The legacy community-wide scientific resources program provides supports the existing resources for maintenance activities only. NIGMS defines a resource as a non-hypothesis-driven activity to provide data, materials, tools or services that are essential to making the most timely, high quality and cost-efficient progress in a field, that has great potential for having high value to a community of researchers that the Institute supports.
Mary Ann Wu, Ph.D. Program Director Division of Biophysics, Biomedical Technology, and Computational Biosciences National Institute of General Medical Sciences National Institutes of Health 45 Center Drive MSC 6200 Bethesda, MD 20892-6200
R24 Grant Number: R24GM136766Principal Investigator: Michael L. Gross, Ph.D. The Biomedical Mass Spectrometry (MS) Resource develops novel MS-based solutions to analytical challenges, and provides service, collaboration, and training for MS-based characterization, identification and quantification of all biomolecular classes extracted from in vitro and in vivo model systems.
R24 Grant Number: R24GM136986Principal Investigator: Rob S. MacLeod, Ph.D., Christopher R. Johnson, Ph.D., Ross T. Whitaker, Ph.D. The CIBC Legacy Resource provides open-source software tools for biomedical image-based modeling, biomedical simulation and estimation, and the visualization of biomedical data.
R24 Grant Number: R24GM136984Principal Investigator: Robert J. Woods GLYCAM-Web is dedicated to simplifying the prediction of three-dimensional structures of carbohydrates and macromolecular structures involving carbohydrates by providing access to online prediction tools and libraries.
R24 Grant Number: R24GM134210Principal Investigator: Catherine E. Costello, Ph.D. The Mass Spectometry Resource focuses on the needs of glycobiology for detailed structural elucidations and the profiling of complex mixtures of glycans. Reference data that illuminates glycan fragmentation pathways using multiple dissociation methods is compiled and deposited into public databases; new, user-friendly bioinformatics tools that the Resource has created for glycan analysis will be completed, tested and shared. Protocols and sets of reference data for Ion mobility-tandem mass spectrometry are compiled for the analysis of glycans and complex peptide mixtures, for characterization of noncovalent complexes, and for evaluation of new ExD cell designs being constructed by a small industry collaborator.
R24 Grant Number: R24GM137200Principal Investigator: Mark H. Ellisman, Ph.D. NCMIR provides services in computer-aided, advanced microscopy for the acquisition of structural and functional data in the dimensional range of 1 nm to 100 um, which encompasses macromolecules, subcellular structures and cells as a fee-for-service legacy resource, and disseminates microscopy probes and reagents as well as other established tools.
