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This is a searchable collection of scientific photos, illustrations, and videos. The images and videos in this gallery are licensed under Creative Commons Attribution Non-Commercial ShareAlike 3.0. This license lets you remix, tweak, and build upon this work non-commercially, as long as you credit and license your new creations under identical terms.
STORM image of axonal cytoskeleton
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This image shows the long, branched structures (axons) of nerve cells. Xiaowei Zhuang Laboratory, Howard Hughes Medical Institute, Harvard University View MediaCentrioles anchor cilia in planaria
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Centrioles (green) anchor cilia (red), which project on the surface of pharynx cells of the freshwater planarian Schmidtea mediterranea. Juliette Azimzadeh, University of California, San Francisco View MediaCryo-ET cross-section of a rat pancreas cell
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On the left, a cross-section slice of a rat pancreas cell captured using cryo-electron tomography (cryo-ET). On the right, a 3D, color-coded version of the image highlighting cell structures. Xianjun Zhang, University of Southern California. View MediaMouse heart muscle cells
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This image shows neonatal mouse heart cells. These cells were grown in the lab on a chip that aligns the cells in a way that mimics what is normally seen in the body. Kara McCloskey lab, University of California, Merced, via CIRM View MediaHungry, hungry macrophages
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Macrophages (green) are the professional eaters of our immune system. Meghan Morrissey, University of California, Santa Barbara. View MediaSimulation of leg muscles moving
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When we walk, muscles and nerves interact in intricate ways. This simulation, which is based on data from a six-foot-tall man, shows these interactions. Chand John and Eran Guendelman, Stanford University View MediaWound healing in process
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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View MediaMyelinated axons 2
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Top view of myelinated axons in a rat spinal root. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaNeuron with labeled synapses
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In this image, recombinant probes known as FingRs (Fibronectin Intrabodies Generated by mRNA display) were expressed in a cortical neuron, where they attached fluorescent proteins to either PSD95 (gre Don Arnold and Richard Roberts, University of Southern California. View MediaMitochondrion from insect flight muscle
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This is a tomographic reconstruction of a mitochondrion from an insect flight muscle. National Center for Microscopy and Imaging Research View MediaCells keep their shape with actin filaments and microtubules
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This image shows a normal fibroblast, a type of cell that is common in connective tissue and frequently studied in research labs. James J. Faust and David G. Capco, Arizona State University View MediaWeblike sheath covering developing egg chambers in a giant grasshopper
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The lubber grasshopper, found throughout the southern United States, is frequently used in biology classes to teach students about the respiratory system of insects. Kevin Edwards, Johny Shajahan, and Doug Whitman, Illinois State University. View MediaNucleosome
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Like a strand of white pearls, DNA wraps around an assembly of special proteins called histones (colored) to form the nucleosome, a structure responsible for regulating genes and condensing DNA strand Karolin Luger, Colorado State University View MediaThree muscle fibers; the middle has a defect found in some neuromuscular diseases
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Of the three muscle fibers shown here, the one on the right and the one on the left are normal. The middle fiber is deficient a large protein called nebulin (blue). Christopher Pappas and Carol Gregorio, University of Arizona View MediaTrajectories of labeled cell receptors
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Trajectories of single molecule labeled cell surface receptors. This is an example of NIH-supported research on single-cell analysis. Gaudenz Danuser, Harvard Medical School View MediaA Growing Bacterial Biofilm
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A growing Vibrio cholerae (cholera) biofilm. Cholera bacteria form colonies called biofilms that enable them to resist antibiotic therapy within the body and other challenges to their growth. Jing Yan, Ph.D., and Bonnie Bassler, Ph.D., Department of Molecular Biology, Princeton University, Princeton, NJ. View MediaEndoplasmic reticulum abnormalities 2
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Human cells with the gene that codes for the protein FIT2 deleted. After an experimental intervention, they are expressing a nonfunctional version of FIT2, shown in green. Michel Becuwe, Harvard University. View MediaDeveloping zebrafish fin
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Originally from the waters of India, Nepal, and neighboring countries, zebrafish can now be found swimming in science labs (and home aquariums) throughout the world. Jessica Plavicki View MediaYeast cell
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A whole yeast (Saccharomyces cerevisiae) cell viewed by X-ray microscopy. Inside, the nucleus and a large vacuole (red) are visible. Carolyn Larabell, University of California, San Francisco and the Lawrence Berkeley National Laboratory View MediaGenetically identical mycobacteria respond differently to antibiotic 2
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Antibiotic resistance in microbes is a serious health concern. So researchers have turned their attention to how bacteria undo the action of some antibiotics. Bree Aldridge, Tufts University View MediaTransmission electron microscopy showing cross-section of the node of Ranvier
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Nodes of Ranvier are short gaps in the myelin sheath surrounding myelinated nerve cells (axons). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaMicrotubules in African green monkey cells
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Microtubules in African green monkey cells. Microtubules are strong, hollow fibers that provide cells with structural support. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaFat cells (red) and blood vessels (green)
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A mouse's fat cells (red) are shown surrounded by a network of blood vessels (green). Daniela Malide, National Heart, Lung, and Blood Institute, National Institutes of Health View MediaDopaminergic neurons from ES cells
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Human embryonic stem cells differentiated into dopaminergic neurons, the type that degenerate in Parkinson's disease. Image courtesy of the California Institute for Regenerative Medicine. Jeannie Liu, Lab of Jan Nolta, University of California, Davis, via CIRM View MediaFruit fly sperm cells
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Developing fruit fly spermatids require caspase activity (green) for the elimination of unwanted organelles and cytoplasm via apoptosis. Hermann Steller, Rockefeller University View MediaTime-lapse video of floral pattern in a mixture of two bacterial species, Acinetobacter baylyi and Escherichia coli, grown on a semi-solid agar for 24 hours
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This time-lapse video shows the emergence of a flower-like pattern in a mixture of two bacterial species, motile Acinetobacter baylyi and non-motile Escherichia coli (green), that are gr L. Xiong et al, eLife 2020;9: e48885 View MediaDying melanoma cells
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Melanoma (skin cancer) cells undergoing programmed cell death, also called apoptosis. This process was triggered by raising the pH of the medium that the cells were growing in. Dylan T. Burnette, Vanderbilt University School of Medicine. View MediaFluorescent E. coli bacteria
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Bioengineers were able to coax bacteria to blink in unison on microfluidic chips. They called each blinking bacterial colony a biopixel. Thousands of fluorescent E. Jeff Hasty Lab, UC San Diego View MediaLysosomes and microtubules
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Lysosomes (yellow) and detyrosinated microtubules (light blue). Lysosomes are bubblelike organelles that take in molecules and use enzymes to break them down. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaPodocytes from a chronically diseased kidney
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This scanning electron microscope (SEM) image shows podocytes--cells in the kidney that play a vital role in filtering waste from the bloodstream--from a patient with chronic kidney disease. Olga Troyanskaya, Princeton University and Matthias Kretzler, University of Michigan View MediaEpithelial cells
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This image mostly shows normal cultured epithelial cells expressing green fluorescent protein targeted to the Golgi apparatus (yellow-green) and stained for actin (magenta) and DNA (cyan). Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaSingle-cell “radios” image
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Individual cells are color-coded based on their identity and signaling activity using a protein circuit technology developed by the Coyle Lab. Scott Coyle, University of Wisconsin-Madison. View MediaChromatin in human tenocyte
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The nucleus of a degenerating human tendon cell, also known as a tenocyte. It has been color-coded based on the density of chromatin—a substance made up of DNA and proteins. Melike Lakadamyali, Perelman School of Medicine at the University of Pennsylvania. View MediaMyelinated axons 1
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Myelinated axons in a rat spinal root. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaNuclear Lamina
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The 3D single-molecule super-resolution reconstruction of the entire nuclear lamina in a HeLa cell was acquired using the TILT3D platform. Anna-Karin Gustavsson, Ph.D. View MediaInduced stem cells from adult skin 03
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The human skin cells pictured contain genetic modifications that make them pluripotent, essentially equivalent to embryonic stem cells. James Thomson, University of Wisconsin-Madison View MediaMitosis - prophase
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A cell in prophase, near the start of mitosis: In the nucleus, chromosomes condense and become visible. In the cytoplasm, the spindle forms. Judith Stoffer View MediaMouse brain slice showing nerve cells
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A 20-µm thick section of mouse midbrain. The nerve cells are transparent and weren’t stained. Michael Shribak, Marine Biological Laboratory/University of Chicago. View MediaPolarized cells- 02
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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View MediaLily mitosis 06
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View MediaVesicular shuttle model
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Animation for the vesicular shuttle model of Golgi transport. Judith Stoffer View MediaScanning electron microscopy of the ECM on the surface of a calf muscle
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This image shows the extracellular matrix (ECM) on the surface of a soleus (lower calf) muscle in light brown and blood vessels in pink. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View MediaMolecular model of freshly made Rous sarcoma virus (RSV)
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Viruses have been the foes of animals and other organisms for time immemorial. Boon Chong Goh, University of Illinois at Urbana-Champaign View MediamDia1 antibody staining-01
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Cells move forward with lamellipodia and filopodia supported by networks and bundles of actin filaments. Proper, controlled cell movement is a complex process. Rong Li and Praveen Suraneni, Stowers Institute for Medical Research View MediaG switch
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The G switch allows our bodies to respond rapidly to hormones. See images 2537 and 2538 for labeled versions of this image. Crabtree + Company View MediaFruit fly larvae brains showing tubulin
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Two fruit fly (Drosophila melanogaster) larvae brains with neurons expressing fluorescently tagged tubulin protein. Vladimir I. Gelfand, Feinberg School of Medicine, Northwestern University. View MediaDividing cells showing chromosomes and cell skeleton
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This pig cell is in the process of dividing. The chromosomes (purple) have already replicated and the duplicates are being pulled apart by fibers of the cell skeleton known as microtubules (green). Nasser Rusan, National Heart, Lung, and Blood Institute, National Institutes of Health View MediaMovie of in vitro assembly of a cell-signaling pathway
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T cells are white blood cells that are important in defending the body against bacteria, viruses and other pathogens. Xiaolei Su, HHMI Whitman Center of the Marine Biological Laboratory View MediaMisfolded proteins in mitochondria, 3-D video
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Three-dimensional image of misfolded proteins (green) within mitochondria (red). Related to image 5878. Rong Li, Department of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University View MediaHuman ES cells turn into insulin-producing cells
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Human embryonic stem cells were differentiated into cells like those found in the pancreas (blue), which give rise to insulin-producing cells (red). Eugene Brandon, ViaCyte, via CIRM View Media