AnnouncementOctober 1, 2008
Libraries of small molecules are a crucial source of potential new drugs and research tools. Yet existing collections—and the techniques needed to generate them—fail to meet all the needs of pharmaceutical and biomedical scientists. Continuing its commitment to address this problem, the National Institute of General Medical Sciences (NIGMS) announces support for five Centers of Excellence in Chemical Methodologies and Library Development (CMLD).
With this announcement, NIGMS is funding one new center and renewing support for its four existing CMLD centers. Over their 5-year lifetimes, these five centers are expected to total more than $48 million.
Each CMLD center will develop cutting-edge technologies to generate, analyze, and optimize chemical libraries and will synthesize thousands of novel chemical entities using high-throughput techniques.
Central to the CMLD effort is making the new methods and resources broadly available for biomedical research and drug discovery. To facilitate this, each CMLD center must collaborate with biologists to determine the physiological activities of the new molecules.
The CMLD centers will also feed their chemical libraries directly into the NIH Molecular Libraries Roadmap Initiative, which will screen them in its search for chemical probes to study biology.
Each CMLD center is a collaborative effort involving teams of researchers. The five centers are:
For more details about the CMLD projects launched in 2002 and 2003, see
NIGMS Center Grants Will Spice Up Chemical LibrariesOctober 10, 2002
NIGMS Chemistry Center Grants To Expand Drug Discovery ToolkitOctober 1, 2003
For information about the awards, see /Research/FeaturedPrograms/CMLD/ or contact Alisa Machalek in the NIGMS Office of Communications and Public Liaison at (301) 496-7301 or firstname.lastname@example.org.
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8/9/2018 4:46 PM
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