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AIDS-Related Structural Biology Program

For more than 25 years, NIGMS has supported the structural characterization of human immunodeficiency virus (HIV) enzymes and viral proteins. This support has been instrumental in the development of crucial drugs for antiretroviral therapy such as protease inhibitors. NIGMS continues to support further characterization of viral proteins as well as cellular and viral complexes. These complexes represent the fundamental interactions between the virus and its host target cell and, as such, represent potential new targets for therapeutic development.

Specialized Centers for HIV/AIDS-Related Structural Biology
Specialized Centers for the Determination of Structures and HIV/Host Complexes Center for RNA Studies (CRNA) Center for the Structural Biology of Cellular Host Elements in Egress, Trafficking, and Assembly of HIV (CHEETAH)HIV Accessory and Regulatory Complexes (HARC) CenterHIV Interaction and Viral Evolution (HIVE) CenterPittsburgh Center for HIV Protein Interactions (PCHPI) 

This page last reviewed on May 25, 2016