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NIGMS-Supported Nobelists

Fact Sheet: NIGMS-Supported Nobelists

Crossword Puzzle: Test Your Nobel Knowledge | Accessible Version

Name Year Field Citation Announcement
William E. Moerner 2014 Chemistry For the development of super-resolved fluorescence microscopy http://www.nigms.nih.gov/News/Results/
pages/20141008.aspx
Martin Karplus, Michael Levitt & Arieh Warshel 2013 Chemistry For the development of multiscale models for complex chemical systems http://www.nigms.nih.gov/News/Results/
pages/20131024
James E. Rothman & Randy W. Schekman 2013 Physiology
or
Medicine
For their discoveries of machinery regulating vesicle traffic, a major transport system in our cells http://www.nigms.nih.gov/News/Results/
pages/20131024
Brian K. Kobilka 2012 Chemistry For studies of G-protein-coupled receptors http://www.nigms.nih.gov/News/Results/
pages/20121010.htm
 
Ei-ichi Negishi 2010 Chemistry For palladium-catalyzed cross couplings in organic synthesis http://www.nigms.nih.gov/News/Results/
pages/nobelprize_101006.htm
Venkatraman Ramakrishnan, Thomas A. Steitz & Ada E. Yonath 2009 Chemistry For studies of the structure and function of the ribosome http://www.nigms.nih.gov/News/Results/
pages/nobel_20091007a.htm
Elizabeth H. Blackburn, Carol W. Greider & Jack W. Szostak 2009 Physiology
or
Medicine
For the discovery of how chromosomes are protected by telomeres and the enzyme telomerase http://www.nigms.nih.gov/News/Results/
pages/nobel20091005.htm
Osamu Shimomura, Martin Chalfie & Roger Y. Tsien 2008 Chemistry For the discovery and development of the green fluorescent protein, GFP http://www.nigms.nih.gov/News/Results/
pages/nobel_chemistry20081008.htm
Mario R. Capecchi & Oliver Smithies 2007 Physiology
or
Medicine
For the discovery of principles for introducing specific gene modifications in mice by the use of embryonic stem cells http://www.nigms.nih.gov/News/Results/
pages/10082007c.htm
Roger D. Kornberg 2006 Chemistry For his studies of the molecular basis of eukaryotic transcription http://www.nigms.nih.gov/News/Results/
pages/10042006_nobel2.htm
Andrew Z. Fire & Craig C. Mello 2006 Physiology
or
Medicine
For the discovery of RNA interference—gene silencing by double-stranded RNA http://www.nigms.nih.gov/News/Nobels/
pages/10022006_nobel2.htm
Robert H. Grubbs & Richard R. Schrock 2005 Chemistry For the development of the metathesis method in organic synthesis [a chemical reaction for making carbon-carbon bonds] http://www.nih.gov/news/pr/oct2005/od-05.htm
Avram Hershko & Irwin Rose 2004 Chemistry For the discovery of ubiquitin-mediated protein degradation http://www.nih.gov/news/pr/oct2004/od-06.htm
Paul C. Lauterbur 2003 Physiology
or
Medicine
For discoveries concerning magnetic resonance imaging http://www.nigms.nih.gov/News/Results/
pages/Nobel_Medicine_2003.htm
Roderick MacKinnon 2003 Chemistry For discoveries concerning channels in cell membranes [specifically, for structural and mechanistic studies of ion channels] http://www.nigms.nih.gov/News/Results/
pages/Nobel_Chemistry_2003.htm
H. Robert Horvitz 2002 Physiology
or
Medicine
For discoveries concerning genetic regulation of organ development and programmed cell death http://www.nigms.nih.gov/News/Results/
pages/NIHGranteeHRobertHorvitzWins.htm
John B. Fenn 2002 Chemistry For the development of methods for identification and structure analyses of biological macromolecules [specifically, for techniquesin mass spectrometry] http://www.nigms.nih.gov/News/Results/
pages/NIGMSGranteeJohnFennWins
NobelPrize.htm
Leland H. Hartwell 2001 Physiology
or
Medicine
For discoveries of key regulators of the cell cycle http://www.nigms.nih.gov/News/Results/
pages/NIHGranteeLelandHartwellWinsNobel
PrizeBreakthroughsUnderstanding.htm
K. Barry Sharpless 2001 Chemistry For work on chirally catalyzed oxidation reactions [a technique to selectively control the outcome of chemical reactions] http://www.nigms.nih.gov/News/Results/
pages/NIGMSGranteeKBarrySharplessWins
NobelPrizeAdvances.htm
Eric R. Kandel 2000 Physiology
or
Medicine
For discoveries concerning signal transduction in the nervous system http://www.nih.gov/news/pr/oct2000/od-09.htm
Günter Blobel 1999 Physiology
or
Medicine
For the discovery that proteins have intrinsic signals that govern their transport and localization in the cell http://www.nih.gov/news/pr/oct99/nigms-11.htm
John A. Pople 1998 Chemistry For development of computational methods in quantum chemistry http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1998/press.html
Link to external Web site
Paul D. Boyer 1997 Chemistry For elucidation of the enzymatic mechanism underlying the synthesis of adenosine triphosphate (ATP) http://www.nih.gov/news/pr/oct97/nigms-15.htm
Stanley B. Prusiner 1997 Physiology
or
Medicine
For discovery of prions—a new biological principle of infection http://www.nih.gov/news/pr/oct97/ninds-06.htm
Edward B. Lewis 1995 Physiology
or
Medicine
For discoveries concerning the genetic control of early embryonic development http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1995/press.html
Link to external Web site
George A. Olah 1994 Chemistry For contributions to carbocation chemistry http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1994/press.html
Link to external Web site
Alfred G. Gilman 1994 Physiology
or
Medicine
For discovery of G-proteins and the role of these proteins in signal transduction in cells http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1994/press.html
Link to external Web site
Kary B. Mullis 1993 Chemistry For contributions to the developments of methods within DNA- based chemistry [specifically, for his invention of the polymerasechain reaction (PCR) method] http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1993/press.html
Link to external Web site
Michael Smith 1993 Chemistry For contributions to the development of methods within DNA-based chemistry [specifically, for his fundamental contributions to the establishment of oligonucleotide-based, site-directed mutagenesis and its development for protein studies] http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1993/press.html
Link to external Web site
Richard J. Roberts & Phillip A. Sharp 1993 Physiology
or
Medicine
For discoveries of split-genes http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1993/press.html
Link to external Web site
Edmond H. Fischer & Edwin G. Krebs 1992 Physiology
or
Medicine
For discoveries concerning reversible protein phosphorylation as a biological regulatory mechanism http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1992/press.html
Link to external Web site
Elias J. Corey 1990 Chemistry For development of the theory and methodology of organic synthesis http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1990/press.html
Link to external Web site
Sidney Altman & Thomas R. Cech 1989 Chemistry For discovery of catalytic properties of RNA http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1989/press.html
Link to external Web site
Donald J. Cram 1987 Chemistry For development and use of molecules with structure-specific interactions of high selectivity http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1987/press.html
Link to external Web site
Stanley Cohen 1986 Physiology
or
Medicine
For discoveries of growth factors http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1986/press.html
Link to external Web site
Herbert A. Hauptman 1985 Chemistry For outstanding achievements in the development of direct methods for the determination of crystal structures http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1985/press.html
Link to external Web site
Michael S. Brown & Joseph L. Goldstein 1985 Physiology
or
Medicine
For discoveries concerning the regulation of cholesterol metabolism http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1985/press.html
Link to external Web site
Henry Taube 1983 Chemistry For work on the mechanisms of electron transfer reactions, especially in metal complexes http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1983/press.html
Link to external Web site
John R. Vane 1982 Physiology
or
Medicine
For discoveries concerning prostaglandins and related biologically active substances http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1982/press.html
Link to external Web site
Roald Hoffmann 1981 Chemistry For theories, developed independently, concerning the course of chemical reactions http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1981/press.html
Link to external Web site
David H. Hubel 1981 Physiology
or
Medicine
For discoveries concerning information processing in the visual system http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1981/press.html
Link to external Web site
Paul Berg 1980 Chemistry For fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1980/press.html
Link to external Web site
Walter Gilbert 1980 Chemistry For contributions concerning the determination of base sequences in nucleic acids http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1980/press.html
Link to external Web site
Herbert C. Brown 1979 Chemistry For development of the use of boron- and phosphorus-containing compounds, respectively, into important reagents in organic synthesis http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1979/press.html
Link to external Web site
Daniel Nathans & Hamilton O. Smith 1978 Physiology
or
Medicine
For the discovery of restriction enzymes and their application to problems of molecular genetics http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1978/press.html
Link to external Web site
Andrew V. Schally 1977 Physiology
or
Medicine
For discoveries concerning the peptide hormone production of the brain http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1977/press.html
Link to external Web site
William N. Lipscomb 1976 Chemistry For studies on the structure of boranes illuminating problems of chemical bonding http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1976/press.html
Link to external Web site
Christian de Duve & George E. Palade 1974 Physiology
or
Medicine
For discoveries concerning the structural and functional organization of the cell http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1974/press.html
Link to external Web site
Stanford Moore & William H. Stein 1972 Chemistry For contributions to the understanding of the connection between chemical structure and catalytic activity of the active center of the ribonuclease molecule http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1972/press.html
Link to external Web site
Earl W. Sutherland, Jr. 1971 Physiology
or
Medicine
For discoveries concerning the mechanisms of the action of hormones http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1971/press.html
Link to external Web site
Luis F. Leloir 1970 Chemistry For discovery of sugar nucleotides and their role in the biosynthesis of carbohydrates Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1970/press.html
Link to external Web site
Max Delbrück, Alfred D. Hershey & Salvador E. Luria 1969 Physiology
or
Medicine
For discoveries concerning the replication mechanism and the genetic structure of viruses http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1969/press.html
Link to external Web site
Lars Onsager 1968 Chemistry For the discovery of the reciprocal relations bearing his name, which are fundamental for the thermodynamics of irreversible processes Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1968/press.html
Link to external Web site
Robert W. Holley & H. Gobind Khorana 1968 Physiology
or
Medicine
For interpretation of the genetic code and its function in protein synthesis Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1968/press.html
Link to external Web site
Charles B. Huggins 1966 Physiology
or
Medicine
For discoveries concerning hormonal treatment of prostatic cancer Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1968/press.html
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Robert B. Woodward 1965 Chemistry For outstanding achievements in the art of organic synthesis Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
chemistry/laureates/1965/press.html
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Konrad Bloch 1964 Physiology
or
Medicine
For discoveries concerning the mechanism and regulation of thecholesterol and fatty acid metabolism Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1964/press.html
Link to external Web site
James D. Watson 1962 Physiology
or
Medicine
For discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material Nobel Prize Web site: http://www.nobelprize.org/nobel_prizes/
medicine/laureates/1962/press.html
Link to external Web site
This page last reviewed on October 21, 2014