Investigator-Initiated Research Grants

These grants support investigator-initiated projects in basic biomedical research. Projects funded under these grants could lead to new or improved technologies, including reagents, instruments, devices and methodologies, algorithms, or software that can be utilized in a broad range of biomedical research.

Funding Mechanisms

  • Focused Technology Development Research Grants (R01) support research that may involve a concept, design, fabrication, and/or test of technologies, with the overall objective of leading to more powerful and useful tools for biomedical research. The application is expected to include preliminary data that support the proposed project.

  • Exploratory Technology Development Research Grants (R21) support research on novel concepts that have not yet been tested for feasibility. These grants reward high-risk or novel approaches with potential for significant impact. This NIGMS R21 mechanism must not have preliminary data and cannot be renewed.

  • Maximizing Investigator's Research Award (MIRA) (R35) provides support for a research program in an investigator's laboratory, including technology development, that falls within the mission of NIGMS. MIRA grants are generally for five years and can provide investigators with greater stability and flexibility.

  • Academic Research Enhancement Awards (AREA) (R15) supports biomedical research in educational institutions that provide baccalaureate training for a significant number of the nation's research scientists but have not been major recipients of NIH support. This award enables qualified scientists to receive support for up to 3 years for small-scale research projects.

  • Support for Research Excellence (SURE) Program (R16) develops and sustains research excellence of faculty investigators and provides students with research opportunities while enriching the research environment at institutions that award baccalaureates and/or graduate degrees in the biomedical sciences. Eligibility: (I) 25% or more of undergraduate students are supported by Pell grants or (ii) accredited medical/health professional school with a historical mission statement that explicitly states that it was founded to educate students from nationally underrepresented​ backgrounds.

  • Investigator-Initiated Research Grants (R01) support a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s) that fall within the mission of NIGMS.

For more information about biomedical technology program support for investigator-initiated research grants, contact:

Dr. Dorothy Beckett
Division of Biophysics, Biomedical Technology, and Computational Biosciences
National Institute of General Medical Sciences
National Institutes of Health
45 Center Drive MSC 6200
Bethesda, MD 20892-6200