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Floral pattern in a mixture of two bacterial species, Acinetobacter baylyi and Escherichia coli, grown on a semi-solid agar for 24 hours
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Floral pattern emerging as two bacterial species, motile Acinetobacter baylyi and non-motile Escherichia coli (green), are grown together for 24 hours on 0.75% agar surface from a small L. Xiong et al, eLife 2020;9: e48885 View Media
Motor neuron progenitors derived from human ES cells
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Motor neuron progenitors (green) were derived from human embryonic stem cells. Image and caption information courtesy of the California Institute for Regenerative Medicine. Hans Keirstead lab, University of California, Irvine, via CIRM View Media
NCMIR kidney-1
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Stained kidney tissue. The kidney is an essential organ responsible for disposing wastes from the body and for maintaining healthy ion levels in the blood. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Golgi
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The Golgi complex, also called the Golgi apparatus or, simply, the Golgi. Judith Stoffer View Media
Fluorescent E. coli bacteria
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Bioengineers were able to coax bacteria to blink in unison on microfluidic chips. They called each blinking bacterial colony a biopixel. Thousands of fluorescent E. Jeff Hasty Lab, UC San Diego View Media
Aldolase
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2.5Å resolution reconstruction of rabbit muscle aldolase collected on a FEI/Thermo Fisher Titan Krios with energy filter and image corrector. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media
Apoptosis reversed
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Two healthy cells (bottom, left) enter into apoptosis (bottom, center) but spring back to life after a fatal toxin is removed (bottom, right; top). Hogan Tang of the Denise Montell Lab, Johns Hopkins University School of Medicine View Media
Two mouse fibroblast cells
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Two mouse fibroblasts, one of the most common types of cells in mammalian connective tissue. They play a key role in wound healing and tissue repair. Dylan T. Burnette, Vanderbilt University School of Medicine. View Media
Bee venom toxin destroying a cell
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This video condenses 6.5 minutes into less than a minute to show how the toxin in bee venom, called melittin, destroys an animal or bacterial cell. Huey Huang, Rice University View Media
Staphylococcus aureus in the porous coating of a femoral hip stem
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Staphylococcus aureus bacteria (blue) on the porous coating of a femoral hip stem used in hip replacement surgery. Paul Stoodley, The Ohio State University. View Media
Body toxins (with labels)
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Body organs such as the liver and kidneys process chemicals and toxins. These "target" organs are susceptible to damage caused by these substances. Crabtree + Company View Media
ATP Synthase
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Atomic model of the membrane region of the mitochondrial ATP synthase built into a cryo-EM map at 3.6 Å resolution. ATP synthase is the primary producer of ATP in aerobic cells. Bridget Carragher, <a href="http://nramm.nysbc.org/">NRAMM National Resource for Automated Molecular Microscopy</a> View Media
Multivesicular bodies containing intralumenal vesicles assemble at the vacuole 3
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Collecting and transporting cellular waste and sorting it into recylable and nonrecylable pieces is a complex business in the cell. Matthew West and Greg Odorizzi, University of Colorado View Media
Kinesin moves cellular cargo
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A protein called kinesin (blue) is in charge of moving cargo around inside cells and helping them divide. Charles Sindelar, Yale University View Media
Larvae from the parasitic worm that causes schistosomiasis
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The parasitic worm that causes schistosomiasis hatches in water and grows up in a freshwater snail, as shown here. Bo Wang and Phillip A. Newmark, University of Illinois at Urbana-Champaign, 2013 FASEB BioArt winner View Media
Stem cell differentiation
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Undifferentiated embryonic stem cells cease to exist a few days after conception. In this image, ES cells are shown to differentiate into sperm, muscle fiber, hair cells, nerve cells, and cone cells. Judith Stoffer View Media
Yeast cells entering mitosis
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Yeast cells entering mitosis, also known as cell division. The green and magenta dots are two proteins that play important roles in mitosis. They show where the cells will split. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media
Video of Calling Cards in a mouse brain
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The green spots in this mouse brain are cells labeled with Calling Cards, a technology that records molecular events in brain cells as they mature. <em>NIH Director’s Blog</em>. View Media
Mouse mammary cells lacking anti-cancer protein
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Shortly after a pregnant woman gives birth, her breasts start to secrete milk. This process is triggered by hormonal and genetic cues, including the protein Elf5. Nature Cell Biology, November 2012, Volume 14 No 11 pp1113-1231 View Media
Pollen grains: male germ cells in plants and a cause of seasonal allergies
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Those of us who get sneezy and itchy-eyed every spring or fall may have pollen grains, like those shown here, to blame. Edna, Gil, and Amit Cukierman, Fox Chase Cancer Center, Philadelphia, Pa. View Media
Developing nerve cells
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These developing mouse nerve cells have a nucleus (yellow) surrounded by a cell body, with long extensions called axons and thin branching structures called dendrites. Torsten Wittmann, University of California, San Francisco View Media
Developing fruit fly nerve cord
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The glial cells (black dots) and nerve cells (brown bands) in this developing fruit fly nerve cord formed normally despite the absence of the SPITZ protein, which blocks their impending suicide. Hermann Steller, Rockefeller University View Media
Dividing yeast cells with spindle pole bodies and contractile rings
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During cell division, spindle pole bodies (glowing dots) move toward the ends of yeast cells to separate copied genetic information. Alaina Willet, Kathy Gould’s lab, Vanderbilt University. View Media
Synapses in culture
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Cultured hippocampal neurons grown on a substrate of glial cells (astrocytes). The glial cells form the pink/brown underlayment in this image. The tan threads are the neurons. National Center for Microscopy and Imaging Research View Media
Snowflake yeast 1
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Multicellular yeast called snowflake yeast that researchers created through many generations of directed evolution from unicellular yeast. William Ratcliff, Georgia Institute of Technology. View Media
Lily mitosis 06
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A light microscope image of a cell from the endosperm of an African globe lily (Scadoxus katherinae). This is one frame of a time-lapse sequence that shows cell division in action. Andrew S. Bajer, University of Oregon, Eugene View Media
Mitochondria
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Bean-shaped mitochondria are cells' power plants. These organelles have their own DNA and replicate independently. The highly folded inner membranes are the site of energy generation. Judith Stoffer View Media
Colorful cells
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Actin (purple), microtubules (yellow), and nuclei (green) are labeled in these cells by immunofluorescence. This image won first place in the Nikon 2003 Small World photo competition. Torsten Wittmann, Scripps Research Institute View Media
Neural tube development
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Proteins in the neural tissues of this zebrafish embryo direct cells to line up and form the neural tube, which will become the spinal cord and brain. Alexander Schier, Harvard University View Media
Molecular interactions at the astrocyte nuclear membrane
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These ripples of color represent the outer membrane of the nucleus inside an astrocyte, a star-shaped cell inside the brain. Katerina Akassoglou, Gladstone Institute for Neurological Disease & UCSF View Media
Host infection stimulates antibiotic resistance
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This illustration shows pathogenic bacteria behave like a Trojan horse: switching from antibiotic susceptibility to resistance during infection. View Media
Pigment cells in fish skin
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Pigment cells are cells that give skin its color. David Parichy, University of Washington View Media
Bacteriophage P22 capsid
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Cryo-electron microscopy (cryo-EM) has the power to capture details of proteins and other small biological structures at the molecular level. This image shows proteins in the capsid, or outer co Dr. Wah Chiu, Baylor College of Medicine View Media
Mouse heart fibroblasts
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This image shows mouse fetal heart fibroblast cells. The muscle protein actin is stained red, and the cell nuclei are stained blue. Kara McCloskey lab, University of California, Merced, via CIRM View Media
Cell cycle (with labels)
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Cells progress through a cycle that consists of phases for growth (G1, S, and G2) and division (M). Cells become quiescent when they exit this cycle (G0). Crabtree + Company View Media
Cellular metropolis
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Like a major city, a cell teems with specialized workers that carry out its daily operations--making energy, moving proteins, or helping with other tasks. Kathryn Howell, University of Colorado Health Sciences Center View Media
Microtubule dynamics in real time
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Cytoplasmic linker protein (CLIP)-170 is a microtubule plus-end-tracking protein that regulates microtubule dynamics and links microtubule ends to different intracellular structures. Gary Borisy, Marine Biology Laboratory View Media
Human retinal organoid
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A replica of a human retina grown from stem cells. Kevin Eliceiri, University of Wisconsin-Madison. View Media
NCMIR human spinal nerve
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Spinal nerves are part of the peripheral nervous system. They run within the spinal column to carry nerve signals to and from all parts of the body. Tom Deerinck, National Center for Microscopy and Imaging Research (NCMIR) View Media
Protein map
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Network diagram showing a map of protein-protein interactions in a yeast (Saccharomyces cerevisiae) cell. This cluster includes 78 percent of the proteins in the yeast proteome. Hawoong Jeong, KAIST, Korea View Media
Wound healing in process
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Wound healing requires the action of stem cells. Hermann Steller, Rockefeller University View Media
Fluorescence in situ hybridization (FISH) in mouse ES cells shows DNA interactions
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Researchers used fluorescence in situ hybridization (FISH) to confirm the presence of long range DNA-DNA interactions in mouse embryonic stem cells. Kathrin Plath, University of California, Los Angeles View Media
Mouse colon with gut bacteria
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A section of mouse colon with gut bacteria (center, in green) residing within a protective pocket. Sarkis K. Mazmanian, California Institute of Technology View Media
Dense tubular matrices in the peripheral endoplasmic reticulum (ER) 1
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Superresolution microscopy work on endoplasmic reticulum (ER) in the peripheral areas of the cell showing details of the structure and arrangement in a complex web of tubes. Jennifer Lippincott-Schwartz, Howard Hughes Medical Institute Janelia Research Campus, Virginia View Media
Dynamin structure
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When a molecule arrives at a cell's outer membrane, the membrane creates a pouch around the molecule that protrudes inward. Josh Chappie, National Institute of Diabetes and Digestive and Kidney Diseases, NIH View Media
Trypanosoma brucei, the cause of sleeping sickness
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Trypanosoma brucei is a single-cell parasite that causes sleeping sickness in humans. Michael Rout, Rockefeller University View Media
STORM image of axonal cytoskeleton
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This image shows the long, branched structures (axons) of nerve cells. Xiaowei Zhuang Laboratory, Howard Hughes Medical Institute, Harvard University View Media
Human Adenovirus
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The cryo-EM structure of human adenovirus D26 (HAdV-D26) at near atomic resolution (3.7 Å), determined in collaboration with the NRAMM facility*. National Resource for Automated Molecular Microscopy http://nramm.nysbc.org/nramm-images/ Source: Bridget Carragher View Media
Neurons from human ES cells 02
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These neurons were derived from human embryonic stem cells. The neural cell bodies with axonal projections are visible in red, and the nuclei in blue. Xianmin Zeng lab, Buck Institute for Age Research, via CIRM View Media
