Research to Understand and Inform Interventions that Promote the Research Careers of Individuals in Biomedical Sciences (R01/R35)

NIGMS has long encouraged the use of evidence-informed practices to improve research education, training, and career development. The institute recognizes that there is need for more hypothesis-driven research to test biomedical training, mentoring and networking interventions for efficacy and replicability across career stages and at a range of institution types. The purpose of ’Research on Interventions’ research program is to support research that will enhance the evidence base for effective, high-impact, scalable interventions, and improve our understanding of the factors contributing to the advancement of individuals pursuing biomedical research careers.

NIGMS strives to ensure that future generations of researchers will be drawn from the entire pool of talented individuals, bringing different aptitudes, perspectives, interests, and experiences to address complex scientific problems. Accordingly, NIGMS encourages applications designed to understand and inform interventions that promote the research careers of individuals from underrepresented groups (see NIH’s Interest in Diversity).

While a broad range of topics are encouraged, NIGMS has published a Notice of Special Interest (NOT-GM-21-033) to inform applicants of potential topic areas to address the impacts of structural racism and discrimination on biomedical career progression and the biomedical research enterprise. Additionally, the Office of Research on Women's Health has published a notice (NOT-OD-21-068) designed to change the culture to mitigate or eliminate sexual harassment in the biomedical research enterprise. 

Projects are expected to include the use of robust experimental designs, including randomized control trial approaches, case controls, matched pair design or other rigorous designs appropriate to the research questions. The research results are expected to move beyond participant satisfaction, self-reporting of perceived skills gained, or self-reporting of effectiveness. Accordingly, the training, mentoring, and networking interventions are to be centered not only on psychosocial factors, but also on outcomes so that the results will inform the biomedical community regarding the factors and mechanisms that are most likely to influence and foster a sustained career in the biomedical research workforce.

Investigators interested in addressing these objectives may apply in response to PAR-19-295, Research to Understand and Inform Interventions that Promote the Research Careers of Individuals in the Biomedical Sciences (R01 - Clinical Trial Not Allowed). This research may also be supported by the Maximizing Investigators’ Research Award (MIRA) R35 grant, which will support both established investigators and early stage investigators.​

For additional information about the Research on Interventions program, contact Dr. Michael Sesma or Dr. Sydella Blatch​.

Research on Interventions Awardees