The National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, has invested $16.4 million of American Recovery and Reinvestment Act (Recovery Act) funds to jump-start a range of research projects that address critical gaps in the basic biomedical and behavioral sciences.
The new two-year awards, which are called Challenge Grants, focus on overcoming specific scientific and technological challenges in areas of interest to NIGMS. These include stem cells, molecular imaging, synthetic biology, drug discovery, green chemistry, behavioral research and research training.
The Recovery Act awards support 19 projects in 12 states, enabling scientists to explore important research questions while stimulating their local economies through job creation, training and purchasing of new equipment.
“The basic research supported by NIGMS lays a foundation for disease diagnosis, treatment and prevention,” said NIGMS Director Jeremy M. Berg, Ph.D. “These Challenge Grants, made possible by the Recovery Act, enable us to capitalize on scientific opportunities in a range of our mission areas by speeding progress toward new tools, methods and knowledge.”
The NIGMS Challenge Grants will enable, for example:
Other NIGMS Challenge Grant projects include:
Hierarchical Spatial Process Models for Estimating and Predicting Health Effects, $610,295Sudipto Banerjee, University of Minnesota-Twin Cities, Minneapolis
Novel Approaches to Structure/Function Analyses of Heparan Sulfate in Vivo, $844,027Hannes Erich Buelow, Albert Einstein College of Medicine, New York City
An Assessment of Multimodal Physics Lab Intervention Efficacy in STEM Education, $809,695Kwan H. Cheng and Beth Thacker, Texas Tech University, Lubbock
Neurogenomics of Social Behavior: Songbird Models, $979,180David F. Clayton, University of Illinois at Urbana-Champaign
Capture of Ubiquitin Conjugation and Deconjugation Enzyme Substrates, $674,966Robert Cohen, Colorado State University, Fort Collins
Nuclear Organization in Stem and Differentiated Cells, $775,000Victor G. Corces, Emory University, Atlanta
Riboswitch Design Principles: Interplay Between Switching, Ligand Binding and Folding, $938,041Scott Patrick Hennelly and Kevin Y. Sanbonmatsu, Los Alamos National Laboratory, Los Alamos, N.M.
Enzyme-Mediated Synthesis of Functionalized Terpene Structures, $1,000,000Jay D. Keasling, University of California, Berkeley
Sub-Wavelength Imaging of Intracellular Metal Ions, $860,237Joseph R. Lakowicz, University of Maryland, Baltimore
Biochemical Studies of Drosophila RNA-Induced Silencing Complex, $767,805Qinghua Liu, University of Texas Southwestern Medical Center at Dallas
Structure-Function Studies of Modular Human Mediator Coactivator Complex, $943,256Robert G. Roeder, Rockefeller University, New York City
Suspended Bilayers: New Technology to Study the Dynamics of Membrane Structure and Function, $969,272 James E. Rothman, Yale University, New Haven, Conn.
Reading the Histone Code: The Nanoscale Morphology of Epigenomic Histone Modifications, $911,875M. Mitchell Smith, University of Virginia, Charlottesville
Molecular Platforms for the Development of Intelligent Therapeutics Targeted to Diseased Cells, $999,892Christina D. Smolke, Stanford University, Stanford, Calif.
A New Paradigm for Biomolecular Simulations, $903,718Donald G. Truhlar and Jiali Gao, University of Minnesota-Twin Cities, Minneapolis
Posttranscriptional Regulation of Gene Expression in Eukaryotes, $991,518Karsten Weis, University of California, Berkeley
In addition to these awards, the NIH Office of the Director is supporting 15 Challenge Grants closely aligned with the NIGMS mission.
For project details, go to http://projectreporter.nih.gov/reporter.cfm, check the box that says “Show only projects supported by NIH Recovery Act funds” and enter the name of the scientist in the Principal Investigator field.
NIGMS is a part of NIH that supports basic research to increase our understanding of life processes and lay the foundation for advances in disease diagnosis, treatment and prevention. For more information on the Institute's research and training programs, see http://www.nigms.nih.gov.
The National Institutes of Health (NIH) — The Nation's Medical Research Agency — includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. It is the primary Federal agency for conducting and supporting basic, clinical, and translational medical research, and it investigates the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.
The activities described in this release are being funded through the American Recovery and Reinvestment Act (ARRA). More information about NIH’s ARRA grant funding opportunities can be found at http://grants.nih.gov/recovery. To track the progress of HHS activities funded through the ARRA, visit https://www.hhs.gov . To track all federal funds provided through the ARRA, visit www.recovery.gov.
This page last reviewed on
8/9/2018 4:48 PM
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