NIGMS-supported researchers have revealed the molecular structure of aromatase, the enzyme targeted by Tamoxifen and other, related drugs.

A team of NIGMS-supported biologists has discovered that two RNA polymerases found only in plants are specialized forms of an enzyme common to all eukaryotic organisms.

NIGMS-funded researchers discovered that removing the tail of a tumor suppressor called PTEN activated the protein, which is often inactive in cancer cells.

NIGMS-supported researchers have developed a computational method that predicts how bacterial proteins fold and interact.

NIGMS-funded researchers have successfully used E. coli to synthesize natural products known as bacterial aromatic polyketides.

A study supported in part by NIGMS developed a way to detect movement within ion channels, which are major drug targets.