National Institutes of Health
Basic Discoveries for Better Health
Selected news articles and other coverage related to NIGMS’ Protein Structure Initiative, an effort aimed at dramatically reducing the costs and lessening the time it takes to determine three-dimensional protein structures.
The next phase of the PSI enlists biologists to help crack tough protein structure and function problems.
Researchers involved in the Protein Structure Initiative are uncovering the three-dimensional shapes of proteins to speed advances in many areas of biomedicine.
NIGMS will launch PSI:Biology to support research partnerships between biologists and high-throughput structure determination centers to solve biological problems with knowledge gained from earlier PSI efforts.
Advances led by PSI-supported scientists have had a major technological impact on structural genomics efforts.
Researchers supported by the PSI and the NIGMS Small Business Innovation Research Program have developed a miniature synchrotron that could transform many fields of biomedical research.
Two papers show that X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy can serve complementary roles in the determination of protein structures.
NIGMS Director Jeremy M. Berg and PSI Director John Norvell highlight the technical achievements made during the PSI pilot phase and goals for the current PSI production phase.
As NIH plans to extend its high-speed structural biology program for another 5 years, researchers remain divided on how best to allocate its shrinking budget.
The Protein Structure Initiative has already come up with one surprise: Proteins apparently come in a limited variety of shapes.