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PSI:Biology Network

Note: This is an archived page that is not updated.

The Protein Structure Initiative ended 7/1/2015.

NIGMS supported the following research centers during the Protein Structure Initiative:Biology phase. For more information about the centers and projects listed below, visit the PSI:Biology Structural Biology Knowledgebase Link to external Web site.

PSI:Biology Centers for High-Throughput Structure Determination
PSI:Biology Centers for Membrane Protein Structure Determination
PSI:Biology Consortia for High-Throughput-Enabled Structural Biology Partnerships
PSI:Biology Resource Centers

PSI:Biology Network


PSI:Biology Network
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PSI:Biology Centers for High-Throughput Structure Determination

Joint Center for Structural Genomics
Principal investigator: Ian A. Wilson, D.Phil., Scripps Research Institute
http://www.jcsg.org Link to external Web site

Midwest Center for Structural Genomics
Principal investigator: Andrzej Joachimiak, Ph.D., University of Chicago
http://www.mcsg.anl.gov Link to external Web site

New York Structural Genomics Research Consortium
Principal investigator: Steven Almo, Ph.D., Albert Einstein College of Medicine of Yeshiva University
http://www.nysgrc.org Link to external Web site

Northeast Structural Genomics Consortium
Principal investigator: Gaetano T. Montelione, Ph.D., Rutgers University
http://www.nesg.org Link to external Web site

PSI:Biology Centers for Membrane Protein Structure Determination

Center for Membrane Proteins in Infectious Diseases
Principal investigator: Petra Fromme, Ph.D., Arizona State University

Center for Structure of Membrane Proteins
Principal investigator: Robert M. Stroud, Ph.D., University of California, San Francisco
http://csmp.ucsf.edu Link to external Web site

Center for the X-ray Structure Determination of Human Transporters
Principal investigators: Douglas C. Rees, Ph.D., California Institute of Technology; Geoffrey A. Chang, Ph.D., Scripps Research Institute; Michael H.B. Stowell, Ph.D., University of Colorado

GPCR Network
Principal investigator: Raymond C. Stevens, Ph.D., Scripps Research Institute
http://cmpd.scripps.edu/gpcr_network.htm Link to external Web site

Membrane Protein Structural Biology Consortium
Principal investigators: Michael G. Malkowski, Ph.D., Hauptman Woodward Medical Institute; Mark E. Dumont, Ph.D., University of Rochester; Michael Wiener, Ph.D., University of Virginia
http://mpsbc.org Link to external Web site

Membrane Protein Structures by Solution NMR
Principal investigator: James J. Chou, Ph.D., Harvard University Medical School

New York Consortium on Membrane Protein Structure
Principal investigator: Wayne A. Hendrickson, Ph.D., New York Structural Biology Center

Transcontinental EM Initiative for Membrane Protein Structure
Principal investigator: David L. Stokes, Ph.D., New York Structural Biology Center
http://temimps.nysbc.org Link to external Web site

Transmembrane Protein Center
Principal investigator: Brian G. Fox, Ph.D., University of Wisconsin-Madison
http://www.uwmembraneproteins.org Link to external Web site

PSI:Biology Consortia for High-Throughput-Enabled Structural Biology Partnerships

Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions
Principal investigators: Robert Liddington, Ph.D., Sanford-Burnham Medical Research Institute; William James Nelson, Ph.D., Stanford University

Atoms-to-Animals: The Immune Function Network
Principal investigator: Arturo Casadevall, M.D., Ph.D., Albert Einstein College of Medicine of Yeshiva University

Chaperone-Enabled Studies of Epigenetic Regulation Enzymes
Principal investigator: Anthony A. Kossiakoff, Ph.D., University of Chicago

Enzyme Discovery for Natural Product Biosynthesis
Principal investigator: George Phillips, Ph.D., Rice University
http://www.natprobio.org/ Link to external Web site

Mitochondrial Protein Partnership
Principal investigator: John L. Markley, Ph.D., University of Wisconsin-Madison
http://www.mitoproteins.org Link to external Web site

Program for Characterization of Secreted Effector Proteins
Principal investigator: Joshua N. Adkins, Ph.D., Battelle Pacific Northwest Laboratories

Nucleocytoplasmic Transport: A Target for Cellular Control
Principal investigator: Michael Rout, Ph.D., Rockefeller University

Ribonucleoprotein Complexes Regulating T-Cell Activation
Principal investigators: James R. Williamson, Ph.D., Scripps Research Institute; Daniel R. Salomon, M.D., Scripps Research Institute

Structural Basis of Protein Homeostasis 
Principal investigator: Peter Walter, Ph.D., University of California, San Francisco

Structural Features of the Nuclear Receptor Signaling Code
Principal investigator: Kendall Nettles, Ph.D., The Scripps Research Institute, Florida

Structure, Dynamics and Activation Mechanisms of Chemokine Receptors
Principal investigators: Tracy M. Handel, Ph.D., University of California, San Diego; Ruben A. Abagyan, Ph.D., University of California, San Diego

Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes
Principal investigator: Celia Goulding, Ph.D., University of California, Irvine

Structure-Function Studies of Tight Junction Membrane Proteins
Principal investigator: Alan S. Yu, M.D., University of Southern California

Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors
Principal investigator: James C. Sacchettini, Ph.D., Texas A&M University

Structures of Protein Complexes Regulating Transcription in Embryonic Stem Cells
Principal investigator: Robert J. Fletterick, Ph.D., University of California, San Francisco

PSI:Biology Resource Centers

Materials Repository
Principal investigator: Josh Labaer, Ph.D., Arizona State University
http://psimr.asu.edu Link to external Web site

Structural Biology Knowledgebase
Principal investigator: Helen Berman, Ph.D., Rutgers University
http://www.sbkb.org Link to external Web site

This page last reviewed on January 06, 2016