The Industry Liaison Group met with members of the Pharmacogenetics Research Network on the evening of March 11, 2002 at Stanford University. At their meeting, the group considered the newest release of PharmGKB, and discussed the "levels of evidence" model for relating phenotype to genotype information as four categories: molecular and cellular assays, pharmacokinetics, pharmacodynamics, and clinical outcomes.
There was also a discussion of the current terminology used to categorize samples derived from clinical pharmacogenetic studies, including areas where standards are not yet set. Additionally, the joint group considered the issues underlying communication of the importance of pharmacogenetics to the public and the press, and the distinction between research studies and current medical practice. They agreed that this is a challenging area, where the network's goal is to educate and yet not endorse.
The meeting included informal exchanges around the topic of scientific opportunities in the field for academia and for industry. The evening concluded with the attendees looking forward to attending the public meeting the next day, March 12th, in Fairchild Auditorium at Stanford University. A
summary of the presentations [PDF] at that day's meeting.
Donald C. Anderson, M.D.
7000 Portage Road
7272-24-113Kalamazoo, Michigan 49001-0199
Wayne H. Anderson, Ph.D.*GlaxoSmithKline
Building 5, Room 5808
P.O. Box 13398Research Triangle Park, North Carolina 27709
Lee E. Babiss, Ph.D. **Hoffmann-La Roche Inc.
Preclinical Research and Development
340 Kingsland Street
Nutley, New Jersey 07110
Andrew Joseph Dorner, Ph.D.*,**
2 Burtt Road
Andover, Massachusetts 01810
Daniel Farkas, Ph.D.*, **Motorola Life Sciences
757 South Raymond AvenuePasadena, California 91105
Larry Gelbert, Ph.D.*, **Research Scientist Research Technologies and Proteins
Eli Lilly and Company
Lilly Corporate Center
Indianapolis, Indiana 46285
Penelope K. Manasco, M.D**First Genetic TrustThree Parkway North CenterDeerfield, IL 60015
Glenn A. Miller, Ph.D.*Genzyme Corporation
1 Mountain Road
Framingham, Massachusetts 01701
Brian B. Spear, Ph.D.
Department 424, AP6A-1
100 Abbott Park Road
Abbott Park, Illinois 60064-6008
Vincent P. Stanton Jr., M.D.
60 Hampshire Street
Cambridge, Massachusetts 02139
NIGMS Program Director
Rochelle M. Long, Ph.D.National Institute of General Medical SciencesNational Institutes of HealthNatcher Building, Room 2AS.49G45 Center Drive MSC 6200Bethesda, Maryland 20892-6200Tel: (301) 594-3827Fax: (301) 480-2802Email:
Gillian R. Woollett, M.A., D.Phil.Pharmaceutical Research and Manufacturers of America
110 Fifteenth Street, NWWashington, D.C. 20005
* New members in 2002
** Not in attendance
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