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Items 1 - 20 of 654
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1:
Li L, Yu M, Jason RD, Shen C, Azzouz F, McLeod HL, Borges-Gonzales S, Nguyen A, Skaar T, Desta Z, Sweeney CJ, Flockhart DA.
Abstract
A mixture model approach in gene-gene and gene-environmental interactions for binary phenotypes.
J Biopharm Stat. 2008;18(6):1150-77.
PMID: 18991114 [PubMed - in process]
2:
Sangkuhl K, Berlin DS, Altman RB, Klein TE.
Abstract
PharmGKB: understanding the effects of individual genetic variants.
Drug Metab Rev. 2008;40(4):539-51.
PMID: 18949600 [PubMed - in process]
3:
Darbar D.
No Abstract
Cardiac sodium channel variants: action players with many faces.
Heart Rhythm. 2008 Oct;5(10):1441-3. Epub 2008 Aug 17. No abstract available.
PMID: 18929332 [PubMed - in process]
4:
Ferrell PB Jr, McLeod HL.
Abstract
Carbamazepine, HLA-B*1502 and risk of Stevens-Johnson syndrome and toxic epidermal necrolysis: US FDA recommendations.
Pharmacogenomics. 2008 Oct;9(10):1543-6.
PMID: 18855540 [PubMed - in process]
5:
Yu J, Miller R, Zhang W, Sharma M, Holtschlag V, Watson MA, McLeod HL.
Abstract
Copy-number analysis of topoisomerase and thymidylate synthase genes in frozen and FFPE DNAs of colorectal cancers.
Pharmacogenomics. 2008 Oct;9(10):1459-66.
PMID: 18855534 [PubMed - in process]
6:
Wang L, Weinshilboum RM.
Abstract
Pharmacogenomics: candidate gene identification, functional validation and mechanisms.
Hum Mol Genet. 2008 Oct 15;17(R2):R174-9.
PMID: 18852207 [PubMed - in process]
7:
Sharma S, Litonjua AA, Tantisira KG, Fuhlbrigge AL, Szefler SJ, Strunk RC, Zeiger RS, Murphy AJ, Weiss ST; Childhood Asthma Management Program Research Group.
Abstract
Clinical predictors and outcomes of consistent bronchodilator response in the childhood asthma management program.
J Allergy Clin Immunol. 2008 Nov;122(5):921-928.e4. Epub 2008 Oct 10.
PMID: 18848350 [PubMed - in process]
8:
Wilke RA, Berg RL, Linneman JG, Zhao C, McCarty CA, Krauss RM.
Abstract
Characterization of low-density lipoprotein cholesterol-lowering efficacy for atorvastatin in a population-based DNA biorepository.
Basic Clin Pharmacol Toxicol. 2008 Oct;103(4):354-9.
PMID: 18834356 [PubMed - in process]
9:
Murphy A, Weiss ST, Lange C.
Free in PMC
Screening and replication using the same data set: testing strategies for family-based studies in which all probands are affected.
PLoS Genet. 2008 Sep 19;4(9):e1000197.
PMID: 18802462 [PubMed - indexed for MEDLINE]
10:
Bhojwani D, Kang H, Menezes RX, Yang W, Sather H, Moskowitz NP, Min DJ, Potter JW, Harvey R, Hunger SP, Seibel N, Raetz EA, Pieters R, Horstmann MA, Relling MV, den Boer ML, Willman CL, Carroll WL; Children's Oncology Group Study; Dutch Childhood Oncology Group; German Cooperative Study Group for Childhood Acute Lymphoblastic Leukemia.
Abstract
Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected].
J Clin Oncol. 2008 Sep 20;26(27):4376-84. Erratum in: J Clin Oncol. 2008 Nov 1;26(31):5142..
PMID: 18802149 [PubMed - indexed for MEDLINE]
11:
Kurnik D, Li C, Sofowora GG, Friedman EA, Muszkat M, Xie HG, Harris PA, Williams SM, Nair UB, Wood AJ, Stein CM.
Abstract
Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade.
Pharmacogenet Genomics. 2008 Oct;18(10):895-902.
PMID: 18794726 [PubMed - indexed for MEDLINE]
12:
Yang JJ, Bhojwani D, Yang W, Cai X, Stocco G, Crews K, Wang J, Morrison D, Devidas M, Hunger SP, Willman CL, Raetz EA, Pui CH, Evans WE, Relling MV, Carroll WL.
Free in PMC
Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia.
Blood. 2008 Nov 15;112(10):4178-83. Epub 2008 Sep 2.
PMID: 18768390 [PubMed - in process]
13:
Huang RS, Duan S, Kistner EO, Hartford CM, Dolan ME.
Abstract
Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans.
Mol Cancer Ther. 2008 Sep;7(9):3038-46. Epub 2008 Sep 2.
PMID: 18765826 [PubMed - indexed for MEDLINE]
14:
Ionita-Laza I, Laird NM, Raby BA, Weiss ST, Lange C.
Abstract
On the frequency of copy number variants.
Bioinformatics. 2008 Oct 15;24(20):2350-5. Epub 2008 Aug 8.
PMID: 18689430 [PubMed - in process]
15:
Tremblay K, Lemire M, Potvin C, Tremblay A, Hunninghake GM, Raby BA, Hudson TJ, Perez-Iratxeta C, Andrade-Navarro MA, Laprise C.
Free in PMC
Genes to diseases (G2D) computational method to identify asthma candidate genes.
PLoS ONE. 2008 Aug 6;3(8):e2907.
PMID: 18682798 [PubMed - in process]
16:
Deverka PA, McLeod HL.
Abstract
Harnessing economic drivers for successful clinical implementation of pharmacogenetic testing.
Clin Pharmacol Ther. 2008 Aug;84(2):191-3.
PMID: 18679180 [PubMed - indexed for MEDLINE]
17:
Weinshilboum R.
Abstract
Pharmacogenomics of endocrine therapy in breast cancer.
Adv Exp Med Biol. 2008;630:220-31. Review.
PMID: 18637494 [PubMed - indexed for MEDLINE]
18:
Ji Y, Olson J, Zhang J, Hildebrandt M, Wang L, Ingle J, Fredericksen Z, Sellers T, Miller W, Dixon JM, Brauch H, Eichelbaum M, Justenhoven C, Hamann U, Ko Y, BrĂ¼ning T, Chang-Claude J, Wang-Gohrke S, Schaid D, Weinshilboum R.
Abstract
Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms.
Cancer Res. 2008 Jul 15;68(14):5997-6005.
PMID: 18632656 [PubMed - indexed for MEDLINE]
19:
Litonjua AA, Lasky-Su J, Schneiter K, Tantisira KG, Lazarus R, Klanderman B, Lima JJ, Irvin CG, Peters SP, Hanrahan JP, Liggett SB, Hawkins GA, Meyers DA, Bleecker ER, Lange C, Weiss ST.
Abstract
ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts.
Am J Respir Crit Care Med. 2008 Oct 1;178(7):688-94. Epub 2008 Jul 10.
PMID: 18617639 [PubMed - indexed for MEDLINE]
20:
Pacanowski MA, Gong Y, Cooper-Dehoff RM, Schork NJ, Shriver MD, Langaee TY, Pepine CJ, Johnson JA; INVEST Investigators.
Abstract
beta-adrenergic receptor gene polymorphisms and beta-blocker treatment outcomes in hypertension.
Clin Pharmacol Ther. 2008 Dec;84(6):715-21. Epub 2008 Jul 9.
PMID: 18615004 [PubMed - in process]
Items 1 - 20 of 654
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