Cryogenic tanks filled with liquid nitrogen and millions of vials of frozen cells. Credit: Coriell Institute for Medical Research.
The NIGMS Human Genetic Cell Repository is a collection of well-characterized, high-quality human cells for use in biomedical research. Established by NIGMS in 1972 and housed at the Coriell Institute for Medical Research in Camden, New Jersey, the repository contains more than 11,300 cell lines and 5,700 DNA samples derived from them. The specimens, which are equally divided between those from males and those from females, were acquired from individuals with inherited diseases, apparently healthy individuals and individuals of diverse geographic origins. Almost 900 diseases and 40-plus population groups are currently represented in the repository. It also includes a collection of induced pluripotent stem (iPS) cell lines that carry disease gene mutations or are normal control iPS cell lines.
The NIGMS cell repository Web site includes a list of collections, ordering information, sample submission instructions and frequently asked questions.