DIC) microscope. Michael Shribak, Marine Biological Laboratory/University of Chicago. View Media

Early life of a protein

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This illustration represents the early life of a protein—specifically, apomyoglobin—as it is synthesized by a ribosome and emerges from the ribosomal tunnel, which contains the newly formed protein's Silvia Cavagnero, University of Wisconsin, Madison View Media

Confocal microscopy of perineuronal nets in the brain 2

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The photo shows a confocal microscopy image of perineuronal nets (PNNs), which are specialized extracellular matrix (ECM) structures in the brain. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media

Endothelial cell

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This image shows two components of the cytoskeleton, microtubules (green) and actin filaments (red), in an endothelial cell derived from a cow lung. Tina Weatherby Carvalho, University of Hawaii at Manoa View Media

Neural circuits in worms similar to those in humans

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Green and yellow fluorescence mark the processes and cell bodies of some C. elegans neurons. Shawn Xu, University of Michigan View Media

Peripheral nerve cell derived from ES cells

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A peripheral nerve cell made from human embryonic stem cell-derived neural crest stem cells. Stephen Dalton, University of Georgia View Media

Pathways: The Fascinating Cells of Research Organisms

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Learn how research organisms, such as fruit flies and mice, can help us understand and treat human diseases. National Institute of General Medical Sciences View Media

Fruit fly brain responds to adipokines

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Drosophila adult brain showing that an adipokine (fat hormone) generates a response from neurons (aqua) and regulates insulin-producing neurons (red).
Akhila Rajan, Fred Hutchinson Cancer Center View Media

Mitosis - metaphase

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A cell in metaphase during mitosis: The copied chromosomes align in the middle of the spindle. Judith Stoffer View Media

Intracellular forces

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Force vectors computed from actin cytoskeleton flow. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View Media

Jellyfish, viewed with ZEISS Lightsheet Z.1 microscope

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Jellyfish are especially good models for studying the evolution of embryonic tissue layers. Despite being primitive, jellyfish have a nervous system (stained green here) and musculature (red). Helena Parra, Pompeu Fabra University, Spain View Media

Cellular traffic

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Like tractor-trailers on a highway, small sacs called vesicles transport substances within cells. This image tracks the motion of vesicles in a living cell. Alexey Sharonov and Robin Hochstrasser, University of Pennsylvania View Media

Pathways: What is It? | Why Scientists Study Cells

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Learn how curiosity about the world and our cells is key to scientific discoveries. National Institute of General Medical Sciences View Media

Mouse retina

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What looks like the gossamer wings of a butterfly is actually the retina of a mouse, delicately snipped to lay flat and sparkling with fluorescent molecules. Tom Deerinck and Keunyoung (“Christine”) Kim, NCMIR View Media

Cellular polarity

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As an egg cell develops, a process called polarization controls what parts ultimately become the embryo's head and tail. This picture shows an egg of the fruit fly Drosophila. Wu-Min Deng, Florida State University View Media

Body toxins

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Body organs such as the liver and kidneys process chemicals and toxins. These "target" organs are susceptible to damage caused by these substances. Crabtree + Company View Media

Color coding of the Drosophila brain - image

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This image results from a research project to visualize which regions of the adult fruit fly (Drosophila) brain derive from each neural stem cell. Yong Wan from Charles Hansen’s lab, University of Utah. Data preparation and visualization by Masayoshi Ito in the lab of Kei Ito, University of Tokyo. View Media

Glowing bacteria make a pretty postcard

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This tropical scene, reminiscent of a postcard from Key West, is actually a petri dish containing an artistic arrangement of genetically engineered bacteria. Nathan C. Shaner, The Scintillon Institute View Media

Polarized cells- 01

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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View Media

Nucleus and rough ER

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The nucleus contains the DNA of eukaryotic cells. Judith Stoffer View Media

Magnetic Janus particle activating a T cell

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A Janus particle being used to activate a T cell, a type of immune cell. Yan Yu, Indiana University, Bloomington. View Media

Mitosis - prometaphase

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A cell in prometaphase during mitosis: The nuclear membrane breaks apart, and the spindle starts to interact with the chromosomes. Judith Stoffer View Media

Hydra 05

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Hydra magnipapillata is an invertebrate animal used as a model organism to study developmental questions, for example the formation of the body axis. Hiroshi Shimizu, National Institute of Genetics in Mishima, Japan View Media

Calling Cards in a mouse brain

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The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. Allen Yen, Lab of Joseph Dougherty, Washington University School of Medicine in St. Louis. View Media

Dividing cell

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As this cell was undergoing cell division, it was imaged with two microscopy techniques: differential interference contrast (DIC) and confocal. The DIC view appears in blue and shows the entire cell. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media

E. Coli

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Thomas Deerinck, NCMIR View Media

Tiny strands of tubulin, a protein in a cell's skeleton

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Just as our bodies rely on bones for structural support, our cells rely on a cellular skeleton. Pakorn Kanchanawong, National University of Singapore and National Heart, Lung, and Blood Institute, National Institutes of Health; and Clare Waterman, National Heart, Lung, and Blood Institute, National Institutes of Health View Media

Pigment cells in fish skin

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Pigment cells are cells that give skin its color. David Parichy, University of Washington View Media

Neutrophil-like cells migrating in a microfluidic chip

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Neutrophil-like cells (blue) in a microfluidic chip preferentially migrating toward LTB4 over fMLP. Caroline Jones, University of Texas at Dallas. View Media

See how immune cell acid destroys bacterial proteins

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This animation shows the effect of exposure to hypochlorous acid, which is found in certain types of immune cells, on bacterial proteins. American Chemistry Council View Media

Pigment cells in the fin of pearl danio

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Pigment cells are cells that give skin its color. David Parichy, University of Washington View Media