Skip Over Navigation Links


Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the we​bsite may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit Updates regarding government operating status and resumption of normal operations can be found at

PSI:Biology (program ended 7/1/2015)

Note: This is an archived page that is not updated.

Protein Structure Initiative (PSI): BiologyDuring the current PSI:Biology phase, highly organized networks of investigators are applying the paradigm of high-throughput structure determination, which was successfully developed during the earlier phases of the PSI, to study a broad range of important biological and biomedical problems. The initiative is making resources for high-throughput structure determination available to a larger community of scientists than has been engaged to date. The majority of targets for structure determination are defined through consortium partnership arrangements and an open, on-going community nomination process. Additional targets are defined through biological theme projects of the structure determination centers.

Background Information

Learn more about the goals of PSI:Biology

PSI:Biology Network

View the organizational structure of the PSI:Biology network and how the different components interact.

This page last reviewed on December 31, 2015